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Safe and targeted anticancer efficacy of a novel class of antioxidant-conjugated difluorodiarylidenyl piperidones: differential cytotoxicity in healthy and cancer cells.
Selvendiran K, Ahmed S, Dayton A, Kuppusamy ML, Tazi M, Bratasz A, Tong L, Rivera BK, Kálai T, Hideg K, Kuppusamy P. Selvendiran K, et al. Among authors: kalai t. Free Radic Biol Med. 2010 May 1;48(9):1228-35. doi: 10.1016/j.freeradbiomed.2010.02.009. Epub 2010 Feb 12. Free Radic Biol Med. 2010. PMID: 20156552 Free PMC article.
HO-3867, a synthetic compound, inhibits the migration and invasion of ovarian carcinoma cells through downregulation of fatty acid synthase and focal adhesion kinase.
Selvendiran K, Ahmed S, Dayton A, Ravi Y, Kuppusamy ML, Bratasz A, Rivera BK, Kálai T, Hideg K, Kuppusamy P. Selvendiran K, et al. Among authors: kalai t. Mol Cancer Res. 2010 Sep;8(9):1188-97. doi: 10.1158/1541-7786.MCR-10-0201. Epub 2010 Aug 16. Mol Cancer Res. 2010. PMID: 20713491 Free PMC article.
Cardioprotection by HO-4038, a novel verapamil derivative, targeted against ischemia and reperfusion-mediated acute myocardial infarction.
Mohan IK, Khan M, Wisel S, Selvendiran K, Sridhar A, Carnes CA, Bognar B, Kálai T, Hideg K, Kuppusamy P. Mohan IK, et al. Among authors: kalai t. Am J Physiol Heart Circ Physiol. 2009 Jan;296(1):H140-51. doi: 10.1152/ajpheart.00687.2008. Epub 2008 Oct 31. Am J Physiol Heart Circ Physiol. 2009. PMID: 18978191 Free PMC article.
Synthesis of N-substituted 3,5-bis(arylidene)-4-piperidones with high antitumor and antioxidant activity.
Kálai T, Kuppusamy ML, Balog M, Selvendiran K, Rivera BK, Kuppusamy P, Hideg K. Kálai T, et al. J Med Chem. 2011 Aug 11;54(15):5414-21. doi: 10.1021/jm200353f. Epub 2011 Jul 6. J Med Chem. 2011. PMID: 21702507
.; Kuppusamy, L. M.; Ahmed, S.; Ravi, Y.; Trigg, N. J.; Rivera, B. K.; Kalai, T.; Hideg, K.; Kuppusamy, P. Mol. Cancer Ther. 2010, 9, 1169-1179), 5e, 7, 9) showed limited toxicity toward noncancerous cell lines. ...
.; Kuppusamy, L. M.; Ahmed, S.; Ravi, Y.; Trigg, N. J.; Rivera, B. K.; Kalai, T.; Hideg, K.; Kuppusamy, P. Mol. Cancer Ther. 2 …
93 results