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Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells.
Yamaguchi K, Chen X, Rodgers B, Miura F, Bashtrykov P, Bonhomme F, Salinas-Luypaert C, Haxholli D, Gutekunst N, Aygenli BÖ, Ferry L, Kirsh O, Laisné M, Scelfo A, Ugur E, Arimondo PB, Leonhardt H, Kanemaki MT, Bartke T, Fachinetti D, Jeltsch A, Ito T, Defossez PA. Yamaguchi K, et al. Among authors: kanemaki mt. Nat Commun. 2024 Apr 5;15(1):2960. doi: 10.1038/s41467-024-47314-4. Nat Commun. 2024. PMID: 38580649 Free PMC article.
Exosomes maintain cellular homeostasis by excreting harmful DNA from cells.
Takahashi A, Okada R, Nagao K, Kawamata Y, Hanyu A, Yoshimoto S, Takasugi M, Watanabe S, Kanemaki MT, Obuse C, Hara E. Takahashi A, et al. Among authors: kanemaki mt. Nat Commun. 2017 May 16;8:15287. doi: 10.1038/ncomms15287. Nat Commun. 2017. PMID: 28508895 Free PMC article.
High-throughput Oligopaint screen identifies druggable 3D genome regulators.
Park DS, Nguyen SC, Isenhart R, Shah PP, Kim W, Barnett RJ, Chandra A, Luppino JM, Harke J, Wai M, Walsh PJ, Abdill RJ, Yang R, Lan Y, Yoon S, Yunker R, Kanemaki MT, Vahedi G, Phillips-Cremins JE, Jain R, Joyce EF. Park DS, et al. Among authors: kanemaki mt. Nature. 2023 Aug;620(7972):209-217. doi: 10.1038/s41586-023-06340-w. Epub 2023 Jul 12. Nature. 2023. PMID: 37438531
Global landscape of replicative DNA polymerase usage in the human genome.
Koyanagi E, Kakimoto Y, Minamisawa T, Yoshifuji F, Natsume T, Higashitani A, Ogi T, Carr AM, Kanemaki MT, Daigaku Y. Koyanagi E, et al. Among authors: kanemaki mt. Nat Commun. 2022 Nov 24;13(1):7221. doi: 10.1038/s41467-022-34929-8. Nat Commun. 2022. PMID: 36434012 Free PMC article.
RNaseH2A downregulation drives inflammatory gene expression via genomic DNA fragmentation in senescent and cancer cells.
Sugawara S, Okada R, Loo TM, Tanaka H, Miyata K, Chiba M, Kawasaki H, Katoh K, Kaji S, Maezawa Y, Yokote K, Nakayama M, Oshima M, Nagao K, Obuse C, Nagayama S, Takubo K, Nakanishi A, Kanemaki MT, Hara E, Takahashi A. Sugawara S, et al. Among authors: kanemaki mt. Commun Biol. 2022 Dec 28;5(1):1420. doi: 10.1038/s42003-022-04369-7. Commun Biol. 2022. PMID: 36577784 Free PMC article.
83 results