John SWM - Search Results

1

Genetic background modifies vulnerability to glaucoma-related phenotypes in Lmx1b mutant mice.

Tolman NG, Balasubramanian R, Macalinao DG, Kearney AL, MacNicoll KH, Montgomery CL, de Vries WN, Jackson IJ, Cross SH, Kizhatil K, Nair KS, John SWM. Tolman NG, et al. Among authors: john swm. Dis Model Mech. 2021 Feb 19;14(2):dmm046953. doi: 10.1242/dmm.046953. Dis Model Mech. 2021. PMID: 33462143 Free PMC article.

2

A dominant-negative mutation of mouse Lmx1b causes glaucoma and is semi-lethal via LDB1-mediated dimerization [corrected].

Cross SH, Macalinao DG, McKie L, Rose L, Kearney AL, Rainger J, Thaung C, Keighren M, Jadeja S, West K, Kneeland SC, Smith RS, Howell GR, Young F, Robertson M, van T' Hof R, John SW, Jackson IJ. Cross SH, et al. PLoS Genet. 2014 May 8;10(5):e1004359. doi: 10.1371/journal.pgen.1004359. eCollection 2014 May. PLoS Genet. 2014. PMID: 24809698 Free PMC article.

3

YBR/EiJ mice: a new model of glaucoma caused by genes on chromosomes 4 and 17.

Nair KS, Cosma M, Raghupathy N, Sellarole MA, Tolman NG, de Vries W, Smith RS, John SW. Nair KS, et al. Dis Model Mech. 2016 Aug 1;9(8):863-71. doi: 10.1242/dmm.024307. Epub 2016 Jun 9. Dis Model Mech. 2016. PMID: 27483353 Free PMC article.

4

Loss of PRSS56 function leads to ocular angle defects and increased susceptibility to high intraocular pressure.

Labelle-Dumais C, Pyatla G, Paylakhi S, Tolman NG, Hameed S, Seymens Y, Dang E, Mandal AK, Senthil S, Khanna RC, Kabra M, Kaur I, John SWM, Chakrabarti S, Nair KS. Labelle-Dumais C, et al. Among authors: john swm. Dis Model Mech. 2020 May 29;13(5):dmm042853. doi: 10.1242/dmm.042853. Dis Model Mech. 2020. PMID: 32152063 Free PMC article.

5

Alteration of the serine protease PRSS56 causes angle-closure glaucoma in mice and posterior microphthalmia in humans and mice.

Nair KS, Hmani-Aifa M, Ali Z, Kearney AL, Ben Salem S, Macalinao DG, Cosma IM, Bouassida W, Hakim B, Benzina Z, Soto I, Söderkvist P, Howell GR, Smith RS, Ayadi H, John SW. Nair KS, et al. Nat Genet. 2011 Jun;43(6):579-84. doi: 10.1038/ng.813. Epub 2011 May 1. Nat Genet. 2011. PMID: 21532570 Free PMC article.

6

Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma.

Howell GR, Soto I, Zhu X, Ryan M, Macalinao DG, Sousa GL, Caddle LB, MacNicoll KH, Barbay JM, Porciatti V, Anderson MG, Smith RS, Clark AF, Libby RT, John SW. Howell GR, et al. J Clin Invest. 2012 Apr;122(4):1246-61. doi: 10.1172/JCI61135. Epub 2012 Mar 19. J Clin Invest. 2012. PMID: 22426214 Free PMC article.

7

Generating embryonic stem cells from the inbred mouse strain DBA/2J, a model of glaucoma and other complex diseases.

Reinholdt LG, Howell GR, Czechanski AM, Macalinao DG, Macnicoll KH, Lin CS, Donahue LR, John SW. Reinholdt LG, et al. PLoS One. 2012;7(11):e50081. doi: 10.1371/journal.pone.0050081. Epub 2012 Nov 27. PLoS One. 2012. PMID: 23209647 Free PMC article.

8

Determining immune components necessary for progression of pigment dispersing disease to glaucoma in DBA/2J mice.

Nair KS, Barbay J, Smith RS, Masli S, John SW. Nair KS, et al. BMC Genet. 2014 Mar 28;15:42. doi: 10.1186/1471-2156-15-42. BMC Genet. 2014. PMID: 24678736 Free PMC article.

9

Combinatorial targeting of early pathways profoundly inhibits neurodegeneration in a mouse model of glaucoma.

Howell GR, MacNicoll KH, Braine CE, Soto I, Macalinao DG, Sousa GL, John SW. Howell GR, et al. Neurobiol Dis. 2014 Nov;71:44-52. doi: 10.1016/j.nbd.2014.07.016. Epub 2014 Aug 15. Neurobiol Dis. 2014. PMID: 25132557 Free PMC article.

10

Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities.

Fernandes KA, Harder JM, Williams PA, Rausch RL, Kiernan AE, Nair KS, Anderson MG, John SW, Howell GR, Libby RT. Fernandes KA, et al. Exp Eye Res. 2015 Dec;141:42-56. doi: 10.1016/j.exer.2015.06.019. Epub 2015 Jun 24. Exp Eye Res. 2015. PMID: 26116903 Free PMC article. Review.

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