Jost C - Search Results

1

Engineered proteins with desired specificity: DARPins, other alternative scaffolds and bispecific IgGs.

Jost C, Plückthun A. Jost C, et al. Curr Opin Struct Biol. 2014 Aug;27:102-12. doi: 10.1016/j.sbi.2014.05.011. Epub 2014 Jul 15. Curr Opin Struct Biol. 2014. PMID: 25033247 Review.

2

Structural basis for eliciting a cytotoxic effect in HER2-overexpressing cancer cells via binding to the extracellular domain of HER2.

Jost C, Schilling J, Tamaskovic R, Schwill M, Honegger A, Plückthun A. Jost C, et al. Structure. 2013 Nov 5;21(11):1979-91. doi: 10.1016/j.str.2013.08.020. Epub 2013 Oct 3. Structure. 2013. PMID: 24095059 Free article.

3

Rigidity of the extracellular part of HER2: Evidence from engineering subdomain interfaces and shared-helix DARPin-DARPin fusions.

Jost C, Stüber JC, Honegger A, Wu Y, Batyuk A, Plückthun A. Jost C, et al. Protein Sci. 2017 Sep;26(9):1796-1806. doi: 10.1002/pro.3216. Epub 2017 Jul 5. Protein Sci. 2017. PMID: 28639341 Free PMC article.

4

Intermolecular biparatopic trapping of ErbB2 prevents compensatory activation of PI3K/AKT via RAS-p110 crosstalk.

Tamaskovic R, Schwill M, Nagy-Davidescu G, Jost C, Schaefer DC, Verdurmen WP, Schaefer JV, Honegger A, Plückthun A. Tamaskovic R, et al. Among authors: jost c. Nat Commun. 2016 Jun 3;7:11672. doi: 10.1038/ncomms11672. Nat Commun. 2016. PMID: 27255951 Free PMC article.

5

DARPins: an efficient targeting domain for lentiviral vectors.

Münch RC, Mühlebach MD, Schaser T, Kneissl S, Jost C, Plückthun A, Cichutek K, Buchholz CJ. Münch RC, et al. Among authors: jost c. Mol Ther. 2011 Apr;19(4):686-93. doi: 10.1038/mt.2010.298. Epub 2011 Jan 11. Mol Ther. 2011. PMID: 21224833 Free PMC article.

6

Protein tag-mediated conjugation of oligonucleotides to recombinant affinity binders for proximity ligation.

Gu GJ, Friedman M, Jost C, Johnsson K, Kamali-Moghaddam M, Plückthun A, Landegren U, Söderberg O. Gu GJ, et al. Among authors: jost c. N Biotechnol. 2013 Jan 25;30(2):144-52. doi: 10.1016/j.nbt.2012.05.005. Epub 2012 Jun 2. N Biotechnol. 2013. PMID: 22664266 Free article.

7

A universal approach to prepare reagents for DNA-assisted protein analysis.

Yan J, Gu GJ, Jost C, Hammond M, Plückthun A, Landegren U, Kamali-Moghaddam M. Yan J, et al. Among authors: jost c. PLoS One. 2014 Sep 18;9(9):e108061. doi: 10.1371/journal.pone.0108061. eCollection 2014. PLoS One. 2014. PMID: 25233463 Free PMC article.

8

Enhanced lysis by bispecific oncolytic measles viruses simultaneously using HER2/neu or EpCAM as target receptors.

Hanauer JR, Gottschlich L, Riehl D, Rusch T, Koch V, Friedrich K, Hutzler S, Prüfer S, Friedel T, Hanschmann KM, Münch RC, Jost C, Plückthun A, Cichutek K, Buchholz CJ, Mühlebach MD. Hanauer JR, et al. Among authors: jost c. Mol Ther Oncolytics. 2016 Feb 24;3:16003. doi: 10.1038/mto.2016.3. eCollection 2016. Mol Ther Oncolytics. 2016. PMID: 27119117 Free PMC article.

9

Direct identification of ligand-receptor interactions on living cells and tissues.

Frei AP, Jeon OY, Kilcher S, Moest H, Henning LM, Jost C, Plückthun A, Mercer J, Aebersold R, Carreira EM, Wollscheid B. Frei AP, et al. Among authors: jost c. Nat Biotechnol. 2012 Oct;30(10):997-1001. doi: 10.1038/nbt.2354. Epub 2012 Sep 16. Nat Biotechnol. 2012. PMID: 22983091

10

Structural model for the interaction of a designed Ankyrin Repeat Protein with the human epidermal growth factor receptor 2.

Epa VC, Dolezal O, Doughty L, Xiao X, Jost C, Plückthun A, Adams TE. Epa VC, et al. Among authors: jost c. PLoS One. 2013;8(3):e59163. doi: 10.1371/journal.pone.0059163. Epub 2013 Mar 19. PLoS One. 2013. PMID: 23527120 Free PMC article.

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