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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 1
1993 1
1999 1
2002 2
2004 2
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2006 12
2007 4
2008 7
2009 9
2010 7
2011 10
2012 7
2013 9
2014 9
2015 12
2016 9
2017 16
2018 15
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2020 25
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2022 19
2023 25
2024 17

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219 results

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Page 1
KRT6A expedites bladder cancer progression, regulated by miR-31-5p.
Chen Y, Ji S, Ying J, Sun Y, Liu J, Yin G. Chen Y, et al. Cell Cycle. 2022 Jul;21(14):1479-1490. doi: 10.1080/15384101.2022.2054095. Epub 2022 Mar 20. Cell Cycle. 2022. PMID: 35311447 Free PMC article.
Accordingly, we performed a series of experiments to further verify the role of KRT6A in bladder tumor progression. Our results revealed that KRT6A promoted bladder tumor cell viability, proliferation, and adhesion, while diminishing bladder tumor cell apoptosis. .. …
Accordingly, we performed a series of experiments to further verify the role of KRT6A in bladder tumor progression. Our results revea …
KRT6A Promotes Lung Cancer Cell Growth and Invasion Through MYC-Regulated Pentose Phosphate Pathway.
Che D, Wang M, Sun J, Li B, Xu T, Lu Y, Pan H, Lu Z, Gu X. Che D, et al. Front Cell Dev Biol. 2021 Jun 21;9:694071. doi: 10.3389/fcell.2021.694071. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34235156 Free PMC article.
Although KRT6A upregulation in non-small cell lung cancer (NSCLC) has been reported, the regulatory mechanism and functional role of KRT6A in NSCLC development have been less well investigated. ...In addition, we discovered that lysine-specific demethylase 1A (LSD1) …
Although KRT6A upregulation in non-small cell lung cancer (NSCLC) has been reported, the regulatory mechanism and functional role of …
KRT6A Inhibits IL-1beta-Mediated Pyroptosis of Keratinocytes via Blocking IL-17 Signaling.
Li Y, Wu Q. Li Y, et al. Crit Rev Eukaryot Gene Expr. 2024;34(4):1-11. doi: 10.1615/CritRevEukaryotGeneExpr.2023050039. Crit Rev Eukaryot Gene Expr. 2024. PMID: 38505868
Overexpressed KRT6A suppressed inflammatory response, while KRT6A knockdown exerted the opposite effects. ...This KRT6A/IL-17 may be a novel target for AD....
Overexpressed KRT6A suppressed inflammatory response, while KRT6A knockdown exerted the opposite effects. ...This KRT6A …
Sinapine thiocyanate exhibited anti-colorectal cancer effects by inhibiting KRT6A/S100A2 axis.
Yang Y, Zeng Z, Li L, Lei S, Wu Y, Chen T, Zhang J. Yang Y, et al. Cancer Biol Ther. 2023 Dec 31;24(1):2249170. doi: 10.1080/15384047.2023.2249170. Cancer Biol Ther. 2023. PMID: 37647260 Free PMC article.
Low expression of KRT6A and S100A2 signatures indicated a favorable prognosis in CRC patients. Moreover, we found overexpression of KRT6A relieved the inhibitory effects of ST in CRC cells. Furthermore, ST inhibited the CRC cell proliferation in vivo, and reduced …
Low expression of KRT6A and S100A2 signatures indicated a favorable prognosis in CRC patients. Moreover, we found overexpression of …
Pachyonychia Congenita: A Spectrum of KRT6a Mutations in Australian Patients.
Forrest CE, Casey G, Mordaunt DA, Thompson EM, Gordon L. Forrest CE, et al. Pediatr Dermatol. 2016 May;33(3):337-42. doi: 10.1111/pde.12841. Epub 2016 Apr 4. Pediatr Dermatol. 2016. PMID: 27041546 Review.
It is associated with mutations in five differentiation-specific keratin genes, KRT6A, KRT6B, KRT6C, KRT16, or KRT17. OBJECTIVES: Living with Pachyonychia Congenita can be isolating. ...In collaboration with the International Pachyonychia Congenita Research Registry (IPCRR …
It is associated with mutations in five differentiation-specific keratin genes, KRT6A, KRT6B, KRT6C, KRT16, or KRT17. OBJECTIVES: Liv …
Identification of SRXN1 and KRT6A as Key Genes in Smoking-Related Non-Small-Cell Lung Cancer Through Bioinformatics and Functional Analyses.
Zhou J, Jiang G, Xu E, Zhou J, Liu L, Yang Q. Zhou J, et al. Front Oncol. 2022 Jan 5;11:810301. doi: 10.3389/fonc.2021.810301. eCollection 2021. Front Oncol. 2022. PMID: 35071014 Free PMC article.
A survival analysis revealed three genes with potential prognostic value, namely SRXN1, KRT6A and JAKMIP3. A univariate Cox analysis revealed significant associations of elevated SRXN1 and KRT6A expression with prognosis. ...Furthermore, inhibition of SRXN1 or KR …
A survival analysis revealed three genes with potential prognostic value, namely SRXN1, KRT6A and JAKMIP3. A univariate Cox analysis …
Single-cell transcriptomics combined with interstitial fluid proteomics defines cell type-specific immune regulation in atopic dermatitis.
Rojahn TB, Vorstandlechner V, Krausgruber T, Bauer WM, Alkon N, Bangert C, Thaler FM, Sadeghyar F, Fortelny N, Gernedl V, Rindler K, Elbe-Bürger A, Bock C, Mildner M, Brunner PM. Rojahn TB, et al. J Allergy Clin Immunol. 2020 Nov;146(5):1056-1069. doi: 10.1016/j.jaci.2020.03.041. Epub 2020 Apr 25. J Allergy Clin Immunol. 2020. PMID: 32344053
Using single-cell RNA sequencing, we found comparable transcriptional profiles of key inflammatory pathways between blister and biopsy AD, but suction blistering was superior in cell-specific resolution for high-abundance transcripts (KRT1/KRT10, KRT16/KRT6A, S100A8/S100A9 …
Using single-cell RNA sequencing, we found comparable transcriptional profiles of key inflammatory pathways between blister and biopsy AD, b …
Sunitinib decreases the expression of KRT6A and SERPINB1 in 3D human epidermal models.
Yoshida A, Yamamoto K, Ishida T, Omura T, Itoh T, Nishigori C, Sakane T, Yano I. Yoshida A, et al. Exp Dermatol. 2021 Mar;30(3):337-346. doi: 10.1111/exd.14230. Epub 2020 Nov 17. Exp Dermatol. 2021. PMID: 33135264
Inhibitors of the ERK and p38 MAPK signal pathways also significantly decreased KRT6A expression. Sunitinib-induced decrease in KRT6A expression was suppressed by the inhibition of glycogen synthase kinase-3beta by enhancing ERK1/2 and p38 MAPK phosphorylation. Thus …
Inhibitors of the ERK and p38 MAPK signal pathways also significantly decreased KRT6A expression. Sunitinib-induced decrease in KR …
Pachyonychia Congenita.
Smith FJD, Hansen CD, Hull PR, Kaspar RL, McLean WHI, O’Toole E, Sprecher E. Smith FJD, et al. 2006 Jan 27 [updated 2017 Nov 30]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 2006 Jan 27 [updated 2017 Nov 30]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 20301457 Free Books & Documents. Review.
DIAGNOSIS/TESTING: PC is diagnosed by clinical findings and/or by the identification of a heterozygous pathogenic variant in one of the five keratin genes known to cause PC: KRT6A, KRT6B, KRT6C, KRT16, and KRT17. MANAGEMENT: Treatment of manifestations: Pain from the palmo …
DIAGNOSIS/TESTING: PC is diagnosed by clinical findings and/or by the identification of a heterozygous pathogenic variant in one of the five …
219 results