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Diminished PLK2 Induces Cardiac Fibrosis and Promotes Atrial Fibrillation.
Künzel SR, Hoffmann M, Weber S, Künzel K, Kämmerer S, Günscht M, Klapproth E, Rausch JSE, Sadek MS, Kolanowski T, Meyer-Roxlau S, Piorkowski C, Tugtekin SM, Rose-John S, Yin X, Mayr M, Kuhlmann JD, Wimberger P, Grützmann K, Herzog N, Küpper JH, O'Reilly M, Kabir SN, Sommerfeld LC, Guan K, Wielockx B, Fabritz L, Nattel S, Ravens U, Dobrev D, Wagner M, El-Armouche A. Künzel SR, et al. Among authors: kunzel k. Circ Res. 2021 Oct;129(8):804-820. doi: 10.1161/CIRCRESAHA.121.319425. Epub 2021 Aug 26. Circ Res. 2021. PMID: 34433292 Free PMC article.
Systemic mesalazine treatment prevents spontaneous skin fibrosis in PLK2-deficient mice.
Newe M, Kant TA, Hoffmann M, Rausch JSE, Winter L, Künzel K, Klapproth E, Günther C, Künzel SR. Newe M, et al. Among authors: kunzel k. Naunyn Schmiedebergs Arch Pharmacol. 2021 Nov;394(11):2233-2244. doi: 10.1007/s00210-021-02135-w. Epub 2021 Aug 19. Naunyn Schmiedebergs Arch Pharmacol. 2021. PMID: 34410453 Free PMC article.
Repurposing mesalazine against cardiac fibrosis in vitro.
Hoffmann M, Kant TA, Emig R, Rausch JSE, Newe M, Schubert M, Künzel K, Winter L, Klapproth E, Peyronnet R, Ravens U, El-Armouche A, Künzel SR. Hoffmann M, et al. Among authors: kunzel k. Naunyn Schmiedebergs Arch Pharmacol. 2021 Mar;394(3):533-543. doi: 10.1007/s00210-020-01998-9. Epub 2020 Oct 16. Naunyn Schmiedebergs Arch Pharmacol. 2021. PMID: 33064167 Free PMC article.
Modeling atrial fibrosis in vitro-Generation and characterization of a novel human atrial fibroblast cell line.
Künzel SR, Rausch JSE, Schäffer C, Hoffmann M, Künzel K, Klapproth E, Kant T, Herzog N, Küpper JH, Lorenz K, Dudek S, Emig R, Ravens U, Rog-Zielinska EA, Peyronnet R, El-Armouche A. Künzel SR, et al. Among authors: kunzel k. FEBS Open Bio. 2020 Jul;10(7):1210-1218. doi: 10.1002/2211-5463.12896. Epub 2020 Jun 2. FEBS Open Bio. 2020. PMID: 32421922 Free PMC article.
36 results