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Page 1
Shifting landscapes of human MTHFR missense-variant effects.
Am J Hum Genet. 2021 Jul 1;108(7):1283-1300. doi: 10.1016/j.ajhg.2021.05.009.
Am J Hum Genet. 2021.
PMID: 34214447
Free PMC article.
A proactive genotype-to-patient-phenotype map for cystathionine beta-synthase.
Sun S, Weile J, Verby M, Wu Y, Wang Y, Cote AG, Fotiadou I, Kitaygorodsky J, Vidal M, Rine J, Ješina P, Kožich V, Roth FP.
Sun S, et al. Among authors: kitaygorodsky j.
Genome Med. 2020 Jan 30;12(1):13. doi: 10.1186/s13073-020-0711-1.
Genome Med. 2020.
PMID: 32000841
Free PMC article.
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Functional characterization of a PROTAC directed against BRAF mutant V600E.
Posternak G, Tang X, Maisonneuve P, Jin T, Lavoie H, Daou S, Orlicky S, Goullet de Rugy T, Caldwell L, Chan K, Aman A, Prakesch M, Poda G, Mader P, Wong C, Maier S, Kitaygorodsky J, Larsen B, Colwill K, Yin Z, Ceccarelli DF, Batey RA, Taipale M, Kurinov I, Uehling D, Wrana J, Durocher D, Gingras AC, Al-Awar R, Therrien M, Sicheri F.
Posternak G, et al. Among authors: kitaygorodsky j.
Nat Chem Biol. 2020 Nov;16(11):1170-1178. doi: 10.1038/s41589-020-0609-7. Epub 2020 Aug 10.
Nat Chem Biol. 2020.
PMID: 32778845
Free PMC article.
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Accelerated waning of immunity to SARS-CoV-2 mRNA vaccines in patients with immune-mediated inflammatory diseases.
Dayam RM, Law JC, Goetgebuer RL, Chao GY, Abe KT, Sutton M, Finkelstein N, Stempak JM, Pereira D, Croitoru D, Acheampong L, Rizwan S, Rymaszewski K, Milgrom R, Ganatra D, Batista NV, Girard M, Lau I, Law R, Cheung MW, Rathod B, Kitaygorodsky J, Samson R, Hu Q, Hardy WR, Haroon N, Inman RD, Piguet V, Chandran V, Silverberg MS, Gingras AC, Watts TH.
Dayam RM, et al. Among authors: kitaygorodsky j.
JCI Insight. 2022 Jun 8;7(11):e159721. doi: 10.1172/jci.insight.159721.
JCI Insight. 2022.
PMID: 35471956
Free PMC article.
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The HisRS-like domain of GCN2 is a pseudoenzyme that can bind uncharged tRNA.
Yin JZ, Keszei AFA, Houliston S, Filandr F, Beenstock J, Daou S, Kitaygorodsky J, Schriemer DC, Mazhab-Jafari MT, Gingras AC, Sicheri F.
Yin JZ, et al. Among authors: kitaygorodsky j.
Structure. 2024 Mar 22:S0969-2126(24)00081-9. doi: 10.1016/j.str.2024.02.021. Online ahead of print.
Structure. 2024.
PMID: 38531363
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Risk factors for development of dementia in a unique six-year cohort study. I. An exploratory, pilot study of involvement of the E4 allele of apolipoprotein E, mutations of the hemochromatosis-HFE gene, type 2 diabetes, and stroke.
Percy M, Somerville MJ, Hicks M, Garcia A, Colelli T, Wright E, Kitaygorodsky J, Jiang A, Ho V, Parpia A, Wong MK.
Percy M, et al. Among authors: kitaygorodsky j.
J Alzheimers Dis. 2014;38(4):907-22. doi: 10.3233/JAD-131409.
J Alzheimers Dis. 2014.
PMID: 24081379
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