Kay TW - Search Results

1

Tumor necrosis factor alpha-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling.

Steinberg GR, Michell BJ, van Denderen BJ, Watt MJ, Carey AL, Fam BC, Andrikopoulos S, Proietto J, Görgün CZ, Carling D, Hotamisligil GS, Febbraio MA, Kay TW, Kemp BE. Steinberg GR, et al. Among authors: kay tw. Cell Metab. 2006 Dec;4(6):465-74. doi: 10.1016/j.cmet.2006.11.005. Cell Metab. 2006. PMID: 17141630 Free article.

2

Comparison of insulin secretory function in two mouse models with different susceptibility to beta-cell failure.

Kooptiwut S, Zraika S, Thorburn AW, Dunlop ME, Darwiche R, Kay TW, Proietto J, Andrikopoulos S. Kooptiwut S, et al. Among authors: kay tw. Endocrinology. 2002 Jun;143(6):2085-92. doi: 10.1210/endo.143.6.8859. Endocrinology. 2002. PMID: 12021173

3

Socs1 deficiency enhances hepatic insulin signaling.

Jamieson E, Chong MM, Steinberg GR, Jovanovska V, Fam BC, Bullen DV, Chen Y, Kemp BE, Proietto J, Kay TW, Andrikopoulos S. Jamieson E, et al. Among authors: kay tw. J Biol Chem. 2005 Sep 9;280(36):31516-21. doi: 10.1074/jbc.M502163200. Epub 2005 Jun 27. J Biol Chem. 2005. PMID: 15983045 Free article.

4

Perturbations in nuclear factor-kappaB or c-Jun N-terminal kinase pathways in pancreatic beta cells confer susceptibility to cytokine-induced cell death.

Thomas HE, Angstetra E, Fernandes RV, Mariana L, Irawaty W, Jamieson EL, Dudek NL, Kay TW. Thomas HE, et al. Among authors: kay tw. Immunol Cell Biol. 2006 Feb;84(1):20-7. doi: 10.1111/j.1440-1711.2005.01397.x. Epub 2005 Nov 7. Immunol Cell Biol. 2006. PMID: 16277639

5

Liver-specific suppressor of cytokine signaling-3 deletion in mice enhances hepatic insulin sensitivity and lipogenesis resulting in fatty liver and obesity.

Sachithanandan N, Fam BC, Fynch S, Dzamko N, Watt MJ, Wormald S, Honeyman J, Galic S, Proietto J, Andrikopoulos S, Hevener AL, Kay TW, Steinberg GR. Sachithanandan N, et al. Among authors: kay tw. Hepatology. 2010 Nov;52(5):1632-42. doi: 10.1002/hep.23861. Hepatology. 2010. PMID: 20799351

6

Macrophage deletion of SOCS1 increases sensitivity to LPS and palmitic acid and results in systemic inflammation and hepatic insulin resistance.

Sachithanandan N, Graham KL, Galic S, Honeyman JE, Fynch SL, Hewitt KA, Steinberg GR, Kay TW. Sachithanandan N, et al. Among authors: kay tw. Diabetes. 2011 Aug;60(8):2023-31. doi: 10.2337/db11-0259. Epub 2011 Jun 6. Diabetes. 2011. PMID: 21646388 Free PMC article.

7

Deficiency in interferon-gamma results in reduced body weight and better glucose tolerance in mice.

Wong N, Fam BC, Cempako GR, Steinberg GR, Walder K, Kay TW, Proietto J, Andrikopoulos S. Wong N, et al. Among authors: kay tw. Endocrinology. 2011 Oct;152(10):3690-9. doi: 10.1210/en.2011-0288. Epub 2011 Jul 26. Endocrinology. 2011. PMID: 21791564

8

Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity.

Galic S, Sachithanandan N, Kay TW, Steinberg GR. Galic S, et al. Among authors: kay tw. Biochem J. 2014 Jul 15;461(2):177-88. doi: 10.1042/BJ20140143. Biochem J. 2014. PMID: 24966052 Review.

9

Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release.

Scott JW, Galic S, Graham KL, Foitzik R, Ling NX, Dite TA, Issa SM, Langendorf CG, Weng QP, Thomas HE, Kay TW, Birnberg NC, Steinberg GR, Kemp BE, Oakhill JS. Scott JW, et al. Among authors: kay tw. Chem Biol. 2015 Jun 18;22(6):705-11. doi: 10.1016/j.chembiol.2015.05.011. Chem Biol. 2015. PMID: 26091167

10

Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice.

Wali JA, Galic S, Tan CY, Gurzov EN, Frazier AE, Connor T, Ge J, Pappas EG, Stroud D, Varanasi LC, Selck C, Ryan MT, Thorburn DR, Kemp BE, Krishnamurthy B, Kay TW, McGee SL, Thomas HE. Wali JA, et al. Among authors: kay tw. Cell Death Differ. 2018 Jan;25(1):217-225. doi: 10.1038/cdd.2017.168. Epub 2017 Oct 20. Cell Death Differ. 2018. PMID: 29053141 Free PMC article.

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