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2004 | 1 |
2005 | 3 |
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Page 1
Identification and characterization of amino-piperidinequinolones and quinazolinones as MCHr1 antagonists.
Bioorg Med Chem Lett. 2006 May 15;16(10):2621-7. doi: 10.1016/j.bmcl.2006.02.044. Epub 2006 Mar 9.
Bioorg Med Chem Lett. 2006.
PMID: 16524729
Discovery and characterization of aminopiperidinecoumarin melanin concentrating hormone receptor 1 antagonists.
Kym PR, Iyengar R, Souers AJ, Lynch JK, Judd AS, Gao J, Freeman J, Mulhern M, Zhao G, Vasudevan A, Wodka D, Blackburn C, Brown J, Che JL, Cullis C, Lai SJ, LaMarche MJ, Marsilje T, Roses J, Sells T, Geddes B, Govek E, Patane M, Fry D, Dayton BD, Brodjian S, Falls D, Brune M, Bush E, Shapiro R, Knourek-Segel V, Fey T, McDowell C, Reinhart GA, Preusser LC, Marsh K, Hernandez L, Sham HL, Collins CA.
Kym PR, et al. Among authors: che jl.
J Med Chem. 2005 Sep 22;48(19):5888-91. doi: 10.1021/jm050598r.
J Med Chem. 2005.
PMID: 16161992
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Identification of 2-[2-[2-(5-bromo-2- methoxyphenyl)-ethyl]-3-fluorophenyl]-4,5-dihydro-1H-imidazole (ML00253764), a small molecule melanocortin 4 receptor antagonist that effectively reduces tumor-induced weight loss in a mouse model.
Vos TJ, Caracoti A, Che JL, Dai M, Farrer CA, Forsyth NE, Drabic SV, Horlick RA, Lamppu D, Yowe DL, Balani S, Li P, Zeng H, Joseph IB, Rodriguez LE, Maguire MP, Patane MA, Claiborne CF.
Vos TJ, et al. Among authors: che jl.
J Med Chem. 2004 Mar 25;47(7):1602-4. doi: 10.1021/jm034244g.
J Med Chem. 2004.
PMID: 15027849
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Identification of ortho-amino benzamides and nicotinamides as MCHr1 antagonists.
Vasudevan A, LaMarche MJ, Blackburn C, Che JL, Luchaco-Cullis CA, Lai S, Marsilje TH, Patane MA, Souers AJ, Wodka D, Geddes B, Chen S, Brodjian S, Falls DH, Dayton BD, Bush E, Brune M, Shapiro RD, Marsh KC, Hernandez LE, Sham HL, Collins CA, Kym PR.
Vasudevan A, et al. Among authors: che jl.
Bioorg Med Chem Lett. 2005 Oct 1;15(19):4174-9. doi: 10.1016/j.bmcl.2005.06.089.
Bioorg Med Chem Lett. 2005.
PMID: 16085414
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Identification of aminopiperidine benzamides as MCHr1 antagonists.
Vasudevan A, Verzal MK, Wodka D, Souers AJ, Blackburn C, Che JL, Lai S, Brodjian S, Falls DH, Dayton BD, Govek E, Daniels T, Geddes B, Marsh KC, Hernandez LE, Collins CA, Kym PR.
Vasudevan A, et al. Among authors: che jl.
Bioorg Med Chem Lett. 2005 Jul 15;15(14):3412-6. doi: 10.1016/j.bmcl.2005.05.023.
Bioorg Med Chem Lett. 2005.
PMID: 15950463
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