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Peptide conjugation of 2'-O-methyl phosphorothioate antisense oligonucleotides enhances cardiac uptake and exon skipping in mdx mice.
Jirka SM, Heemskerk H, Tanganyika-de Winter CL, Muilwijk D, Pang KH, de Visser PC, Janson A, Karnaoukh TG, Vermue R, 't Hoen PA, van Deutekom JC, Aguilera B, Aartsma-Rus A. Jirka SM, et al. Among authors: karnaoukh tg. Nucleic Acid Ther. 2014 Feb;24(1):25-36. doi: 10.1089/nat.2013.0448. Epub 2013 Dec 9. Nucleic Acid Ther. 2014. PMID: 24320790
Preclinical studies on intestinal administration of antisense oligonucleotides as a model for oral delivery for treatment of duchenne muscular dystrophy.
van Putten M, Young C, van den Berg S, Pronk A, Hulsker M, Karnaoukh TG, Vermue R, van Dijk KW, de Kimpe S, Aartsma-Rus A. van Putten M, et al. Among authors: karnaoukh tg. Mol Ther Nucleic Acids. 2014 Nov 18;3(11):e211. doi: 10.1038/mtna.2014.62. Mol Ther Nucleic Acids. 2014. PMID: 25405468 Free PMC article.
The licorice pentacyclic triterpenoid component 18β-glycyrrhetinic acid enhances the activity of antibiotics against strains of methicillin-resistant Staphylococcus aureus.
de Breij A, Karnaoukh TG, Schrumpf J, Hiemstra PS, Nibbering PH, van Dissel JT, de Visser PC. de Breij A, et al. Among authors: karnaoukh tg. Eur J Clin Microbiol Infect Dis. 2016 Apr;35(4):555-62. doi: 10.1007/s10096-015-2570-z. Epub 2016 Jan 15. Eur J Clin Microbiol Infect Dis. 2016. PMID: 26780691