Jacob J - Search Results

1

Molecular studies on the toxifying effects by genetically engineered cytochromes P450.

Doehmer J, Buters JT, Luch A, Soballa V, Baird WM, Morisson H, Stegeman JJ, Townsend AJ, Greenlee WF, Glatt HR, Seidel A, Jacob J, Greim H. Doehmer J, et al. Among authors: jacob j. Drug Metab Rev. 1999 May;31(2):423-35. doi: 10.1081/dmr-100101928. Drug Metab Rev. 1999. PMID: 10335445 Review. No abstract available.

2

Cytochrome P450 mediated reactions studied in genetically engineered V79 Chinese hamster cells.

Doehmer J, Holtkamp D, Soballa V, Raab G, Schmalix W, Seidel A, Greim H, Jacob J. Doehmer J, et al. Among authors: jacob j. Pharmacogenetics. 1995;5 Spec No:S91-6. doi: 10.1097/00008571-199512001-00008. Pharmacogenetics. 1995. PMID: 7581497

3

Metabolic activation of dibenzo[a,l]pyrene by human cytochrome P450 1A1 and P450 1B1 expressed in V79 Chinese hamster cells.

Luch A, Schober W, Soballa VJ, Raab G, Greim H, Jacob J, Doehmer J, Seidel A. Luch A, et al. Among authors: jacob j. Chem Res Toxicol. 1999 Apr;12(4):353-64. doi: 10.1021/tx980240g. Chem Res Toxicol. 1999. PMID: 10207125

4

Regio- and stereoselectivity in the metabolism of benzo[c]phenanthrene mediated by genetically engineered V79 Chinese hamster cells expressing rat and human cytochromes P450.

Seidel A, Soballa VJ, Raab G, Frank H, Greim H, Grimmer G, Jacob J, Doehmer J. Seidel A, et al. Among authors: jacob j. Environ Toxicol Pharmacol. 1998 May;5(3):179-96. doi: 10.1016/s1382-6689(97)10073-4. Environ Toxicol Pharmacol. 1998. PMID: 21781864

5

Cytochrome P450-mediated activation of phenanthrene in genetically engineered V79 Chinese hamster cells.

Jacob J, Raab G, Soballa V, Schmalix WA, Grimmer G, Greim H, Doehmer J, Seidel A. Jacob J, et al. Environ Toxicol Pharmacol. 1996 Feb 15;1(1):1-11. doi: 10.1016/1382-6689(95)00003-8. Environ Toxicol Pharmacol. 1996. PMID: 21781657

6

Induction of gene expression of xenobiotic metabolism enzymes and ABC-transport proteins by PAH and a reconstituted PAH mixture in human Caco-2 cells.

Lampen A, Ebert B, Stumkat L, Jacob J, Seidel A. Lampen A, et al. Among authors: jacob j. Biochim Biophys Acta. 2004 Nov 24;1681(1):38-46. doi: 10.1016/j.bbaexp.2004.09.010. Biochim Biophys Acta. 2004. PMID: 15566942

7

Biomonitoring of polycyclic aromatic compounds in the urine of mining workers occupationally exposed to diesel exhaust.

Seidel A, Dahmann D, Krekeler H, Jacob J. Seidel A, et al. Among authors: jacob j. Int J Hyg Environ Health. 2002 Feb;204(5-6):333-8. doi: 10.1078/1438-4639-00116. Int J Hyg Environ Health. 2002. PMID: 11885357

8

Detection of carcinogenic aromatic amines in the urine of non-smokers.

Grimmer G, Dettbarn G, Seidel A, Jacob J. Grimmer G, et al. Among authors: jacob j. Sci Total Environ. 2000 Feb 28;247(1):81-90. doi: 10.1016/s0048-9697(99)00471-4. Sci Total Environ. 2000. PMID: 10721145

9

Differential protection by human glutathione S-transferase P1 against cytotoxicity of benzo[a]pyrene, dibenzo[a,l]pyrene, or their dihydrodiol metabolites, in bi-transgenic cell lines that co-express rat versus human cytochrome P4501A1.

Kabler SL, Seidel A, Jacob J, Doehmer J, Morrow CS, Townsend AJ. Kabler SL, et al. Among authors: jacob j. Chem Biol Interact. 2009 May 15;179(2-3):240-6. doi: 10.1016/j.cbi.2009.01.010. Chem Biol Interact. 2009. PMID: 19330882 Free PMC article.

10

Human intestinal Caco-2 cells display active transport of benzo[a]pyrene metabolites.

Buesen R, Mock M, Nau H, Seidel A, Jacob J, Lampen A. Buesen R, et al. Among authors: jacob j. Chem Biol Interact. 2003 Jan 6;142(3):201-21. doi: 10.1016/s0009-2797(02)00076-5. Chem Biol Interact. 2003. PMID: 12453661

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