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Synergistic tumor suppression by coexpression of FUS1 and p53 is associated with down-regulation of murine double minute-2 and activation of the apoptotic protease-activating factor 1-dependent apoptotic pathway in human non-small cell lung cancer cells.
Deng WG, Kawashima H, Wu G, Jayachandran G, Xu K, Minna JD, Roth JA, Ji L. Deng WG, et al. Among authors: jayachandran g. Cancer Res. 2007 Jan 15;67(2):709-17. doi: 10.1158/0008-5472.CAN-06-3463. Cancer Res. 2007. PMID: 17234782
Phase I clinical trial of systemically administered TUSC2(FUS1)-nanoparticles mediating functional gene transfer in humans.
Lu C, Stewart DJ, Lee JJ, Ji L, Ramesh R, Jayachandran G, Nunez MI, Wistuba II, Erasmus JJ, Hicks ME, Grimm EA, Reuben JM, Baladandayuthapani V, Templeton NS, McMannis JD, Roth JA. Lu C, et al. Among authors: jayachandran g. PLoS One. 2012;7(4):e34833. doi: 10.1371/journal.pone.0034833. Epub 2012 Apr 25. PLoS One. 2012. PMID: 22558101 Free PMC article. Clinical Trial.
Exogenous Restoration of TUSC2 Expression Induces Responsiveness to Erlotinib in Wildtype Epidermal Growth Factor Receptor (EGFR) Lung Cancer Cells through Context Specific Pathways Resulting in Enhanced Therapeutic Efficacy.
Dai B, Yan S, Lara-Guerra H, Kawashima H, Sakai R, Jayachandran G, Majidi M, Mehran R, Wang J, Bekele BN, Baladandayuthapani V, Yoo SY, Wang Y, Ying J, Meng F, Ji L, Roth JA. Dai B, et al. Among authors: jayachandran g. PLoS One. 2015 Jun 8;10(6):e0123967. doi: 10.1371/journal.pone.0123967. eCollection 2015. PLoS One. 2015. PMID: 26053020 Free PMC article.
33 results