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WT1 targets Gas1 to maintain nephron progenitor cells by modulating FGF signals.
Kann M, Bae E, Lenz MO, Li L, Trannguyen B, Schumacher VA, Taglienti ME, Bordeianou L, Hartwig S, Rinschen MM, Schermer B, Benzing T, Fan CM, Kreidberg JA. Kann M, et al. Development. 2015 Apr 1;142(7):1254-66. doi: 10.1242/dev.119735. Development. 2015. PMID: 25804736 Free PMC article.
N-Degradomic Analysis Reveals a Proteolytic Network Processing the Podocyte Cytoskeleton.
Rinschen MM, Hoppe AK, Grahammer F, Kann M, Völker LA, Schurek EM, Binz J, Höhne M, Demir F, Malisic M, Huber TB, Kurschat C, Kizhakkedathu JN, Schermer B, Huesgen PF, Benzing T. Rinschen MM, et al. Among authors: kann m. J Am Soc Nephrol. 2017 Oct;28(10):2867-2878. doi: 10.1681/ASN.2016101119. Epub 2017 Jul 19. J Am Soc Nephrol. 2017. PMID: 28724775 Free PMC article.
Single-nephron proteomes connect morphology and function in proteinuric kidney disease.
Höhne M, Frese CK, Grahammer F, Dafinger C, Ciarimboli G, Butt L, Binz J, Hackl MJ, Rahmatollahi M, Kann M, Schneider S, Altintas MM, Schermer B, Reinheckel T, Göbel H, Reiser J, Huber TB, Kramann R, Seeger-Nukpezah T, Liebau MC, Beck BB, Benzing T, Beyer A, Rinschen MM. Höhne M, et al. Among authors: kann m. Kidney Int. 2018 Jun;93(6):1308-1319. doi: 10.1016/j.kint.2017.12.012. Epub 2018 Mar 9. Kidney Int. 2018. PMID: 29530281 Free article.
Protein half-life determines expression of proteostatic networks in podocyte differentiation.
Schroeter CB, Koehler S, Kann M, Schermer B, Benzing T, Brinkkoetter PT, Rinschen MM. Schroeter CB, et al. Among authors: kann m. FASEB J. 2018 Sep;32(9):4696-4713. doi: 10.1096/fj.201701307R. Epub 2018 Apr 25. FASEB J. 2018. PMID: 29694247
These data suggest that regulation of protein turnover of particular cellular functions determines podocyte differentiation, a paradigm involving mitophagy and, potentially, of importance in conditions of increased podocyte stress and damage.-Schroeter, C. B., Koehler, S., Kan …
These data suggest that regulation of protein turnover of particular cellular functions determines podocyte differentiation, a paradigm invo …
A Single-Cell Transcriptome Atlas of the Mouse Glomerulus.
Karaiskos N, Rahmatollahi M, Boltengagen A, Liu H, Hoehne M, Rinschen M, Schermer B, Benzing T, Rajewsky N, Kocks C, Kann M, Müller RU. Karaiskos N, et al. Among authors: kann m. J Am Soc Nephrol. 2018 Aug;29(8):2060-2068. doi: 10.1681/ASN.2018030238. Epub 2018 May 24. J Am Soc Nephrol. 2018. PMID: 29794128 Free PMC article.
Constitutive activation of the mTOR signaling pathway within the normal glomerulus.
McMahon GM, Datta D, Bruneau S, Kann M, Khalid M, Ho J, Seto T, Kreidberg JA, Stillman IE, Briscoe DM. McMahon GM, et al. Among authors: kann m. Biochem Biophys Res Commun. 2012 Aug 24;425(2):244-9. doi: 10.1016/j.bbrc.2012.07.075. Epub 2012 Jul 22. Biochem Biophys Res Commun. 2012. PMID: 22828505 Free PMC article.
YAP-mediated mechanotransduction determines the podocyte's response to damage.
Rinschen MM, Grahammer F, Hoppe AK, Kohli P, Hagmann H, Kretz O, Bertsch S, Höhne M, Göbel H, Bartram MP, Gandhirajan RK, Krüger M, Brinkkoetter PT, Huber TB, Kann M, Wickström SA, Benzing T, Schermer B. Rinschen MM, et al. Among authors: kann m. Sci Signal. 2017 Apr 11;10(474):eaaf8165. doi: 10.1126/scisignal.aaf8165. Sci Signal. 2017. PMID: 28400537
211 results