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Transient conformers of LacY are trapped by nanobodies.
Smirnova I, Kasho V, Jiang X, Pardon E, Steyaert J, Kaback HR. Smirnova I, et al. Among authors: jiang x. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13839-44. doi: 10.1073/pnas.1519485112. Epub 2015 Oct 28. Proc Natl Acad Sci U S A. 2015. PMID: 26512108 Free PMC article.
Evidence for an intermediate conformational state of LacY.
Jiang X, Guan L, Zhou Y, Hong WX, Zhang Q, Kaback HR. Jiang X, et al. Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):E698-704. doi: 10.1073/pnas.1201107109. Epub 2012 Feb 21. Proc Natl Acad Sci U S A. 2012. PMID: 22355148 Free PMC article.
Galactoside-binding site in LacY.
Jiang X, Villafuerte MK, Andersson M, White SH, Kaback HR. Jiang X, et al. Biochemistry. 2014 Mar 11;53(9):1536-43. doi: 10.1021/bi401716z. Epub 2014 Feb 26. Biochemistry. 2014. PMID: 24520888 Free PMC article.
Outward-facing conformers of LacY stabilized by nanobodies.
Smirnova I, Kasho V, Jiang X, Pardon E, Steyaert J, Kaback HR. Smirnova I, et al. Among authors: jiang x. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18548-53. doi: 10.1073/pnas.1422265112. Epub 2014 Dec 15. Proc Natl Acad Sci U S A. 2014. PMID: 25512549 Free PMC article.
Thermodynamics of Nanobody Binding to Lactose Permease.
Hariharan P, Andersson M, Jiang X, Pardon E, Steyaert J, Kaback HR, Guan L. Hariharan P, et al. Among authors: jiang x. Biochemistry. 2016 Oct 25;55(42):5917-5926. doi: 10.1021/acs.biochem.6b00826. Epub 2016 Oct 12. Biochemistry. 2016. PMID: 27686537 Free PMC article.
An Asymmetric Conformational Change in LacY.
Smirnova I, Kasho V, Jiang X, Kaback HR. Smirnova I, et al. Among authors: jiang x. Biochemistry. 2017 Apr 4;56(13):1943-1950. doi: 10.1021/acs.biochem.7b00134. Epub 2017 Mar 23. Biochemistry. 2017. PMID: 28300394 Free PMC article.
Oversized galactosides as a probe for conformational dynamics in LacY.
Smirnova I, Kasho V, Jiang X, Chen HM, Withers SG, Kaback HR. Smirnova I, et al. Among authors: jiang x. Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):4146-4151. doi: 10.1073/pnas.1800706115. Epub 2018 Mar 30. Proc Natl Acad Sci U S A. 2018. PMID: 29602806 Free PMC article.
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