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Peptide conjugation of 2'-O-methyl phosphorothioate antisense oligonucleotides enhances cardiac uptake and exon skipping in mdx mice.
Nucleic Acid Ther. 2014 Feb;24(1):25-36. doi: 10.1089/nat.2013.0448. Epub 2013 Dec 9.
Nucleic Acid Ther. 2014.
PMID: 24320790
Prednisolone treatment does not interfere with 2'-O-methyl phosphorothioate antisense-mediated exon skipping in Duchenne muscular dystrophy.
Verhaart IE, Heemskerk H, Karnaoukh TG, Kolfschoten IG, Vroon A, van Ommen GJ, van Deutekom JC, Aartsma-Rus A.
Verhaart IE, et al. Among authors: karnaoukh tg.
Hum Gene Ther. 2012 Mar;23(3):262-73. doi: 10.1089/hum.2011.127. Epub 2012 Jan 26.
Hum Gene Ther. 2012.
PMID: 22017442
Free PMC article.
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Long-term Exon Skipping Studies With 2'-O-Methyl Phosphorothioate Antisense Oligonucleotides in Dystrophic Mouse Models.
Tanganyika-de Winter CL, Heemskerk H, Karnaoukh TG, van Putten M, de Kimpe SJ, van Deutekom J, Aartsma-Rus A.
Tanganyika-de Winter CL, et al. Among authors: karnaoukh tg.
Mol Ther Nucleic Acids. 2012 Sep 4;1(9):e44. doi: 10.1038/mtna.2012.38.
Mol Ther Nucleic Acids. 2012.
PMID: 23344236
Free PMC article.
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Dose-dependent pharmacokinetic profiles of 2'-O-methyl phosphorothioate antisense oligonucleotidesin mdx mice.
Verhaart IE, Tanganyika-de Winter CL, Karnaoukh TG, Kolfschoten IG, de Kimpe SJ, van Deutekom JC, Aartsma-Rus A.
Verhaart IE, et al. Among authors: karnaoukh tg.
Nucleic Acid Ther. 2013 Jun;23(3):228-37. doi: 10.1089/nat.2012.0398. Epub 2013 May 2.
Nucleic Acid Ther. 2013.
PMID: 23634945
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Preclinical studies on intestinal administration of antisense oligonucleotides as a model for oral delivery for treatment of duchenne muscular dystrophy.
van Putten M, Young C, van den Berg S, Pronk A, Hulsker M, Karnaoukh TG, Vermue R, van Dijk KW, de Kimpe S, Aartsma-Rus A.
van Putten M, et al. Among authors: karnaoukh tg.
Mol Ther Nucleic Acids. 2014 Nov 18;3(11):e211. doi: 10.1038/mtna.2014.62.
Mol Ther Nucleic Acids. 2014.
PMID: 25405468
Free PMC article.
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The licorice pentacyclic triterpenoid component 18β-glycyrrhetinic acid enhances the activity of antibiotics against strains of methicillin-resistant Staphylococcus aureus.
de Breij A, Karnaoukh TG, Schrumpf J, Hiemstra PS, Nibbering PH, van Dissel JT, de Visser PC.
de Breij A, et al. Among authors: karnaoukh tg.
Eur J Clin Microbiol Infect Dis. 2016 Apr;35(4):555-62. doi: 10.1007/s10096-015-2570-z. Epub 2016 Jan 15.
Eur J Clin Microbiol Infect Dis. 2016.
PMID: 26780691
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