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Opportunities for Host-targeted Therapies for Malaria.
Glennon EKK, Dankwa S, Smith JD, Kaushansky A. Glennon EKK, et al. Among authors: kaushansky a. Trends Parasitol. 2018 Oct;34(10):843-860. doi: 10.1016/j.pt.2018.07.011. Epub 2018 Aug 16. Trends Parasitol. 2018. PMID: 30122551 Free PMC article. Review.
Identification of potent and selective N-myristoyltransferase inhibitors of Plasmodium vivax liver stage hypnozoites and schizonts.
Rodríguez-Hernández D, Vijayan K, Zigweid R, Fenwick MK, Sankaran B, Roobsoong W, Sattabongkot J, Glennon EKK, Myler PJ, Sunnerhagen P, Staker BL, Kaushansky A, Grøtli M. Rodríguez-Hernández D, et al. Among authors: kaushansky a. Nat Commun. 2023 Sep 5;14(1):5408. doi: 10.1038/s41467-023-41119-7. Nat Commun. 2023. PMID: 37669940 Free PMC article.
Complete Plasmodium falciparum liver-stage development in liver-chimeric mice.
Vaughan AM, Mikolajczak SA, Wilson EM, Grompe M, Kaushansky A, Camargo N, Bial J, Ploss A, Kappe SH. Vaughan AM, et al. Among authors: kaushansky a. J Clin Invest. 2012 Oct;122(10):3618-28. doi: 10.1172/JCI62684. Epub 2012 Sep 10. J Clin Invest. 2012. PMID: 22996664 Free PMC article.
Suppression of host p53 is critical for Plasmodium liver-stage infection.
Kaushansky A, Ye AS, Austin LS, Mikolajczak SA, Vaughan AM, Camargo N, Metzger PG, Douglass AN, MacBeath G, Kappe SH. Kaushansky A, et al. Cell Rep. 2013 Mar 28;3(3):630-7. doi: 10.1016/j.celrep.2013.02.010. Epub 2013 Mar 7. Cell Rep. 2013. PMID: 23478020 Free PMC article.
Host-based Prophylaxis Successfully Targets Liver Stage Malaria Parasites.
Douglass AN, Kain HS, Abdullahi M, Arang N, Austin LS, Mikolajczak SA, Billman ZP, Hume JCC, Murphy SC, Kappe SHI, Kaushansky A. Douglass AN, et al. Among authors: kaushansky a. Mol Ther. 2015 May;23(5):857-865. doi: 10.1038/mt.2015.18. Epub 2015 Feb 4. Mol Ther. 2015. PMID: 25648263 Free PMC article.
84 results