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Effect of genetic background on phenotype variability in transgenic mouse models of amyotrophic lateral sclerosis: a window of opportunity in the search for genetic modifiers.
Amyotroph Lateral Scler. 2011 Mar;12(2):79-86. doi: 10.3109/17482968.2010.550626. Epub 2011 Jan 17.
Amyotroph Lateral Scler. 2011.
PMID: 21241159
Review.
Effect of transgene copy number on survival in the G93A SOD1 transgenic mouse model of ALS.
Alexander GM, Erwin KL, Byers N, Deitch JS, Augelli BJ, Blankenhorn EP, Heiman-Patterson TD.
Alexander GM, et al. Among authors: deitch js.
Brain Res Mol Brain Res. 2004 Nov 4;130(1-2):7-15. doi: 10.1016/j.molbrainres.2004.07.002.
Brain Res Mol Brain Res. 2004.
PMID: 15519671
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Phenotype of transgenic mice carrying a very low copy number of the mutant human G93A superoxide dismutase-1 gene associated with amyotrophic lateral sclerosis.
Deitch JS, Alexander GM, Bensinger A, Yang S, Jiang JT, Heiman-Patterson TD.
Deitch JS, et al.
PLoS One. 2014 Jun 19;9(6):e99879. doi: 10.1371/journal.pone.0099879. eCollection 2014.
PLoS One. 2014.
PMID: 24945277
Free PMC article.
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Reductions in motor unit number estimates (MUNE) precede motor neuron loss in the plasma membrane calcium ATPase 2 (PMCA2)-heterozygous mice.
Souayah N, Sharovetskaya A, Kurnellas MP, Myerson M, Deitch JS, Elkabes S.
Souayah N, et al. Among authors: deitch js.
Exp Neurol. 2008 Dec;214(2):341-346. doi: 10.1016/j.expneurol.2008.09.002. Epub 2008 Sep 19.
Exp Neurol. 2008.
PMID: 18848933
Free PMC article.
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GLT-1 glutamate transporter levels are unchanged in mice expressing G93A human mutant SOD1.
Deitch JS, Alexander GM, Del Valle L, Heiman-Patterson TD.
Deitch JS, et al.
J Neurol Sci. 2002 Jan 15;193(2):117-26. doi: 10.1016/s0022-510x(01)00656-6.
J Neurol Sci. 2002.
PMID: 11790392
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A major QTL on mouse chromosome 17 resulting in lifespan variability in SOD1-G93A transgenic mouse models of amyotrophic lateral sclerosis.
Sher RB, Heiman-Patterson TD, Blankenhorn EA, Jiang J, Alexander G, Deitch JS, Cox GA.
Sher RB, et al. Among authors: deitch js.
Amyotroph Lateral Scler Frontotemporal Degener. 2014 Dec;15(7-8):588-600. doi: 10.3109/21678421.2014.932381. Epub 2014 Jul 10.
Amyotroph Lateral Scler Frontotemporal Degener. 2014.
PMID: 25008789
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