Judson IR - Search Results

1

The in vivo metabolic stability of dipeptide analogues of the quinazoline antifolate, ICI 198583, in mice.

Jodrell DI, Gibson W, Bisset GM, Boyle FT, Judson IR, Jackman AL. Jodrell DI, et al. Among authors: judson ir. Biochem Pharmacol. 1993 Dec 14;46(12):2229-34. doi: 10.1016/0006-2952(93)90613-2. Biochem Pharmacol. 1993. PMID: 8274156

2

The measurement of polyglutamate metabolites of the thymidylate synthase inhibitor, ICI D1694, in mouse and human cultured cells.

Gibson W, Bisset GM, Marsham PR, Kelland LR, Judson IR, Jackman AL. Gibson W, et al. Among authors: judson ir. Biochem Pharmacol. 1993 Feb 24;45(4):863-9. doi: 10.1016/0006-2952(93)90170-2. Biochem Pharmacol. 1993. PMID: 7680860

3

The history of the development and clinical use of CB 3717 and ICI D1694.

Clarke SJ, Jackman AL, Judson IR. Clarke SJ, et al. Among authors: judson ir. Adv Exp Med Biol. 1993;339:277-87; discussion 289-90. doi: 10.1007/978-1-4615-2488-5_27. Adv Exp Med Biol. 1993. PMID: 8178723

4

ICI D1694, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo: a new agent for clinical study.

Jackman AL, Taylor GA, Gibson W, Kimbell R, Brown M, Calvert AH, Judson IR, Hughes LR. Jackman AL, et al. Among authors: judson ir. Cancer Res. 1991 Oct 15;51(20):5579-86. Cancer Res. 1991. PMID: 1913676

5

Recent preclinical and clinical studies with the thymidylate synthase inhibitor N10-propargyl-5,8-dideazafolic acid (CB 3717).

Calvert AH, Newell DR, Jackman AL, Gumbrell LA, Sikora E, Grzelakowska-Sztabert B, Bishop JA, Judson IR, Harland SJ, Harrap KR. Calvert AH, et al. Among authors: judson ir. NCI Monogr. 1987;(5):213-8. NCI Monogr. 1987. PMID: 3431591

6

The toxicity of ICI D1694 in man and mouse.

Clarke SJ, Jackman AL, Judson IR. Clarke SJ, et al. Among authors: judson ir. Adv Exp Med Biol. 1993;338:601-4. doi: 10.1007/978-1-4615-2960-6_123. Adv Exp Med Biol. 1993. PMID: 8304190 Clinical Trial. No abstract available.

7

Phase I trial of ZD1694, a new folate-based thymidylate synthase inhibitor, in patients with solid tumors.

Clarke SJ, Hanwell J, de Boer M, Planting A, Verweij J, Walker M, Smith R, Jackman AL, Hughes LR, Harrap KR, Kennealey GT, Judson IR. Clarke SJ, et al. Among authors: judson ir. J Clin Oncol. 1996 May;14(5):1495-503. doi: 10.1200/JCO.1996.14.5.1495. J Clin Oncol. 1996. PMID: 8622063 Clinical Trial.

8

Re: "Oncology drug discovery and clinical trial testing: who's listening?".

Jackman A, Judson I. Jackman A, et al. Cancer Invest. 1994;12(1):105-8. doi: 10.3109/07357909409021400. Cancer Invest. 1994. PMID: 8281460 No abstract available.

9

An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models.

Banerji U, Sain N, Sharp SY, Valenti M, Asad Y, Ruddle R, Raynaud F, Walton M, Eccles SA, Judson I, Jackman AL, Workman P. Banerji U, et al. Cancer Chemother Pharmacol. 2008 Oct;62(5):769-78. doi: 10.1007/s00280-007-0662-x. Epub 2008 Jan 10. Cancer Chemother Pharmacol. 2008. PMID: 18193424

10

Patterns of elevation of plasma 2'-deoxyuridine, a surrogate marker of thymidylate synthase (TS) inhibition, after administration of two different schedules of 5-fluorouracil and the specific TS inhibitors raltitrexed (Tomudex) and ZD9331.

Ford HE, Mitchell F, Cunningham D, Farrugia DC, Hill ME, Rees C, Calvert AH, Judson IR, Jackman AL. Ford HE, et al. Among authors: judson ir. Clin Cancer Res. 2002 Jan;8(1):103-9. Clin Cancer Res. 2002. PMID: 11801545 Clinical Trial.

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