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Pressure-induced conformational switch of an interfacial protein.
Johnson QR, Lindsay RJ, Nellas RB, Shen T. Johnson QR, et al. Proteins. 2016 Jun;84(6):820-7. doi: 10.1002/prot.25031. Epub 2016 Apr 16. Proteins. 2016. PMID: 26967808
Statistical analysis of the ensemble of conformations also reveals the essential collective motions of the protein and how these motions contribute to gating. Arguments are presented as to why heightened sensitivity to high-pressure perturbation can be a general feature of …
Statistical analysis of the ensemble of conformations also reveals the essential collective motions of the protein and how these moti …
Assessment of a Plasma Amyloid Probability Score to Estimate Amyloid Positron Emission Tomography Findings Among Adults With Cognitive Impairment.
Hu Y, Kirmess KM, Meyer MR, Rabinovici GD, Gatsonis C, Siegel BA, Whitmer RA, Apgar C, Hanna L, Kanekiyo M, Kaplow J, Koyama A, Verbel D, Holubasch MS, Knapik SS, Connor J, Contois JH, Jackson EN, Harpstrite SE, Bateman RJ, Holtzman DM, Verghese PB, Fogelman I, Braunstein JB, Yarasheski KE, West T. Hu Y, et al. JAMA Netw Open. 2022 Apr 1;5(4):e228392. doi: 10.1001/jamanetworkopen.2022.8392. JAMA Netw Open. 2022. PMID: 35446396 Free PMC article.
DESIGN, SETTING, AND PARTICIPANTS: This cohort study includes analysis from 2 independent cross-sectional cohort studies: the discovery cohort of the Plasma Test for Amyloidosis Risk Screening (PARIS) study, a prospective add-on to the Imaging Dementia-Evidence for Amyloid Scanni …
DESIGN, SETTING, AND PARTICIPANTS: This cohort study includes analysis from 2 independent cross-sectional cohort studies: the discovery coho …