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A phase I trial of the selective oral cyclin-dependent kinase inhibitor seliciclib (CYC202; R-Roscovitine), administered twice daily for 7 days every 21 days.
Benson C, White J, De Bono J, O'Donnell A, Raynaud F, Cruickshank C, McGrath H, Walton M, Workman P, Kaye S, Cassidy J, Gianella-Borradori A, Judson I, Twelves C. Benson C, et al. Among authors: judson i. Br J Cancer. 2007 Jan 15;96(1):29-37. doi: 10.1038/sj.bjc.6603509. Epub 2006 Dec 19. Br J Cancer. 2007. PMID: 17179992 Free PMC article. Clinical Trial.
Phase I study of oral JM216 given twice daily.
Beale P, Raynaud F, Hanwell J, Berry C, Moore S, Odell D, Judson I. Beale P, et al. Among authors: judson i. Cancer Chemother Pharmacol. 1998;42(2):142-8. doi: 10.1007/s002800050797. Cancer Chemother Pharmacol. 1998. PMID: 9654114 Clinical Trial.
A Phase I study of the angiogenesis inhibitor SU5416 (semaxanib) in solid tumours, incorporating dynamic contrast MR pharmacodynamic end points.
O'Donnell A, Padhani A, Hayes C, Kakkar AJ, Leach M, Trigo JM, Scurr M, Raynaud F, Phillips S, Aherne W, Hardcastle A, Workman P, Hannah A, Judson I. O'Donnell A, et al. Among authors: judson i. Br J Cancer. 2005 Oct 17;93(8):876-83. doi: 10.1038/sj.bjc.6602797. Br J Cancer. 2005. PMID: 16222321 Free PMC article. Clinical Trial.
Phase I trial outcomes in older patients with advanced solid tumours.
Khan KH, Yap TA, Ring A, Molife LR, Bodla S, Thomas K, Zivi A, Smith A, Judson I, Banerji U, de Bono JS, Kaye SB. Khan KH, et al. Among authors: judson i. Br J Cancer. 2016 Feb 2;114(3):262-8. doi: 10.1038/bjc.2015.477. Epub 2016 Jan 12. Br J Cancer. 2016. PMID: 26757260 Free PMC article.
391 results