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A novel, multitargeted endogenous metabolic modulator composition impacts metabolism, inflammation, and fibrosis in nonalcoholic steatohepatitis-relevant primary human cell models.
Daou N, Viader A, Cokol M, Nitzel A, Chakravarthy MV, Afeyan R, Tramontin T, Marukian S, Hamill MJ. Daou N, et al. Sci Rep. 2021 Jun 4;11(1):11861. doi: 10.1038/s41598-021-88913-1. Sci Rep. 2021. PMID: 34088912 Free PMC article.
Nonalcoholic steatohepatitis (NASH) is a complex metabolic disease of heterogeneous and multifactorial pathogenesis that may benefit from coordinated multitargeted interventions. ...EMMs often serve as master regulators and signaling agents for metabolic pathways th …
Nonalcoholic steatohepatitis (NASH) is a complex metabolic disease of heterogeneous and multifactorial pathogenesis that may b …
Newer second-line glucose-lowering drugs versus thiazolidinediones on cirrhosis risk among older US adult patients with type 2 diabetes.
Yang JY, Moon AM, Kim H, Pate V, Barritt AS 4th, Crowley MJ, Buse JB, Stürmer T, Alexopoulos AS. Yang JY, et al. J Diabetes Complications. 2020 Nov;34(11):107706. doi: 10.1016/j.jdiacomp.2020.107706. Epub 2020 Aug 5. J Diabetes Complications. 2020. PMID: 32843283 Free PMC article.
AIMS: Type 2 diabetes (T2D) accelerates progression of chronic liver disease to cirrhosis, yet the effects of most glucose-lowering drugs (GLDs) on cirrhosis risk in T2D are unknown. To address this gap, we compared cirrhosis risk following initiation of newer secon …
AIMS: Type 2 diabetes (T2D) accelerates progression of chronic liver disease to cirrhosis, yet the effects of most glucose-low …
Is the correlation between hydro-environmental variables consistent with their own time variability degrees in a large-scale loessial watershed?
Wu L, Yen H, Arnold JG, Ma X. Wu L, et al. Sci Total Environ. 2020 Jun 20;722:137737. doi: 10.1016/j.scitotenv.2020.137737. Epub 2020 Mar 14. Sci Total Environ. 2020. PMID: 32208241
(i) The coupled modeling framework based on SWAT (Soil and Water Assessment Tool), statistics and fractal theory is a time series analysis method that is particularly suitable for the evaluation of long-range correlation of non-linear time series. The Nash-Sutcliffe Effici …
(i) The coupled modeling framework based on SWAT (Soil and Water Assessment Tool), statistics and fractal theory is a time series analysis m …
Outcomes in Patients with Vasodilatory Shock and Renal Replacement Therapy Treated with Intravenous Angiotensin II.
Tumlin JA, Murugan R, Deane AM, Ostermann M, Busse LW, Ham KR, Kashani K, Szerlip HM, Prowle JR, Bihorac A, Finkel KW, Zarbock A, Forni LG, Lynch SJ, Jensen J, Kroll S, Chawla LS, Tidmarsh GF, Bellomo R; Angiotensin II for the Treatment of High-Output Shock 3 (ATHOS-3) Investigators. Tumlin JA, et al. Crit Care Med. 2018 Jun;46(6):949-957. doi: 10.1097/CCM.0000000000003092. Crit Care Med. 2018. PMID: 29509568 Free PMC article.