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Liposome-siRNA-peptide complexes cross the blood-brain barrier and significantly decrease PrP on neuronal cells and PrP in infected cell cultures.
Pulford B, Reim N, Bell A, Veatch J, Forster G, Bender H, Meyerett C, Hafeman S, Michel B, Johnson T, Wyckoff AC, Miele G, Julius C, Kranich J, Schenkel A, Dow S, Zabel MD. Pulford B, et al. Among authors: julius c. PLoS One. 2010 Jun 14;5(6):e11085. doi: 10.1371/journal.pone.0011085. PLoS One. 2010. PMID: 20559428 Free PMC article.
Transcriptional stability of cultured cells upon prion infection.
Julius C, Hutter G, Wagner U, Seeger H, Kana V, Kranich J, Klöhn PC, Weissmann C, Miele G, Aguzzi A. Julius C, et al. J Mol Biol. 2008 Feb 1;375(5):1222-33. doi: 10.1016/j.jmb.2007.11.003. Epub 2007 Nov 12. J Mol Biol. 2008. PMID: 18082765
Prions and peripheral nerves: a deadly rendezvous.
Heikenwalder M, Julius C, Aguzzi A. Heikenwalder M, et al. Among authors: julius c. J Neurosci Res. 2007 Sep;85(12):2714-25. doi: 10.1002/jnr.21246. J Neurosci Res. 2007. PMID: 17393538 Review.
A versatile prion replication assay in organotypic brain slices.
Falsig J, Julius C, Margalith I, Schwarz P, Heppner FL, Aguzzi A. Falsig J, et al. Among authors: julius c. Nat Neurosci. 2008 Jan;11(1):109-17. doi: 10.1038/nn2028. Epub 2007 Dec 9. Nat Neurosci. 2008. PMID: 18066056 Free PMC article.
De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis.
Sigurdson CJ, Nilsson KP, Hornemann S, Heikenwalder M, Manco G, Schwarz P, Ott D, Rülicke T, Liberski PP, Julius C, Falsig J, Stitz L, Wüthrich K, Aguzzi A. Sigurdson CJ, et al. Among authors: julius c. Proc Natl Acad Sci U S A. 2009 Jan 6;106(1):304-9. doi: 10.1073/pnas.0810680105. Epub 2008 Dec 10. Proc Natl Acad Sci U S A. 2009. PMID: 19073920 Free PMC article.
Prion strain discrimination in cell culture: the cell panel assay.
Mahal SP, Baker CA, Demczyk CA, Smith EW, Julius C, Weissmann C. Mahal SP, et al. Among authors: julius c. Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20908-13. doi: 10.1073/pnas.0710054104. Epub 2007 Dec 11. Proc Natl Acad Sci U S A. 2007. PMID: 18077360 Free PMC article.
45 results