Jones B - Search Results

1

In vitro and in vivo glucuronidation of midazolam in humans.

Hyland R, Osborne T, Payne A, Kempshall S, Logan YR, Ezzeddine K, Jones B. Hyland R, et al. Among authors: jones b. Br J Clin Pharmacol. 2009 Apr;67(4):445-54. doi: 10.1111/j.1365-2125.2009.03386.x. Br J Clin Pharmacol. 2009. PMID: 19371318 Free PMC article.

2

Maraviroc: in vitro assessment of drug-drug interaction potential.

Hyland R, Dickins M, Collins C, Jones H, Jones B. Hyland R, et al. Among authors: jones h, jones b. Br J Clin Pharmacol. 2008 Oct;66(4):498-507. doi: 10.1111/j.1365-2125.2008.03198.x. Epub 2008 Apr 10. Br J Clin Pharmacol. 2008. PMID: 18647303 Free PMC article.

3

Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil.

Hyland R, Roe EG, Jones BC, Smith DA. Hyland R, et al. Among authors: jones bc. Br J Clin Pharmacol. 2001 Mar;51(3):239-48. doi: 10.1046/j.1365-2125.2001.00318.x. Br J Clin Pharmacol. 2001. PMID: 11298070 Free PMC article.

4

Investigation into UDP-glucuronosyltransferase (UGT) enzyme kinetics of imidazole- and triazole-containing antifungal drugs in human liver microsomes and recombinant UGT enzymes.

Bourcier K, Hyland R, Kempshall S, Jones R, Maximilien J, Irvine N, Jones B. Bourcier K, et al. Among authors: jones r, jones b. Drug Metab Dispos. 2010 Jun;38(6):923-9. doi: 10.1124/dmd.109.030676. Epub 2010 Mar 19. Drug Metab Dispos. 2010. PMID: 20304965

5

Utility of human/human-derived reagents in drug discovery and development: An industrial perspective.

Hyland R, Jones B, van de Waterbeemd H. Hyland R, et al. Among authors: jones b. Environ Toxicol Pharmacol. 2006 Feb;21(2):179-83. doi: 10.1016/j.etap.2005.07.007. Epub 2005 Aug 10. Environ Toxicol Pharmacol. 2006. PMID: 21783655

6

Identification of the cytochrome P450 enzymes involved in the N-oxidation of voriconazole.

Hyland R, Jones BC, Smith DA. Hyland R, et al. Among authors: jones bc. Drug Metab Dispos. 2003 May;31(5):540-7. doi: 10.1124/dmd.31.5.540. Drug Metab Dispos. 2003. PMID: 12695341

7

Significance of metabolism in the disposition and action of the antidysrhythmic drug, dofetilide. In vitro studies and correlation with in vivo data.

Walker DK, Alabaster CT, Congrave GS, Hargreaves MB, Hyland R, Jones BC, Reed LJ, Smith DA. Walker DK, et al. Among authors: jones bc. Drug Metab Dispos. 1996 Apr;24(4):447-55. Drug Metab Dispos. 1996. PMID: 8801060

8

Induction of cytochrome P450: assessment in an immortalized human hepatocyte cell line (Fa2N4) using a novel higher throughput cocktail assay.

Youdim KA, Tyman CA, Jones BC, Hyland R. Youdim KA, et al. Drug Metab Dispos. 2007 Feb;35(2):275-82. doi: 10.1124/dmd.106.012864. Epub 2006 Nov 15. Drug Metab Dispos. 2007. PMID: 17108058

9

Interaction of terfenadine and its primary metabolites with cytochrome P450 2D6.

Jones BC, Hyland R, Ackland M, Tyman CA, Smith DA. Jones BC, et al. Drug Metab Dispos. 1998 Sep;26(9):875-82. Drug Metab Dispos. 1998. PMID: 9733666

10

Human cytochrome P450s: selectivity and measurement in vivo.

Smith DA, Abel SM, Hyland R, Jones BC. Smith DA, et al. Among authors: jones bc. Xenobiotica. 1998 Dec;28(12):1095-128. doi: 10.1080/004982598238859. Xenobiotica. 1998. PMID: 9890156 Review. No abstract available.

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