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Page 1
The Fate of Erythrocytes after Cerebral Hemorrhage.
Xia F, Keep RF, Ye F, Holste KG, Wan S, Xi G, Hua Y. Xia F, et al. Transl Stroke Res. 2022 Oct;13(5):655-664. doi: 10.1007/s12975-021-00980-8. Epub 2022 Jan 23. Transl Stroke Res. 2022. PMID: 35066815 Free PMC article. Review.
The aim of this review is to discuss the process of phagocytosis of erythrocytes by microglia or macrophages after cerebral hemorrhage, the effect of erythrolysis on brain injury, novel mechanisms of erythrocyte and phagocyte egress from the brain, and exciting new targets in thi …
The aim of this review is to discuss the process of phagocytosis of erythrocytes by microglia or macrophages after cerebral hemorrhage, the …
Chronic inflammation can transform the fate of normal and mutant hematopoietic stem cells.
Li J, Malouf C, Miles LA, Willis MB, Pietras EM, King KY. Li J, et al. Exp Hematol. 2023 Nov;127:8-13. doi: 10.1016/j.exphem.2023.08.008. Epub 2023 Aug 28. Exp Hematol. 2023. PMID: 37647982 Free article. Review.
Eric Pietras (University of Colorado Anschutz Medical Campus, United States) and Dr. Katherine Y. King (Baylor College of Medicine, United States) gave a presentation on this topic, which is summarized in this review article....
Eric Pietras (University of Colorado Anschutz Medical Campus, United States) and Dr. Katherine Y. King (Baylor College of Medicine, U …
Asymmetric Inheritance of Cell Fate Determinants: Focus on RNA.
Shlyakhtina Y, Moran KL, Portal MM. Shlyakhtina Y, et al. Noncoding RNA. 2019 May 9;5(2):38. doi: 10.3390/ncrna5020038. Noncoding RNA. 2019. PMID: 31075989 Free PMC article. Review.
Interestingly, whilst a handful of integral components of mammalian cells seem to follow a general pattern of asymmetric inheritance throughout division, the fate of RNA molecules largely remains a mystery. Herein, we will discuss current concepts of asymmetric inheritance …
Interestingly, whilst a handful of integral components of mammalian cells seem to follow a general pattern of asymmetric inheritance through …
Assessment of ecological hazards and environmental fate of disinfectant quaternary ammonium compounds.
DeLeo PC, Huynh C, Pattanayek M, Schmid KC, Pechacek N. DeLeo PC, et al. Ecotoxicol Environ Saf. 2020 Dec 15;206:111116. doi: 10.1016/j.ecoenv.2020.111116. Epub 2020 Sep 2. Ecotoxicol Environ Saf. 2020. PMID: 32890921 Free PMC article. Review.
Consequently, there is a robust database of information regarding the ecological hazards and environmental fate of ADBAC and DDAC; however, some of the data presented are from unpublished studies that have been submitted to and reviewed by regulatory agencies (i.e., EPA an …
Consequently, there is a robust database of information regarding the ecological hazards and environmental fate of ADBAC and DDAC; ho …
DNA methylation of genes in adipose tissue.
Pinnick KE, Karpe F. Pinnick KE, et al. Proc Nutr Soc. 2011 Feb;70(1):57-63. doi: 10.1017/S0029665110004015. Epub 2010 Dec 14. Proc Nutr Soc. 2011. PMID: 21144123 Review.
In this review, we will discuss the contribution of DNA methylation to the determination of cells of adipogenic fate as well as the role DNA methylation may play during adipocyte terminal differentiation....
In this review, we will discuss the contribution of DNA methylation to the determination of cells of adipogenic fate as well as the r …
The Role of Interferon-Gamma in Hematopoietic Stem Cell Development, Homeostasis, and Disease.
Morales-Mantilla DE, King KY. Morales-Mantilla DE, et al. Curr Stem Cell Rep. 2018;4(3):264-271. doi: 10.1007/s40778-018-0139-3. Epub 2018 Jul 23. Curr Stem Cell Rep. 2018. PMID: 30148048 Free PMC article. Review.
SUMMARY: Here, we explore the mechanisms by which IFN-gamma regulates HSC in both normal and pathological conditions. We focus on the role of IFN-gamma signaling in HSC fate decisions, and the transcriptional changes it elicits. Elucidating the mechanisms through which IFN …
SUMMARY: Here, we explore the mechanisms by which IFN-gamma regulates HSC in both normal and pathological conditions. We focus on the role o …
Adaptive Dosing of Nivolumab + Ipilimumab Immunotherapy Based Upon Early, Interim Radiographic Assessment in Advanced Melanoma (The ADAPT-IT Study).
Postow MA, Goldman DA, Shoushtari AN, Betof Warner A, Callahan MK, Momtaz P, Smithy JW, Naito E, Cugliari MK, Raber V, Eton O, Nair SG, Panageas KS, Wolchok JD, Chapman PB. Postow MA, et al. J Clin Oncol. 2022 Apr 1;40(10):1059-1067. doi: 10.1200/JCO.21.01570. Epub 2021 Dec 20. J Clin Oncol. 2022. PMID: 34928709 Free PMC article.
Patients without new lesions or index lesion tumor growth of > 4% had protocol-defined early favorable antitumor effect (FATE) and ceased nivo + ipi, transitioning to nivo monotherapy. Patients without FATE at week 6 received the standard third and fourth doses o …
Patients without new lesions or index lesion tumor growth of > 4% had protocol-defined early favorable antitumor effect (FATE) and …
Measuring Human Lipid Metabolism Using Deuterium Labeling: In Vivo and In Vitro Protocols.
Pinnick KE, Gunn PJ, Hodson L. Pinnick KE, et al. Methods Mol Biol. 2019;1862:83-96. doi: 10.1007/978-1-4939-8769-6_6. Methods Mol Biol. 2019. PMID: 30315461
Stable isotopes are powerful tools for tracing the metabolic fate of molecules in the human body. In this chapter, we focus on the use of deuterium ((2)H), a stable isotope of hydrogen, in the study of human lipid metabolism within the liver in vivo in humans and in vitro …
Stable isotopes are powerful tools for tracing the metabolic fate of molecules in the human body. In this chapter, we focus on the us …
Characterizing cesium sorption in freshwater settings using fluvial sediments and characteristic water chemistries.
Ratliff K, Mikelonis A, Duffy J. Ratliff K, et al. J Environ Manage. 2020 Jan 1;253:109688. doi: 10.1016/j.jenvman.2019.109688. Epub 2019 Oct 18. J Environ Manage. 2020. PMID: 31634742 Free PMC article.
Cesium-137 ((137)Cs) is a persistent contaminant that poses a significant risk to human health and the environment. Understanding the fate and transport of (137)Cs following a contamination incident is necessary for effective containment and remediation. ...
Cesium-137 ((137)Cs) is a persistent contaminant that poses a significant risk to human health and the environment. Understanding the fat
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