Kadia TM - Search Results

1

TP53 mutations in newly diagnosed acute myeloid leukemia: Clinicomolecular characteristics, response to therapy, and outcomes.

Kadia TM, Jain P, Ravandi F, Garcia-Manero G, Andreef M, Takahashi K, Borthakur G, Jabbour E, Konopleva M, Daver NG, Dinardo C, Pierce S, Kanagal-Shamanna R, Patel K, Estrov Z, Cortes J, Kantarjian HM. Kadia TM, et al. Cancer. 2016 Nov 15;122(22):3484-3491. doi: 10.1002/cncr.30203. Epub 2016 Jul 26. Cancer. 2016. PMID: 27463065 Free PMC article.

2

Residual DNA methylation at remission is prognostic in adult Philadelphia chromosome-negative acute lymphocytic leukemia.

Yang H, Kadia T, Xiao L, Bueso-Ramos CE, Hoshino K, Thomas DA, O'Brien S, Jabbour E, Pierce S, Rosner GL, Kantarjian HM, Garcia-Manero G. Yang H, et al. Blood. 2009 Feb 26;113(9):1892-8. doi: 10.1182/blood-2008-02-141002. Epub 2008 Dec 23. Blood. 2009. PMID: 19109226 Free PMC article.

3

Nilotinib as front-line treatment for patients with chronic myeloid leukemia in early chronic phase.

Cortes JE, Jones D, O'Brien S, Jabbour E, Konopleva M, Ferrajoli A, Kadia T, Borthakur G, Stigliano D, Shan J, Kantarjian H. Cortes JE, et al. J Clin Oncol. 2010 Jan 20;28(3):392-7. doi: 10.1200/JCO.2009.25.4896. Epub 2009 Dec 14. J Clin Oncol. 2010. PMID: 20008621 Free PMC article.

4

A phase I study of vorinostat in combination with idarubicin in relapsed or refractory leukaemia.

Kadia TM, Yang H, Ferrajoli A, Maddipotti S, Schroeder C, Madden TL, Holleran JL, Egorin MJ, Ravandi F, Thomas DA, Newsome W, Sanchez-Gonzalez B, Zwiebel JA, Espinoza-Delgado I, Kantarjian HM, Garcia-Manero G. Kadia TM, et al. Br J Haematol. 2010 Jul;150(1):72-82. doi: 10.1111/j.1365-2141.2010.08211.x. Epub 2010 Apr 29. Br J Haematol. 2010. PMID: 20456355 Free PMC article. Clinical Trial.

5

The combination of a histone deacetylase inhibitor with the Bcl-2 homology domain-3 mimetic GX15-070 has synergistic antileukemia activity by activating both apoptosis and autophagy.

Wei Y, Kadia T, Tong W, Zhang M, Jia Y, Yang H, Hu Y, Tambaro FP, Viallet J, O'Brien S, Garcia-Manero G. Wei Y, et al. Clin Cancer Res. 2010 Aug 1;16(15):3923-32. doi: 10.1158/1078-0432.CCR-10-0032. Epub 2010 Jun 10. Clin Cancer Res. 2010. PMID: 20538760 Free PMC article.

6

Intensive chemotherapy does not benefit most older patients (age 70 years or older) with acute myeloid leukemia.

Kantarjian H, Ravandi F, O'Brien S, Cortes J, Faderl S, Garcia-Manero G, Jabbour E, Wierda W, Kadia T, Pierce S, Shan J, Keating M, Freireich EJ. Kantarjian H, et al. Blood. 2010 Nov 25;116(22):4422-9. doi: 10.1182/blood-2010-03-276485. Epub 2010 Jul 28. Blood. 2010. PMID: 20668231 Free PMC article.

7

Peripheral blasts on day 21 of induction chemotherapy in a patient with core binding factor acute myeloid leukemia: more than meets the eye.

Parikh SA, Kadia T, Jabbour E. Parikh SA, et al. Clin Lymphoma Myeloma Leuk. 2010 Aug;10(4):301-2. doi: 10.3816/CLML.2010.n.062. Clin Lymphoma Myeloma Leuk. 2010. PMID: 20709669

8

The combination of a histone deacetylase inhibitor with the BH3-mimetic GX15-070 has synergistic antileukemia activity by activating both apoptosis and autophagy.

Wei Y, Kadia T, Tong W, Zhang M, Jia Y, Yang H, Hu Y, Viallet J, O'Brien S, Garcia-Manero G. Wei Y, et al. Autophagy. 2010 Oct;6(7):976-8. doi: 10.4161/auto.6.7.13117. Epub 2010 Oct 23. Autophagy. 2010. PMID: 20729640

9

Role of epigenetic therapy in myelodysplastic syndrome.

Kadia TM, Garcia-Manero G. Kadia TM, et al. Expert Rev Hematol. 2008 Dec;1(2):161-74. doi: 10.1586/17474086.1.2.161. Expert Rev Hematol. 2008. PMID: 21082921 Free PMC article. Review.

10

Phase I/II multicenter study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of AZD4877 in patients with refractory acute myeloid leukemia.

Kantarjian HM, Padmanabhan S, Stock W, Tallman MS, Curt GA, Li J, Osmukhina A, Wu K, Huszar D, Borthukar G, Faderl S, Garcia-Manero G, Kadia T, Sankhala K, Odenike O, Altman JK, Minden M. Kantarjian HM, et al. Invest New Drugs. 2012 Jun;30(3):1107-15. doi: 10.1007/s10637-011-9660-2. Epub 2011 Apr 15. Invest New Drugs. 2012. PMID: 21494838 Free PMC article. Clinical Trial.

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