Kaldis P - Search Results

1

Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration.

Diril MK, Ratnacaram CK, Padmakumar VC, Du T, Wasser M, Coppola V, Tessarollo L, Kaldis P. Diril MK, et al. Among authors: kaldis p. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3826-31. doi: 10.1073/pnas.1115201109. Epub 2012 Feb 21. Proc Natl Acad Sci U S A. 2012. PMID: 22355113 Free PMC article.

2

Transforming growth factor beta targeted inactivation of cyclin E:cyclin-dependent kinase 2 (Cdk2) complexes by inhibition of Cdk2 activating kinase activity.

Nagahara H, Ezhevsky SA, Vocero-Akbani AM, Kaldis P, Solomon MJ, Dowdy SF. Nagahara H, et al. Among authors: kaldis p. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14961-6. doi: 10.1073/pnas.96.26.14961. Proc Natl Acad Sci U S A. 1999. PMID: 10611320 Free PMC article.

3

Cdk2 knockout mice are viable.

Berthet C, Aleem E, Coppola V, Tessarollo L, Kaldis P. Berthet C, et al. Among authors: kaldis p. Curr Biol. 2003 Oct 14;13(20):1775-85. doi: 10.1016/j.cub.2003.09.024. Curr Biol. 2003. PMID: 14561402 Free article.

4

Genetic substitution of Cdk1 by Cdk2 leads to embryonic lethality and loss of meiotic function of Cdk2.

Satyanarayana A, Berthet C, Lopez-Molina J, Coppola V, Tessarollo L, Kaldis P. Satyanarayana A, et al. Among authors: kaldis p. Development. 2008 Oct;135(20):3389-400. doi: 10.1242/dev.024919. Epub 2008 Sep 11. Development. 2008. PMID: 18787066 Free PMC article.

5

Cdk2 and Cdk4 activities are dispensable for tumorigenesis caused by the loss of p53.

Padmakumar VC, Aleem E, Berthet C, Hilton MB, Kaldis P. Padmakumar VC, et al. Among authors: kaldis p. Mol Cell Biol. 2009 May;29(10):2582-93. doi: 10.1128/MCB.00952-08. Epub 2009 Mar 23. Mol Cell Biol. 2009. PMID: 19307310 Free PMC article.

6

Established and novel Cdk/cyclin complexes regulating the cell cycle and development.

Gopinathan L, Ratnacaram CK, Kaldis P. Gopinathan L, et al. Among authors: kaldis p. Results Probl Cell Differ. 2011;53:365-89. doi: 10.1007/978-3-642-19065-0_16. Results Probl Cell Differ. 2011. PMID: 21630153 Review.

7

Cdk1, but not Cdk2, is the sole Cdk that is essential and sufficient to drive resumption of meiosis in mouse oocytes.

Adhikari D, Zheng W, Shen Y, Gorre N, Ning Y, Halet G, Kaldis P, Liu K. Adhikari D, et al. Among authors: kaldis p. Hum Mol Genet. 2012 Jun 1;21(11):2476-84. doi: 10.1093/hmg/dds061. Epub 2012 Feb 24. Hum Mol Genet. 2012. PMID: 22367880

8

IFN-gamma AU-rich element removal promotes chronic IFN-gamma expression and autoimmunity in mice.

Hodge DL, Berthet C, Coppola V, Kastenmüller W, Buschman MD, Schaughency PM, Shirota H, Scarzello AJ, Subleski JJ, Anver MR, Ortaldo JR, Lin F, Reynolds DA, Sanford ME, Kaldis P, Tessarollo L, Klinman DM, Young HA. Hodge DL, et al. Among authors: kaldis p. J Autoimmun. 2014 Sep;53:33-45. doi: 10.1016/j.jaut.2014.02.003. Epub 2014 Feb 28. J Autoimmun. 2014. PMID: 24583068 Free PMC article.

9

Identification of transcriptional and metabolic programs related to mammalian cell size.

Miettinen TP, Pessa HK, Caldez MJ, Fuhrer T, Diril MK, Sauer U, Kaldis P, Björklund M. Miettinen TP, et al. Among authors: kaldis p. Curr Biol. 2014 Mar 17;24(6):598-608. doi: 10.1016/j.cub.2014.01.071. Epub 2014 Mar 6. Curr Biol. 2014. PMID: 24613310 Free PMC article.

10

Loss of Cdk2 and cyclin A2 impairs cell proliferation and tumorigenesis.

Gopinathan L, Tan SL, Padmakumar VC, Coppola V, Tessarollo L, Kaldis P. Gopinathan L, et al. Among authors: kaldis p. Cancer Res. 2014 Jul 15;74(14):3870-9. doi: 10.1158/0008-5472.CAN-13-3440. Epub 2014 May 6. Cancer Res. 2014. PMID: 24802190 Free PMC article.

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