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Delta-4-androstene-3,17-dione binds androgen receptor, promotes myogenesis in vitro, and increases serum testosterone levels, fat-free mass, and muscle strength in hypogonadal men.
Jasuja R, Ramaraj P, Mac RP, Singh AB, Storer TW, Artaza J, Miller A, Singh R, Taylor WE, Lee ML, Davidson T, Sinha-Hikim I, Gonzalez-Cadavid N, Bhasin S. Jasuja R, et al. J Clin Endocrinol Metab. 2005 Feb;90(2):855-63. doi: 10.1210/jc.2004-1577. Epub 2004 Nov 2. J Clin Endocrinol Metab. 2005. PMID: 15522925
Tetrahydrogestrinone is an androgenic steroid that stimulates androgen receptor-mediated, myogenic differentiation in C3H10T1/2 multipotent mesenchymal cells and promotes muscle accretion in orchidectomized male rats.
Jasuja R, Catlin DH, Miller A, Chang YC, Herbst KL, Starcevic B, Artaza JN, Singh R, Datta G, Sarkissian A, Chandsawangbhuwana C, Baker M, Bhasin S. Jasuja R, et al. Endocrinology. 2005 Oct;146(10):4472-8. doi: 10.1210/en.2005-0448. Epub 2005 Jun 23. Endocrinology. 2005. PMID: 15976054
Effects of dihydrotestosterone on differentiation and proliferation of human mesenchymal stem cells and preadipocytes.
Gupta V, Bhasin S, Guo W, Singh R, Miki R, Chauhan P, Choong K, Tchkonia T, Lebrasseur NK, Flanagan JN, Hamilton JA, Viereck JC, Narula NS, Kirkland JL, Jasuja R. Gupta V, et al. Among authors: jasuja r. Mol Cell Endocrinol. 2008 Dec 16;296(1-2):32-40. doi: 10.1016/j.mce.2008.08.019. Epub 2008 Aug 28. Mol Cell Endocrinol. 2008. PMID: 18801408 Free PMC article.
Regulation of myogenic differentiation by androgens: cross talk between androgen receptor/ beta-catenin and follistatin/transforming growth factor-beta signaling pathways.
Singh R, Bhasin S, Braga M, Artaza JN, Pervin S, Taylor WE, Krishnan V, Sinha SK, Rajavashisth TB, Jasuja R. Singh R, et al. Among authors: jasuja r. Endocrinology. 2009 Mar;150(3):1259-68. doi: 10.1210/en.2008-0858. Epub 2008 Oct 23. Endocrinology. 2009. PMID: 18948405 Free PMC article.
105 results