Jimeno ML - Search Results

1

Potential multifunctional inhibitors of HIV-1 reverse transcriptase. Novel [AZT]-[TSAO-T] and [d4T]-[TSAO-T] heterodimers modified in the linker and in the dideoxynucleoside region.

Velázquez S, Tuñón V, Jimeno ML, Chamorro C, De Clercq E, Balzarini J, Camarasa MJ. Velázquez S, et al. Among authors: jimeno ml. J Med Chem. 1999 Dec 16;42(25):5188-96. doi: 10.1021/jm991092+. J Med Chem. 1999. PMID: 10602704

2

Synthesis of novel Bi-, Tri-, and tetracyclic nucleosides by reaction of a common cyclic enamine derived from TSAO-T with nucleophiles.

Bonache MC, Chamorro C, Cordeiro A, Camarasa MJ, Jimeno ML, San-Félix A. Bonache MC, et al. Among authors: jimeno ml. J Org Chem. 2004 Dec 10;69(25):8758-66. doi: 10.1021/jo048706p. J Org Chem. 2004. PMID: 15575754

3

9-Arylpurines as a novel class of enterovirus inhibitors.

Aguado L, Thibaut HJ, Priego EM, Jimeno ML, Camarasa MJ, Neyts J, Pérez-Pérez MJ. Aguado L, et al. Among authors: jimeno ml. J Med Chem. 2010 Jan 14;53(1):316-24. doi: 10.1021/jm901240p. J Med Chem. 2010. PMID: 19924996

4

Synthesis and anti-HIV activity of [AZT]-[TSAO-T] and [AZT]-[HEPT] dimers as potential multifunctional inhibitors of HIV-1 reverse transcriptase.

Velázquez S, Alvarez R, San-Félix A, Jimeno ML, De Clercq E, Balzarini J, Camarasa MJ. Velázquez S, et al. Among authors: jimeno ml. J Med Chem. 1995 May 12;38(10):1641-9. doi: 10.1021/jm00010a008. J Med Chem. 1995. PMID: 7538589

5

Abasic analogues of TSAO-T as the first sugar derivatives that specifically inhibit HIV-1 reverse transcriptase.

Velázquez S, Chamorro C, Pérez-Pérez MJ, Alvarez R, Jimeno ML, Martín-Domenech A, Pérez C, Gago F, De Clercq E, Balzarini J, San-Félix A, Camarasa MJ. Velázquez S, et al. Among authors: jimeno ml. J Med Chem. 1998 Nov 5;41(23):4636-47. doi: 10.1021/jm980370m. J Med Chem. 1998. PMID: 9804703 Free article.

6

Novel 3'-spiro nucleoside analogues of TSAO-T. Part II. A comparative study based on NMR conformational analysis in solution and theoretical calculations.

Alvarez R, Jimeno ML, Gago F, Balzarini J, Pérez-Pérez MJ, Camarasa MJ. Alvarez R, et al. Among authors: jimeno ml. Antivir Chem Chemother. 1998 Jul;9(4):333-40. Antivir Chem Chemother. 1998. PMID: 9875412

7

Novel series of [ddN]-[TSAO-T] heterodimers as potential bi-functional inhibitors of HIV-1 RT. Studies in the linker and ddN region.

Velázquez S, Tuñón V, Jimeno ML, Pérez-Pérez MJ, San-Félix A, Chamorro C, Lobatón E, Esteban-Gamboa A, De Clercq E, Balzarini J, Camarasa MJ. Velázquez S, et al. Among authors: jimeno ml. Nucleosides Nucleotides. 1999 Apr-May;18(4-5):1029-30. doi: 10.1080/15257779908041640. Nucleosides Nucleotides. 1999. PMID: 10432737

8

"Second generation" of TSAO compounds directed against HIV-1 TSAO-resistant strains.

Lobatón E, Velázquez S, Pérez-Pérez MJ, Jimeno ML, San-Félix A, De Clercq E, Balzarini J, Camarasa MJ. Lobatón E, et al. Among authors: jimeno ml. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):707-10. doi: 10.1081/NCN-100002356. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11563097

9

Synthesis and structural characterization of pyrimidine bi- and tricyclic nucleosides with sugar puckers conformationally locked into the eastern region of the pseudorotational cycle.

Chamorro C, Luengo SM, Bonache MC, Velázquez S, Pérez-Pérez MJ, Camarasa MJ, Gago F, Jimeno ML, San-Félix A. Chamorro C, et al. Among authors: jimeno ml. J Org Chem. 2003 Aug 22;68(17):6695-704. doi: 10.1021/jo034088l. J Org Chem. 2003. PMID: 12919035

10

Unprecedented lability of the 5'-O-tert-butyldimethylsilyl group from 3'-spiro-5''-(4''-acylamino-1'',2''-oxathiole-2'',2''-dioxide) nucleoside derivatives via neighboring group participation of the 4''-acylamino residue.

de Castro S, Lozano A, Jimeno ML, Pérez-Pérez MJ, San-Félix A, Camarasa MJ, Velázquez S. de Castro S, et al. Among authors: jimeno ml. J Org Chem. 2006 Feb 17;71(4):1407-15. doi: 10.1021/jo0520588. J Org Chem. 2006. PMID: 16468788

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