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Alternative splicing of Apoptosis Stimulating Protein of TP53-2 (ASPP2) results in an oncogenic isoform promoting migration and therapy resistance in soft tissue sarcoma (STS).
Tsintari V, Walter B, Fend F, Overkamp M, Rothermundt C, Lopez CD, Schittenhelm MM, Kampa-Schittenhelm KM. Tsintari V, et al. Among authors: kampa schittenhelm km. BMC Cancer. 2022 Jul 2;22(1):725. doi: 10.1186/s12885-022-09726-7. BMC Cancer. 2022. PMID: 35780096 Free PMC article.
Alternative splicing of the tumor suppressor ASPP2 results in a stress-inducible, oncogenic isoform prevalent in acute leukemia.
Schittenhelm MM, Walter B, Tsintari V, Federmann B, Bajrami Saipi M, Akmut F, Illing B, Mau-Holzmann U, Fend F, Lopez CD, Kampa-Schittenhelm KM. Schittenhelm MM, et al. Among authors: kampa schittenhelm km. EBioMedicine. 2019 Apr;42:340-351. doi: 10.1016/j.ebiom.2019.03.028. Epub 2019 Apr 2. EBioMedicine. 2019. PMID: 30952616 Free PMC article.
Mutant TP53 driving the Warburg Effect in Mantle Cell lymphoma.
Kliebhan J, Besse A, Kampa-Schittenhelm K, Schittenhelm M, Driessen C. Kliebhan J, et al. Clin Case Rep. 2022 Oct 3;10(10):e6296. doi: 10.1002/ccr3.6296. eCollection 2022 Oct. Clin Case Rep. 2022. PMID: 36225622 Free PMC article.
Epigenetic activation of O-linked β-N-acetylglucosamine transferase overrides the differentiation blockage in acute leukemia.
Kampa-Schittenhelm KM, Haverkamp T, Bonin M, Tsintari V, Bühring HJ, Haeusser L, Blumenstock G, Dreher ST, Ganief T, Akmut F, Illing B, Mau-Holzmann UA, Bonzheim I, Schleicher E, Vogel W, Schittenhelm MM. Kampa-Schittenhelm KM, et al. EBioMedicine. 2020 Apr;54:102678. doi: 10.1016/j.ebiom.2020.102678. Epub 2020 Apr 6. EBioMedicine. 2020. PMID: 32272438 Free PMC article.
14 results