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Year Number of Results
2004 2
2005 4
2006 2
2012 1
2018 1
2019 2
2021 1
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12 results

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Page 1
Genetic variants in the Hedgehog signaling pathway genes are associated with gastric cancer risk in a Chinese Han population.
Zhang Y, Lu K, Wu X, Liu H, Xin J, Wang X, Gong W, Zhao Q, Wang M, Chu H, Du M, Tao G, Zhang Z. Zhang Y, et al. J Biomed Res. 2021 Oct 29;36(1):22-31. doi: 10.7555/JBR.35.20210091. J Biomed Res. 2021. PMID: 35403607 Free PMC article.
The Hedgehog signaling pathway participates in the occurrence and progression of cancers including gastric cancer. We conducted this study to evaluate whether genetic variants in the Hedgehog signaling pathway genes would affect gastric cancer risk. ...The ex …
The Hedgehog signaling pathway participates in the occurrence and progression of cancers including gastric cancer. We conducte …
Hedgehog signaling pathway and gastric cancer.
Katoh Y, Katoh M. Katoh Y, et al. Cancer Biol Ther. 2005 Oct;4(10):1050-4. doi: 10.4161/cbt.4.10.2184. Epub 2005 Oct 18. Cancer Biol Ther. 2005. PMID: 16258256 Review.
Aberrant activation of Hedgehog signaling pathway leads to pathological consequences in a variety of human tumors, such as gastric cancer and pancreatic cancer. Endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), surgical gastrectomy and chem …
Aberrant activation of Hedgehog signaling pathway leads to pathological consequences in a variety of human tumors, such as gastric cancer …
Characterization of KIF7 gene in silico.
Katoh Y, Katoh M. Katoh Y, et al. Int J Oncol. 2004 Dec;25(6):1881-6. Int J Oncol. 2004. PMID: 15547730
KIF27 is one of the mammalian orthologs for Drosophila Cos2. KIF7 gene is the paralog of KIF27 gene; however, complete coding sequence (CDS) of KIF7 remains elusive. ...Human KIF7 showed 43.6% total-amino-acid identity with human KIF27. Kinesin motor catalyti …
KIF27 is one of the mammalian orthologs for Drosophila Cos2. KIF7 gene is the paralog of KIF27 gene; however, complete coding …
KIF27 is one of orthologs for Drosophila Costal-2.
Katoh Y, Katoh M. Katoh Y, et al. Int J Oncol. 2004 Dec;25(6):1875-80. Int J Oncol. 2004. PMID: 15547729
Phylogenetic analysis revealed that KIF27, Kif7, KIF4A, KIF4B and KIF21A constitute the KIF27 subfamily among mammalian Kinesin family. ...These facts indicate that KIF27 is one of mammalian orthologs for Drosophila Cos2....
Phylogenetic analysis revealed that KIF27, Kif7, KIF4A, KIF4B and KIF21A constitute the KIF27 subfamily among mammalian Kinesi …
Hedgehog signaling pathway and gastrointestinal stem cell signaling network (review).
Katoh Y, Katoh M. Katoh Y, et al. Int J Mol Med. 2006 Dec;18(6):1019-23. Int J Mol Med. 2006. PMID: 17089004 Review.
Hedgehog signals from epithelial cells then induces FOXL1-mediated BMP4 upregulation in mesenchymal cells. Hedgehog signaling is frequently activated in esophageal cancer, gastric cancer and pancreatic cancer due to transcriptional upregulation of Hedgehog li …
Hedgehog signals from epithelial cells then induces FOXL1-mediated BMP4 upregulation in mesenchymal cells. Hedgehog signaling is frequently …
High-Density Cell Arrays for Genome-Scale Phenotypic Screening.
Starkuviene V, Kallenberger SM, Beil N, Lisauskas T, Schumacher BS, Bulkescher R, Wajda P, Gunkel M, Beneke J, Erfle H. Starkuviene V, et al. SLAS Discov. 2019 Mar;24(3):274-283. doi: 10.1177/2472555218818757. Epub 2019 Jan 25. SLAS Discov. 2019. PMID: 30682322 Free article.
Structural insights into human Kif7, a kinesin involved in Hedgehog signalling.
Klejnot M, Kozielski F. Klejnot M, et al. Acta Crystallogr D Biol Crystallogr. 2012 Feb;68(Pt 2):154-9. doi: 10.1107/S0907444911053042. Epub 2012 Jan 13. Acta Crystallogr D Biol Crystallogr. 2012. PMID: 22281744 Free PMC article.
It is also involved in primary cilium formation and the Hedgehog signalling pathway and may play a role in cancer. Its activity is crucial for embryonic development. Kif7 and Kif27, a closely related kinesin in the same subfamily, are orthologues of the Drosophila m …
It is also involved in primary cilium formation and the Hedgehog signalling pathway and may play a role in cancer. Its activity is cr …
Characterization of KIF12 gene in silico.
Katoh M, Katoh M. Katoh M, et al. Oncol Rep. 2005 Feb;13(2):367-70. Oncol Rep. 2005. PMID: 15643526
KIF proteins produce forces by using the energy from ATP hydrolysis within the KISc domain. We have recently identified that KIF27 is one of mammalian orthologs for Drosophila Costal-2 (Cos2), functioning as regulator of Hedgehog signaling pathway. ...KIF12 mRNA was expres …
KIF proteins produce forces by using the energy from ATP hydrolysis within the KISc domain. We have recently identified that KIF27 is …
Comparative genomics on Sonic hedgehog orthologs.
Katoh Y, Katoh M. Katoh Y, et al. Oncol Rep. 2005 Oct;14(4):1087-90. Oncol Rep. 2005. PMID: 16142377
Soluble Hedgehog ligands bind to Patched receptor to activate Smoothened seven-transmembrane receptor with Frizzled domain. KIF27 and KIF7 are human homologs of Drosophila Costal-2 (Cos2), associating with Smoothened, GLI homolog, Fused, and microtubule. ...Human SHH mRNA …
Soluble Hedgehog ligands bind to Patched receptor to activate Smoothened seven-transmembrane receptor with Frizzled domain. KIF27 and …
Delineation of the minimal commonly deleted segment and identification of candidate tumor-suppressor genes in del(9q) acute myeloid leukemia.
Sweetser DA, Peniket AJ, Haaland C, Blomberg AA, Zhang Y, Zaidi ST, Dayyani F, Zhao Z, Heerema NA, Boultwood J, Dewald GW, Paietta E, Slovak ML, Willman CL, Wainscoat JS, Bernstein ID, Daly SB. Sweetser DA, et al. Genes Chromosomes Cancer. 2005 Nov;44(3):279-91. doi: 10.1002/gcc.20236. Genes Chromosomes Cancer. 2005. PMID: 16015647
We found no homozygous loss at any locus tested. The CDR contains 7 known genes, FRMD3, UBQLN1, GKAP42, KIF27, HNRPK, SLC28A3, and NTRK2, and 4 novel genes, RASEF, C9orf103, C9orf64, and C9orf76. ...
We found no homozygous loss at any locus tested. The CDR contains 7 known genes, FRMD3, UBQLN1, GKAP42, KIF27, HNRPK, SLC28A3, and NT …
12 results