Jarvis MF - Search Results

1

Design, synthesis, and structure-activity relationship of 6-alkynylpyrimidines as potent adenosine kinase inhibitors.

Gomtsyan A, Didomenico S, Lee CH, Matulenko MA, Kim K, Kowaluk EA, Wismer CT, Mikusa J, Yu H, Kohlhaas K, Jarvis MF, Bhagwat SS. Gomtsyan A, et al. Among authors: jarvis mf. J Med Chem. 2002 Aug 15;45(17):3639-48. doi: 10.1021/jm020049a. J Med Chem. 2002. PMID: 12166937

2

Analgesic and anti-inflammatory effects of A-286501, a novel orally active adenosine kinase inhibitor.

Jarvis MF, Yu H, McGaraughty S, Wismer CT, Mikusa J, Zhu C, Chu K, Kohlhaas K, Cowart M, Lee CH, Stewart AO, Cox BF, Polakowski J, Kowaluk EA. Jarvis MF, et al. Pain. 2002 Mar;96(1-2):107-18. doi: 10.1016/s0304-3959(01)00435-3. Pain. 2002. PMID: 11932067

3

Comparison of the ability of adenosine kinase inhibitors and adenosine receptor agonists to attenuate thermal hyperalgesia and reduce motor performance in rats.

Jarvis MF, Mikusa J, Chu KL, Wismer CT, Honore P, Kowaluk EA, McGaraughty S. Jarvis MF, et al. Pharmacol Biochem Behav. 2002 Oct;73(3):573-81. doi: 10.1016/s0091-3057(02)00840-7. Pharmacol Biochem Behav. 2002. PMID: 12151032

4

Synthesis and structure-activity relationships of 5-heteroatom-substituted pyridopyrimidines as adenosine kinase inhibitors.

Gfesser GA, Bayburt EK, Cowart M, DiDomenico S, Gomtsyan A, Lee CH, Stewart AO, Jarvis MF, Kowaluk EA, Bhagwat SS. Gfesser GA, et al. Among authors: jarvis mf. Eur J Med Chem. 2003 Mar;38(3):245-52. doi: 10.1016/s0223-5234(03)00019-9. Eur J Med Chem. 2003. PMID: 12667691

5

Adenosine kinase inhibitors: polar 7-substitutent of pyridopyrimidine derivatives improving their locomotor selectivity.

Zheng GZ, Mao Y, Lee CH, Pratt JK, Koenig JR, Perner RJ, Cowart MD, Gfesser GA, McGaraughty S, Chu KL, Zhu C, Yu H, Kohlhaas K, Alexander KM, Wismer CT, Mikusa J, Jarvis MF, Kowaluk EA, Stewart AO. Zheng GZ, et al. Among authors: jarvis mf. Bioorg Med Chem Lett. 2003 Sep 15;13(18):3041-4. doi: 10.1016/s0960-894x(03)00642-5. Bioorg Med Chem Lett. 2003. PMID: 12941329

6

5,6,7-trisubstituted 4-aminopyrido[2,3-d]pyrimidines as novel inhibitors of adenosine kinase.

Perner RJ, Gu YG, Lee CH, Bayburt EK, McKie J, Alexander KM, Kohlhaas KL, Wismer CT, Mikusa J, Jarvis MF, Kowaluk EA, Bhagwat SS. Perner RJ, et al. Among authors: jarvis mf. J Med Chem. 2003 Nov 20;46(24):5249-57. doi: 10.1021/jm030327l. J Med Chem. 2003. PMID: 14613327

7

Synthesis and biological evaluation of pteridine and pyrazolopyrimidine based adenosine kinase inhibitors.

Gomtsyan A, Didomenico S, Lee CH, Stewart AO, Bhagwat SS, Kowaluk EA, Jarvis MF. Gomtsyan A, et al. Among authors: jarvis mf. Bioorg Med Chem Lett. 2004 Aug 16;14(16):4165-8. doi: 10.1016/j.bmcl.2004.06.029. Bioorg Med Chem Lett. 2004. PMID: 15261263

8

Novel transient receptor potential vanilloid 1 receptor antagonists for the treatment of pain: structure-activity relationships for ureas with quinoline, isoquinoline, quinazoline, phthalazine, quinoxaline, and cinnoline moieties.

Gomtsyan A, Bayburt EK, Schmidt RG, Zheng GZ, Perner RJ, Didomenico S, Koenig JR, Turner S, Jinkerson T, Drizin I, Hannick SM, Macri BS, McDonald HA, Honore P, Wismer CT, Marsh KC, Wetter J, Stewart KD, Oie T, Jarvis MF, Surowy CS, Faltynek CR, Lee CH. Gomtsyan A, et al. Among authors: jarvis mf. J Med Chem. 2005 Feb 10;48(3):744-52. doi: 10.1021/jm0492958. J Med Chem. 2005. PMID: 15689158

9

5-(3-Bromophenyl)-7-(6-morpholin-4-ylpyridin-3-yl)pyrido[2,3-d]pyrimidin-4-ylamine: structure-activity relationships of 7-substituted heteroaryl analogs as non-nucleoside adenosine kinase inhibitors.

Matulenko MA, Lee CH, Jiang M, Frey RR, Cowart MD, Bayburt EK, Didomenico S, Gfesser GA, Gomtsyan A, Zheng GZ, McKie JA, Stewart AO, Yu H, Kohlhaas KL, Alexander KM, McGaraughty S, Wismer CT, Mikusa J, Marsh KC, Snyder RD, Diehl MS, Kowaluk EA, Jarvis MF, Bhagwat SS. Matulenko MA, et al. Among authors: jarvis mf. Bioorg Med Chem. 2005 Jun 1;13(11):3705-20. doi: 10.1016/j.bmc.2005.03.023. Bioorg Med Chem. 2005. PMID: 15863000

10

Synthesis and biological evaluation of 6,7-disubstituted 4-aminopyrido[2,3-d]pyrimidines as adenosine kinase inhibitors.

Perner RJ, Lee CH, Jiang M, Gu YG, Didomenico S, Bayburt EK, Alexander KM, Kohlhaas KL, Jarvis MF, Kowaluk EL, Bhagwat SS. Perner RJ, et al. Among authors: jarvis mf. Bioorg Med Chem Lett. 2005 Jun 2;15(11):2803-7. doi: 10.1016/j.bmcl.2005.03.098. Epub 2005 Apr 25. Bioorg Med Chem Lett. 2005. PMID: 15911258

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