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2017 2
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2020 1
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2023 1
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EWS::FLI1 and HOXD13 Control Tumor Cell Plasticity in Ewing Sarcoma.
Apfelbaum AA, Wu F, Hawkins AG, Magnuson B, Jiménez JA, Taylor SD, Wrenn ED, Waltner O, Pfaltzgraff ER, Song JY, Hall C, Wellik DM, Ljungman M, Furlan SN, Ryan RJH, Sarthy JF, Lawlor ER. Apfelbaum AA, et al. Clin Cancer Res. 2022 Oct 14;28(20):4466-4478. doi: 10.1158/1078-0432.CCR-22-0384. Clin Cancer Res. 2022. PMID: 35653119 Free PMC article.
Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain.
Shukla S, Ying W, Gray F, Yao Y, Simes ML, Zhao Q, Miao H, Cho HJ, González-Alonso P, Winkler A, Lund G, Purohit T, Kim E, Zhang X, Ray JM, He S, Nikolaidis C, Ndoj J, Wang J, Jaremko Ł, Jaremko M, Ryan RJH, Guzman ML, Grembecka J, Cierpicki T. Shukla S, et al. Nat Chem Biol. 2021 Jul;17(7):784-793. doi: 10.1038/s41589-021-00815-5. Epub 2021 Jun 21. Nat Chem Biol. 2021. PMID: 34155404 Free PMC article.
Simultaneous Identification of Cell of Origin, Translocations, and Hotspot Mutations in Diffuse Large B-Cell Lymphoma Using a Single RNA-Sequencing Assay.
Crotty R, Hu K, Stevenson K, Pontius MY, Sohani AR, Ryan RJH, Rueckert E, Brauer HA, Hudson B, Berlin AM, Rodenbaugh M, Licon A, Haimes J, Iafrate AJ, Nardi V, Louissaint A. Crotty R, et al. Am J Clin Pathol. 2021 Apr 26;155(5):748-754. doi: 10.1093/ajcp/aqaa185. Am J Clin Pathol. 2021. PMID: 33258912 Free PMC article.
Combinatorial ETS1-dependent control of oncogenic NOTCH1 enhancers in T-cell leukemia.
McCarter AC, Della Gatta G, Melnick A, Kim E, Sha C, Wang Q, Nalamolu JK, Liu Y, Keeley TM, Yan R, Sun M, Kodgule R, Kunnath N, Ambesi-Impiombato A, Kuick R, Rao A, Ryan RJH, Kee BL, Samuelson LC, Ostrowski MC, Ferrando AA, Chiang MY. McCarter AC, et al. Blood Cancer Discov. 2020 Sep;1(2):178-197. doi: 10.1158/2643-3230.BCD-20-0026. Blood Cancer Discov. 2020. PMID: 32924017 Free PMC article.
Mouse DCUN1D1 (SCCRO) is required for spermatogenetic individualization.
Huang G, Kaufman AJ, Ryan RJH, Romin Y, Huryn L, Bains S, Manova-Todorova K, Morris PL, Hunnicutt GR, Adelman CA, Petrini JHJ, Ramanathan Y, Singh B. Huang G, et al. PLoS One. 2019 Jan 17;14(1):e0209995. doi: 10.1371/journal.pone.0209995. eCollection 2019. PLoS One. 2019. PMID: 30653527 Free PMC article.
A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas.
Ryan RJH, Petrovic J, Rausch DM, Zhou Y, Lareau CA, Kluk MJ, Christie AL, Lee WY, Tarjan DR, Guo B, Donohue LKH, Gillespie SM, Nardi V, Hochberg EP, Blacklow SC, Weinstock DM, Faryabi RB, Bernstein BE, Aster JC, Pear WS. Ryan RJH, et al. Cell Rep. 2017 Oct 17;21(3):784-797. doi: 10.1016/j.celrep.2017.09.066. Cell Rep. 2017. PMID: 29045844 Free PMC article.
A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression.
Gupta RM, Hadaya J, Trehan A, Zekavat SM, Roselli C, Klarin D, Emdin CA, Hilvering CRE, Bianchi V, Mueller C, Khera AV, Ryan RJH, Engreitz JM, Issner R, Shoresh N, Epstein CB, de Laat W, Brown JD, Schnabel RB, Bernstein BE, Kathiresan S. Gupta RM, et al. Cell. 2017 Jul 27;170(3):522-533.e15. doi: 10.1016/j.cell.2017.06.049. Cell. 2017. PMID: 28753427 Free PMC article.