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Year Number of Results
1999 1
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123 results

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Analysis of expression and prognosis of KLK7 in ovarian cancer.
Chen E, Zhu H, Yang Y, Wang L, Zhang J, Han Y, Liu X. Chen E, et al. Open Med (Wars). 2020 Sep 30;15(1):932-939. doi: 10.1515/med-2020-0139. eCollection 2020. Open Med (Wars). 2020. PMID: 33336051 Free PMC article.
MATERIALS AND METHODS: The expression of KLK7 in human ovarian cancer was evaluated by Oncomine and Cancer Cell Line Encyclopedia database. ...RESULTS: It was found that the expression of KLK7 was higher in ovarian cancer compared with other typ …
MATERIALS AND METHODS: The expression of KLK7 in human ovarian cancer was evaluated by Oncomine and Cancer Cell Line En …
Prognostic value of kallikrein-related peptidase 7 (KLK7) mRNA expression in advanced high-grade serous ovarian cancer.
Gong W, Liu Y, Diamandis EP, Kiechle M, Bronger H, Dorn J, Dreyer T, Magdolen V. Gong W, et al. J Ovarian Res. 2020 Oct 21;13(1):125. doi: 10.1186/s13048-020-00725-5. J Ovarian Res. 2020. PMID: 33087135 Free PMC article.
A growing body of evidence suggests tumor-supporting roles of several members of the kallikrein-related peptidase (KLK) family, including KLK5 and KLK7, in this cancer subtype. In normal physiology, KLK5 and KLK7 are the major proteases involved in skin desqu …
A growing body of evidence suggests tumor-supporting roles of several members of the kallikrein-related peptidase (KLK) family, including KL …
Epigenetic regulation of KLK7 gene expression in pancreatic and cervical cancer cells.
Raju I, Kaushal GP, Haun RS. Raju I, et al. Biol Chem. 2016 Nov 1;397(11):1135-1146. doi: 10.1515/hsz-2015-0307. Biol Chem. 2016. PMID: 27279059
Examination of KLK7 mRNA levels in pancreatic cancer cell lines revealed that it is readily detected in MIA PaCa-2 and PK-1 cells, but not in Panc-1 cells. Treatment of Panc-1 cells with the histone deacetylase (HDAC) inhibitor trichostatin A (TSA) significantly ind …
Examination of KLK7 mRNA levels in pancreatic cancer cell lines revealed that it is readily detected in MIA PaCa-2 and PK-1 ce …
Integration of Two In-depth Quantitative Proteomics Approaches Determines the Kallikrein-related Peptidase 7 (KLK7) Degradome in Ovarian Cancer Cell Secretome.
Silva LM, Kryza T, Stoll T, Hoogland C, Dong Y, Stephens CR, Hastie ML, Magdolen V, Kleifeld O, Gorman JJ, Clements JA. Silva LM, et al. Mol Cell Proteomics. 2019 May;18(5):818-836. doi: 10.1074/mcp.RA118.001304. Epub 2019 Jan 31. Mol Cell Proteomics. 2019. PMID: 30705123 Free PMC article.
Kallikrein-related peptidase 7 (KLK7) is a serine peptidase that is over expressed in ovarian cancer. In vitro functional analyses have suggested KLK7 to play a cancer progressive role, although monitoring of KLK7 expression has suggested a cont …
Kallikrein-related peptidase 7 (KLK7) is a serine peptidase that is over expressed in ovarian cancer. In vitro functional anal …
The Role of Kallikrein 7 in Tumorigenesis.
Xiang F, Wang Y, Cao C, Li Q, Deng H, Zheng J, Liu X, Tan X. Xiang F, et al. Curr Med Chem. 2022;29(15):2617-2631. doi: 10.2174/0929867328666210915104537. Curr Med Chem. 2022. PMID: 34525904 Review.
Abnormally high expression of KLK7 is closely related to the occurrence and development of various types of cancer. Therefore, KLK7 has been identified as a potential target for cancer drug development design in recent years. ...
Abnormally high expression of KLK7 is closely related to the occurrence and development of various types of cancer. Therefore, …
[The expression of KLK7 in pancreatic cancer and the effects on the biological behavior of pancreatic cancer cells].
Zheng SL, Feng MY, Yang G, Xiong GB, Zheng LF, Zhang TP, Zhao YP. Zheng SL, et al. Zhonghua Wai Ke Za Zhi. 2018 May 1;56(5):391-397. doi: 10.3760/cma.j.issn.0529-5815.2018.05.013. Zhonghua Wai Ke Za Zhi. 2018. PMID: 29779317 Chinese.
Objective: To investigate the expression of KLK7 in pancreatic cancer and its clinical significance. Methods: Immunohistochemistry was used to detect the expression of KLK7 protein in pancreatic cancer tissue microarray with 92 samples. ...Results: The …
Objective: To investigate the expression of KLK7 in pancreatic cancer and its clinical significance. Methods: Immunohistochemi …
Clinical value of protein expression of kallikrein-related peptidase 7 (KLK7) in ovarian cancer.
Dorn J, Gkazepis A, Kotzsch M, Kremer M, Propping C, Mayer K, Mengele K, Diamandis EP, Kiechle M, Magdolen V, Schmitt M. Dorn J, et al. Biol Chem. 2014 Jan;395(1):95-107. doi: 10.1515/hsz-2013-0172. Biol Chem. 2014. PMID: 23999494
Expression of the kallikrein-related peptidase 7 (KLK7) is dysregulated in ovarian cancer. We assessed KLK7 expression by ELISA and quantitative immunohistochemistry and analyzed its association with clinicopathological parameters and patients' outcome. KL …
Expression of the kallikrein-related peptidase 7 (KLK7) is dysregulated in ovarian cancer. We assessed KLK7 expression …
High levels of KLK7 protein expression are related to a favorable prognosis in triple-negative breast cancer patients.
Geng X, Babayeva L, Walch A, Aubele M, Groß E, Kiechle M, Bronger H, Dreyer T, Magdolen V, Dorn J. Geng X, et al. Am J Cancer Res. 2020 Jun 1;10(6):1785-1792. eCollection 2020. Am J Cancer Res. 2020. PMID: 32642290 Free PMC article.
However, there are contradictory reports in breast cancer whether KLK7 represents an unfavorable or favorable prognostic biomarker. ...These results strongly indicate that KLK7 is a favorable prognostic biomarker in triple-negative breast cancer....
However, there are contradictory reports in breast cancer whether KLK7 represents an unfavorable or favorable prognostic bioma …
KLK7, KLK10, and KLK11 in Papillary Thyroid Cancer: Bioinformatic Analysis and Experimental Validation.
Ni T, Zhao RH, Wu JF, Li CY, Xue G, Lin X. Ni T, et al. Biochem Genet. 2024 Feb 5. doi: 10.1007/s10528-024-10679-8. Online ahead of print. Biochem Genet. 2024. PMID: 38316654
Survival analysis demonstrated that KLK4/5/7/9-12/14 was associated with overall survival in patients with thyroid cancer. Not only were KLK genes strongly associated with cancer-related pathways, but also KLK7/10/11 was associated with immune-cell infiltrati …
Survival analysis demonstrated that KLK4/5/7/9-12/14 was associated with overall survival in patients with thyroid cancer. Not only w …
Clinical significance of kallikrein-related peptidase 7 (KLK7) in colorectal cancer.
Talieri M, Mathioudaki K, Prezas P, Alexopoulou DK, Diamandis EP, Xynopoulos D, Ardavanis A, Arnogiannaki N, Scorilas A. Talieri M, et al. Thromb Haemost. 2009 Apr;101(4):741-7. Thromb Haemost. 2009. PMID: 19350120
A defined number of colon cancer samples were also examined by immunohistochemistry. KLK7 expression was higher in cancerous than in normal tissues. ...Present data suggest that KLK7 gene is up-regulated in colon cancer and its expression predic …
A defined number of colon cancer samples were also examined by immunohistochemistry. KLK7 expression was higher in cancerou …
123 results