Janson J - Search Results

1

Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide.

Janson J, Soeller WC, Roche PC, Nelson RT, Torchia AJ, Kreutter DK, Butler PC. Janson J, et al. Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7283-8. doi: 10.1073/pnas.93.14.7283. Proc Natl Acad Sci U S A. 1996. PMID: 8692984 Free PMC article.

2

Islet amyloid-associated diabetes in obese A(vy)/a mice expressing human islet amyloid polypeptide.

Soeller WC, Janson J, Hart SE, Parker JC, Carty MD, Stevenson RW, Kreutter DK, Butler PC. Soeller WC, et al. Among authors: janson j. Diabetes. 1998 May;47(5):743-50. doi: 10.2337/diabetes.47.5.743. Diabetes. 1998. PMID: 9588445

3

Increased beta-cell apoptosis prevents adaptive increase in beta-cell mass in mouse model of type 2 diabetes: evidence for role of islet amyloid formation rather than direct action of amyloid.

Butler AE, Janson J, Soeller WC, Butler PC. Butler AE, et al. Among authors: janson j. Diabetes. 2003 Sep;52(9):2304-14. doi: 10.2337/diabetes.52.9.2304. Diabetes. 2003. PMID: 12941770

4

Increased risk of type 2 diabetes in Alzheimer disease.

Janson J, Laedtke T, Parisi JE, O'Brien P, Petersen RC, Butler PC. Janson J, et al. Diabetes. 2004 Feb;53(2):474-81. doi: 10.2337/diabetes.53.2.474. Diabetes. 2004. PMID: 14747300

5

The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles.

Janson J, Ashley RH, Harrison D, McIntyre S, Butler PC. Janson J, et al. Diabetes. 1999 Mar;48(3):491-8. doi: 10.2337/diabetes.48.3.491. Diabetes. 1999. PMID: 10078548

6

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes.

Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC. Butler AE, et al. Among authors: janson j. Diabetes. 2003 Jan;52(1):102-10. doi: 10.2337/diabetes.52.1.102. Diabetes. 2003. PMID: 12502499

7

Neuronal calcium sensor-1 potentiates glucose-dependent exocytosis in pancreatic beta cells through activation of phosphatidylinositol 4-kinase beta.

Gromada J, Bark C, Smidt K, Efanov AM, Janson J, Mandic SA, Webb DL, Zhang W, Meister B, Jeromin A, Berggren PO. Gromada J, et al. Among authors: janson j. Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10303-8. doi: 10.1073/pnas.0504487102. Epub 2005 Jul 12. Proc Natl Acad Sci U S A. 2005. PMID: 16014415 Free PMC article.

8

Tomosyn is expressed in beta-cells and negatively regulates insulin exocytosis.

Zhang W, Lilja L, Mandic SA, Gromada J, Smidt K, Janson J, Takai Y, Bark C, Berggren PO, Meister B. Zhang W, et al. Among authors: janson j. Diabetes. 2006 Mar;55(3):574-81. doi: 10.2337/diabetes.55.03.06.db05-0015. Diabetes. 2006. PMID: 16505218

9

An ancient duplication of exon 5 in the Snap25 gene is required for complex neuronal development/function.

Johansson JU, Ericsson J, Janson J, Beraki S, Stanić D, Mandic SA, Wikström MA, Hökfelt T, Ogren SO, Rozell B, Berggren PO, Bark C. Johansson JU, et al. Among authors: janson j. PLoS Genet. 2008 Nov;4(11):e1000278. doi: 10.1371/journal.pgen.1000278. Epub 2008 Nov 28. PLoS Genet. 2008. PMID: 19043548 Free PMC article.

10

Discovery of AZD3839, a potent and selective BACE1 inhibitor clinical candidate for the treatment of Alzheimer disease.

Jeppsson F, Eketjäll S, Janson J, Karlström S, Gustavsson S, Olsson LL, Radesäter AC, Ploeger B, Cebers G, Kolmodin K, Swahn BM, von Berg S, Bueters T, Fälting J. Jeppsson F, et al. Among authors: janson j. J Biol Chem. 2012 Nov 30;287(49):41245-57. doi: 10.1074/jbc.M112.409110. Epub 2012 Oct 9. J Biol Chem. 2012. PMID: 23048024 Free PMC article.

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