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Induction of microtubule-damage, mitotic arrest, Bcl-2 phosphorylation, Bak activation, and mitochondria-dependent caspase cascade is involved in human Jurkat T-cell apoptosis by aruncin B from Aruncus dioicus var. kamtschaticus.
Han CR, Jun do Y, Woo HJ, Jeong SY, Woo MH, Kim YH. Han CR, et al. Among authors: jun do y. Bioorg Med Chem Lett. 2012 Jan 15;22(2):945-53. doi: 10.1016/j.bmcl.2011.12.023. Epub 2011 Dec 9. Bioorg Med Chem Lett. 2012. PMID: 22197393
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