Kampmann M - Search Results

1

CRISPR-based screens uncover determinants of immunotherapy response in multiple myeloma.

Ramkumar P, Abarientos AB, Tian R, Seyler M, Leong JT, Chen M, Choudhry P, Hechler T, Shah N, Wong SW, Martin TG, Wolf JL, Roybal KT, Pahl A, Taunton J, Wiita AP, Kampmann M. Ramkumar P, et al. Among authors: kampmann m. Blood Adv. 2020 Jul 14;4(13):2899-2911. doi: 10.1182/bloodadvances.2019001346. Blood Adv. 2020. PMID: 32589729 Free PMC article.

2

Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia.

Kruth KA, Fang M, Shelton DN, Abu-Halawa O, Mahling R, Yang H, Weissman JS, Loh ML, Müschen M, Tasian SK, Bassik MC, Kampmann M, Pufall MA. Kruth KA, et al. Among authors: kampmann m. Blood. 2017 Jun 1;129(22):3000-3008. doi: 10.1182/blood-2017-02-766204. Epub 2017 Apr 19. Blood. 2017. PMID: 28424165 Free PMC article.

3

Elucidating drug targets and mechanisms of action by genetic screens in mammalian cells.

Kampmann M. Kampmann M. Chem Commun (Camb). 2017 Jun 29;53(53):7162-7167. doi: 10.1039/c7cc02349a. Chem Commun (Camb). 2017. PMID: 28487920 Free PMC article. Review.

4

Dual gene activation and knockout screen reveals directional dependencies in genetic networks.

Boettcher M, Tian R, Blau JA, Markegard E, Wagner RT, Wu D, Mo X, Biton A, Zaitlen N, Fu H, McCormick F, Kampmann M, McManus MT. Boettcher M, et al. Among authors: kampmann m. Nat Biotechnol. 2018 Feb;36(2):170-178. doi: 10.1038/nbt.4062. Epub 2018 Jan 15. Nat Biotechnol. 2018. PMID: 29334369 Free PMC article.

5

Mapping the Genetic Landscape of Human Cells.

Horlbeck MA, Xu A, Wang M, Bennett NK, Park CY, Bogdanoff D, Adamson B, Chow ED, Kampmann M, Peterson TR, Nakamura K, Fischbach MA, Weissman JS, Gilbert LA. Horlbeck MA, et al. Among authors: kampmann m. Cell. 2018 Aug 9;174(4):953-967.e22. doi: 10.1016/j.cell.2018.06.010. Epub 2018 Jul 19. Cell. 2018. PMID: 30033366 Free PMC article.

6

CRISPR-based genetic interaction maps inform therapeutic strategies in cancer.

Ramkumar P, Kampmann M. Ramkumar P, et al. Among authors: kampmann m. Transl Cancer Res. 2018 Feb;7(Suppl 1):S61-S67. doi: 10.21037/tcr.2018.01.02. Transl Cancer Res. 2018. PMID: 30148072 Free PMC article. No abstract available.

7

A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure.

Mendelsohn BA, Bennett NK, Darch MA, Yu K, Nguyen MK, Pucciarelli D, Nelson M, Horlbeck MA, Gilbert LA, Hyun W, Kampmann M, Nakamura JL, Nakamura K. Mendelsohn BA, et al. Among authors: kampmann m. PLoS Biol. 2018 Aug 27;16(8):e2004624. doi: 10.1371/journal.pbio.2004624. eCollection 2018 Aug. PLoS Biol. 2018. PMID: 30148842 Free PMC article.

8

Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether.

Torres SE, Gallagher CM, Plate L, Gupta M, Liem CR, Guo X, Tian R, Stroud RM, Kampmann M, Weissman JS, Walter P. Torres SE, et al. Among authors: kampmann m. Elife. 2019 May 31;8:e46595. doi: 10.7554/eLife.46595. Elife. 2019. PMID: 31149896 Free PMC article.

9

CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons.

Tian R, Gachechiladze MA, Ludwig CH, Laurie MT, Hong JY, Nathaniel D, Prabhu AV, Fernandopulle MS, Patel R, Abshari M, Ward ME, Kampmann M. Tian R, et al. Among authors: kampmann m. Neuron. 2019 Oct 23;104(2):239-255.e12. doi: 10.1016/j.neuron.2019.07.014. Epub 2019 Aug 15. Neuron. 2019. PMID: 31422865 Free PMC article.

10

Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation.

Chen JJ, Nathaniel DL, Raghavan P, Nelson M, Tian R, Tse E, Hong JY, See SK, Mok SA, Hein MY, Southworth DR, Grinberg LT, Gestwicki JE, Leonetti MD, Kampmann M. Chen JJ, et al. Among authors: kampmann m. J Biol Chem. 2019 Dec 13;294(50):18952-18966. doi: 10.1074/jbc.RA119.009432. Epub 2019 Oct 2. J Biol Chem. 2019. PMID: 31578281 Free PMC article.

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