Jiang H - Search Results

1

Synphilin-1 attenuates mutant LRRK2-induced neurodegeneration in Parkinson's disease models.

Liu J, Li T, Thomas JM, Pei Z, Jiang H, Engelender S, Ross CA, Smith WW. Liu J, et al. Among authors: jiang h. Hum Mol Genet. 2016 Feb 15;25(4):672-80. doi: 10.1093/hmg/ddv504. Epub 2016 Jan 6. Hum Mol Genet. 2016. PMID: 26744328 Free PMC article.

2

A structure-based analysis of huntingtin mutant polyglutamine aggregation and toxicity: evidence for a compact beta-sheet structure.

Poirier MA, Jiang H, Ross CA. Poirier MA, et al. Among authors: jiang h. Hum Mol Genet. 2005 Mar 15;14(6):765-74. doi: 10.1093/hmg/ddi071. Epub 2005 Feb 2. Hum Mol Genet. 2005. PMID: 15689354

3

Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity.

Smith WW, Jiang H, Pei Z, Tanaka Y, Morita H, Sawa A, Dawson VL, Dawson TM, Ross CA. Smith WW, et al. Among authors: jiang h. Hum Mol Genet. 2005 Dec 15;14(24):3801-11. doi: 10.1093/hmg/ddi396. Epub 2005 Oct 20. Hum Mol Genet. 2005. PMID: 16239241

4

Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration.

Smith WW, Pei Z, Jiang H, Moore DJ, Liang Y, West AB, Dawson VL, Dawson TM, Ross CA. Smith WW, et al. Among authors: jiang h. Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18676-81. doi: 10.1073/pnas.0508052102. Epub 2005 Dec 13. Proc Natl Acad Sci U S A. 2005. PMID: 16352719 Free PMC article.

5

Parkinson's disease genetic mutations increase cell susceptibility to stress: mutant alpha-synuclein enhances H2O2- and Sin-1-induced cell death.

Jiang H, Wu YC, Nakamura M, Liang Y, Tanaka Y, Holmes S, Dawson VL, Dawson TM, Ross CA, Smith WW. Jiang H, et al. Neurobiol Aging. 2007 Nov;28(11):1709-17. doi: 10.1016/j.neurobiolaging.2006.07.017. Epub 2006 Sep 15. Neurobiol Aging. 2007. PMID: 16978743

6

Kinase activity of mutant LRRK2 mediates neuronal toxicity.

Smith WW, Pei Z, Jiang H, Dawson VL, Dawson TM, Ross CA. Smith WW, et al. Among authors: jiang h. Nat Neurosci. 2006 Oct;9(10):1231-3. doi: 10.1038/nn1776. Epub 2006 Sep 17. Nat Neurosci. 2006. PMID: 16980962

7

A Drosophila model for LRRK2-linked parkinsonism.

Liu Z, Wang X, Yu Y, Li X, Wang T, Jiang H, Ren Q, Jiao Y, Sawa A, Moran T, Ross CA, Montell C, Smith WW. Liu Z, et al. Among authors: jiang h. Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2693-8. doi: 10.1073/pnas.0708452105. Epub 2008 Feb 7. Proc Natl Acad Sci U S A. 2008. PMID: 18258746 Free PMC article.

8

Cell death triggered by polyglutamine-expanded huntingtin in a neuronal cell line is associated with degradation of CREB-binding protein.

Jiang H, Nucifora FC Jr, Ross CA, DeFranco DB. Jiang H, et al. Hum Mol Genet. 2003 Jan 1;12(1):1-12. doi: 10.1093/hmg/ddg002. Hum Mol Genet. 2003. PMID: 12490527

9

Depletion of CBP is directly linked with cellular toxicity caused by mutant huntingtin.

Jiang H, Poirier MA, Liang Y, Pei Z, Weiskittel CE, Smith WW, DeFranco DB, Ross CA. Jiang H, et al. Neurobiol Dis. 2006 Sep;23(3):543-51. doi: 10.1016/j.nbd.2006.04.011. Neurobiol Dis. 2006. PMID: 16766198

10

CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity.

Ko HS, Bailey R, Smith WW, Liu Z, Shin JH, Lee YI, Zhang YJ, Jiang H, Ross CA, Moore DJ, Patterson C, Petrucelli L, Dawson TM, Dawson VL. Ko HS, et al. Among authors: jiang h. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2897-902. doi: 10.1073/pnas.0810123106. Epub 2009 Feb 5. Proc Natl Acad Sci U S A. 2009. PMID: 19196961 Free PMC article.

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