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2002 1
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2008 4
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2012 4
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2014 3
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Page 1
HBO1 catalyzes lysine lactylation and mediates histone H3K9la to regulate gene transcription.
Niu Z, Chen C, Wang S, Lu C, Wu Z, Wang A, Mo J, Zhang J, Han Y, Yuan Y, Zhang Y, Zang Y, He C, Bai X, Tian S, Zhai G, Wu X, Zhang K. Niu Z, et al. Nat Commun. 2024 Apr 26;15(1):3561. doi: 10.1038/s41467-024-47900-6. Nat Commun. 2024. PMID: 38670996
Using site-specific antibodies, we find that HBO1 may preferentially catalyze histone H3K9la and scaffold proteins including JADE1 and BRPF2 can promote the enzymatic activity for histone Kla. ...
Using site-specific antibodies, we find that HBO1 may preferentially catalyze histone H3K9la and scaffold proteins including JADE1 an …
Genome-wide CRISPR activation screen identifies JADE3 as an antiviral activator of NF-kB-dependent IFITM3 expression.
Munir M, Embry A, Doench JG, Heaton NS, Wilen CB, Orchard RC. Munir M, et al. J Biol Chem. 2024 Apr;300(4):107153. doi: 10.1016/j.jbc.2024.107153. Epub 2024 Mar 9. J Biol Chem. 2024. PMID: 38462163 Free PMC article.
Our results suggest a distinct function for JADE3 as expression of the closely related paralogs JADE1 and JADE2 does not confer resistance to influenza A virus infection. ...
Our results suggest a distinct function for JADE3 as expression of the closely related paralogs JADE1 and JADE2 does not confer resis …
Involvement of microRNA-4680-3p against phenytoin-induced cell proliferation inhibition in human palate cells.
Tsukiboshi Y, Horita H, Mikami Y, Noguchi A, Yokota S, Ogata K, Yoshioka H. Tsukiboshi Y, et al. J Toxicol Sci. 2024;49(1):1-8. doi: 10.2131/jts.49.1. J Toxicol Sci. 2024. PMID: 38191190 Free article.
Furthermore, PHE increased miR-4680-3p expression and decreased two downstream genes (ERBB2 and JADE1). Importantly, an miR-4680-3p-specific inhibitor restored HEPM cell proliferation and altered expression of ERBB2 and JADE1 in cells treated with PHE. ...
Furthermore, PHE increased miR-4680-3p expression and decreased two downstream genes (ERBB2 and JADE1). Importantly, an miR-4680-3p-s …
JADE1 is dispensable for the brain development in mice.
Wang J, Chai B, Yang Y, Chen C, Ren Y, Li Y, Wang ZQ, Li T. Wang J, et al. Biochem Biophys Res Commun. 2024 Feb 5;695:149421. doi: 10.1016/j.bbrc.2023.149421. Epub 2023 Dec 27. Biochem Biophys Res Commun. 2024. PMID: 38171233
However, JADE1's role in mammalian brain development remains unknown. Here, we generated a new Jade1 knockout mouse line using CRISPR-Cas9 technology. ...RNA-seq analysis further showed that JADE1 loss did not affect the cerebral cortex gene expression. Our f …
However, JADE1's role in mammalian brain development remains unknown. Here, we generated a new Jade1 knockout mouse line using …
Genome-wide CRISPR activation screen identifies JADE3 as an antiviral activator of NF-kB.
Munir M, Embry A, Doench JG, Heaton NS, Wilen CB, Orchard RC. Munir M, et al. bioRxiv [Preprint]. 2023 Sep 29:2023.09.29.560128. doi: 10.1101/2023.09.29.560128. bioRxiv. 2023. PMID: 37808733 Free PMC article. Updated. Preprint.
JADE3 is both necessary and sufficient to restrict influenza A virus infection. Interestingly, expression of the closely related paralogues JADE1 and JADE2 are unable to restrict influenza A virus infection, suggesting a distinct function of JADE3. ...Specifically, we find …
JADE3 is both necessary and sufficient to restrict influenza A virus infection. Interestingly, expression of the closely related paralogues …
rs56405341 Variant Associates with Expression of C4orf33 and C4orf33 Was Downregulated in Alzheimer's Disease and Progressive Supranuclear Palsy.
Zhang Y, Xue Y, Wang L, Han Z, Wang T, Zhang H, Liu G, Xiao X. Zhang Y, et al. J Alzheimers Dis. 2023;96(1):57-64. doi: 10.3233/JAD-230327. J Alzheimers Dis. 2023. PMID: 37742642
We found that rs56405341 was significantly associated with C4orf33 mRNA expression, but not JADE1 mRNA expression in multiple brain tissues. C4orf33 was mainly expressed in cerebellar hemisphere and cerebellum, and JADE1 was mainly expressed in thyroid, and coronary …
We found that rs56405341 was significantly associated with C4orf33 mRNA expression, but not JADE1 mRNA expression in multiple brain t …
Comprehensive chromatin proteomics resolves functional phases of pluripotency and identifies changes in regulatory components.
Ugur E, de la Porte A, Qin W, Bultmann S, Ivanova A, Drukker M, Mann M, Wierer M, Leonhardt H. Ugur E, et al. Nucleic Acids Res. 2023 Apr 11;51(6):2671-2690. doi: 10.1093/nar/gkad058. Nucleic Acids Res. 2023. PMID: 36806742 Free PMC article.
These comprehensive datasets combined with extensive analyses identified phase-specific factors like QSER1 and JADE1/2/3 and provide a detailed foundation for an in-depth understanding of mechanisms that govern the phased progression of pluripotency. ...
These comprehensive datasets combined with extensive analyses identified phase-specific factors like QSER1 and JADE1/2/3 and provide …
Evaluation of differentially expressed genes during replication using gene expression landscape of monkeypox-infected MK2 cells: A bioinformatics and systems biology approach to understanding the genomic pattern of viral replication.
Chakraborty C, Bhattacharya M, Dhama K, Lee SS. Chakraborty C, et al. J Infect Public Health. 2023 Mar;16(3):399-409. doi: 10.1016/j.jiph.2023.01.015. Epub 2023 Jan 25. J Infect Public Health. 2023. PMID: 36724696 Free PMC article.
During the DEG analysis, we identified eight up-regulated genes (LOC695323, TMEM107, LOC695427, HIST1H2AD, LOC705469, PMAIP1, HIST1H2BJ, and HIST1H3D) and 16 down-regulated genes (HOXA9, BAMBI, LMO4, PAX6, AJUBA, CREBRF, CD24, JADE1, SLC7A11, EID2, SOX4, B4GALT5, PPARGC1A, …
During the DEG analysis, we identified eight up-regulated genes (LOC695323, TMEM107, LOC695427, HIST1H2AD, LOC705469, PMAIP1, HIST1H2BJ, and …
NIEHS Report on the In Vivo Repeat Dose Biological Potency Study of tert-Butylphenyl Diphenyl Phosphate (CASRN 56803-37-3) in Male Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats (Gavage Studies): NIEHS Report 03 [Internet].
Auerbach SS, Behl MV, Collins BJ, Cora MC, Fostel JM, Ingle BL, Liu YF, Luh J, Roberts GK, Shipkowski KA, Waidyanatha S, Watson ATD. Auerbach SS, et al. Research Triangle Park (NC): National Institute of Environmental Health Sciences; 2022 Oct. Research Triangle Park (NC): National Institute of Environmental Health Sciences; 2022 Oct. PMID: 36302065 Free Books & Documents. Review.
The top 10 most sensitive individual genes exhibited changes in expression at dose levels below which a reliable estimate of potency could be achieved (<21.7 mg/kg). Of these genes, eight were upregulated: Hsd17b2, Nr1d2, Jade1, Sdr42e1, Tef, Per3, Bcar3 and Akr7a3. Two …
The top 10 most sensitive individual genes exhibited changes in expression at dose levels below which a reliable estimate of potency could b …
53 results