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Year Number of Results
1993 2
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1995 3
1996 6
1997 5
1998 8
1999 15
2000 20
2001 11
2002 14
2003 12
2004 9
2005 7
2006 1
2008 3
2009 3
2010 2
2011 2
2012 3
2013 2
2014 6
2015 5
2016 4
2017 4
2018 5
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2023 7
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172 results

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Page 1
Myasthenia gravis.
Gilhus NE, Tzartos S, Evoli A, Palace J, Burns TM, Verschuuren JJGM. Gilhus NE, et al. Nat Rev Dis Primers. 2019 May 2;5(1):30. doi: 10.1038/s41572-019-0079-y. Nat Rev Dis Primers. 2019. PMID: 31048702 Review.
Nucleoporin 50 mediates Kcna4 transcription to regulate cardiac electrical activity.
Gao X, Yu S, Guan Y, Shen Y, Xu L. Gao X, et al. J Cell Sci. 2021 Sep 15;134(18):jcs256818. doi: 10.1242/jcs.256818. Epub 2021 Sep 17. J Cell Sci. 2021. PMID: 34409458
Here, we show that Nup50, which is localized in the nucleus of cardiomyocytes, selectively induces an increase in the transcription and translation of Kcna4. The Kcna4 gene encodes a K+ voltage-gated channel of shaker-related subfamily member 4 and is essential for …
Here, we show that Nup50, which is localized in the nucleus of cardiomyocytes, selectively induces an increase in the transcription and tran …
KCNA4 Gene Variant is Auxiliary in Endurance Running Performance Level.
Flecha-Velazquez K, Fahey TD, Martínez JL, Lopez-Taylor JR, Rivera MA. Flecha-Velazquez K, et al. Int J Sports Med. 2019 May;40(5):354-358. doi: 10.1055/a-0824-5394. Epub 2019 Feb 27. Int J Sports Med. 2019. PMID: 30812034
Genomic DNA was purified from a whole blood sample. Polymerase chain reaction was used to amplify a KCNA4 SNP which consists of a C/T (rs1323860) transition. The observed genotype frequencies, in both Cases and Controls, met Hardy-Weinberg equilibrium (X(2), P0.05). ...The …
Genomic DNA was purified from a whole blood sample. Polymerase chain reaction was used to amplify a KCNA4 SNP which consists of a C/T …
KCNA4 deficiency leads to a syndrome of abnormal striatum, congenital cataract and intellectual disability.
Kaya N, Alsagob M, D'Adamo MC, Al-Bakheet A, Hasan S, Muccioli M, Almutairi FB, Almass R, Aldosary M, Monies D, Mustafa OM, Alyounes B, Kenana R, Al-Zahrani J, Naim E, Binhumaid FS, Qari A, Almutairi F, Meyer B, Plageman TF, Pessia M, Colak D, Al-Owain M. Kaya N, et al. J Med Genet. 2016 Nov;53(11):786-792. doi: 10.1136/jmedgenet-2015-103637. Epub 2016 Aug 31. J Med Genet. 2016. PMID: 27582084
OBJECTIVES: To describe a novel autosomal recessive syndrome associated with KCNA4 deficiency leading to congenital cataract, abnormal striatum, intellectual disability and attention deficit hyperactivity disorder. ...Co-expression of the wild type and mutant mRNAs resulte …
OBJECTIVES: To describe a novel autosomal recessive syndrome associated with KCNA4 deficiency leading to congenital cataract, abnorma …
miR-448 regulates potassium voltage-gated channel subfamily A member 4 (KCNA4) in ischemia and heart failure.
Kang GJ, Xie A, Kim E, Dudley SC Jr. Kang GJ, et al. Heart Rhythm. 2023 May;20(5):730-736. doi: 10.1016/j.hrthm.2023.01.021. Epub 2023 Jan 21. Heart Rhythm. 2023. PMID: 36693615 Free PMC article.
KCNA4 has a miR-448 binding site. OBJECTIVE: We investigated whether miR-448 was involved in the regulation of KCNA4 messenger RNA expression in ischemia. METHODS: Quantitative real-time reverse-transcriptase polymerase chain reaction was used to investigate the exp …
KCNA4 has a miR-448 binding site. OBJECTIVE: We investigated whether miR-448 was involved in the regulation of KCNA4 messenger …
The real thing.
Rosen MR. Rosen MR. Circ Res. 2000 Jul 7;87(1):6-7. doi: 10.1161/01.res.87.1.6. Circ Res. 2000. PMID: 10884364 No abstract available.
Genomic organization, nucleotide sequence, biophysical properties, and localization of the voltage-gated K+ channel gene KCNA4/Kv1.4 to mouse chromosome 2/human 11p14 and mapping of KCNC1/Kv3.1 to mouse 7/human 11p14.3-p15.2 and KCNA1/Kv1.1 to human 12p13.
Wymore RS, Korenberg JR, Kinoshita KD, Aiyar J, Coyne C, Chen XN, Hustad CM, Copeland NG, Gutman GA, Jenkins NA, et al. Wymore RS, et al. Genomics. 1994 Mar 15;20(2):191-202. doi: 10.1006/geno.1994.1153. Genomics. 1994. PMID: 8020965
A genomic clone encoding the Shaker-related potassium channel gene, Kcna4/mKv1.4, was isolated from mice. Its coding region is contained in a single exon, encodes a protein of 654 amino acids, and shares approximately 91% nucleotide sequence identity with human KCNA4 …
A genomic clone encoding the Shaker-related potassium channel gene, Kcna4/mKv1.4, was isolated from mice. Its coding region is contai …
Reduced excitability of gp130-deficient nociceptors is associated with increased voltage-gated potassium currents and Kcna4 channel upregulation.
Langeslag M, Malsch P, Welling A, Kress M. Langeslag M, et al. Pflugers Arch. 2014 Nov;466(11):2153-65. doi: 10.1007/s00424-014-1443-0. Epub 2014 Jan 25. Pflugers Arch. 2014. PMID: 24463703
Taqman RT-PCR analysis revealed significantly higher levels of Kcna4 mRNA, encoding A-type Kv1.4 potassium channel, in neuron cultures from SNS-gp130(-/-) versus control mice, which may account for the electrophysiological data. ...The present data show for the first time …
Taqman RT-PCR analysis revealed significantly higher levels of Kcna4 mRNA, encoding A-type Kv1.4 potassium channel, in neuron culture …
Molecular identity of Ito: Kv1.4 redux.
McKinnon D. McKinnon D. Circ Res. 1999 Mar 19;84(5):620-2. doi: 10.1161/01.res.84.5.620. Circ Res. 1999. PMID: 10082483 No abstract available.
Peripheral Ion Channel Genes Screening in Painful Small Fiber Neuropathy.
Ślęczkowska M, Almomani R, Marchi M, Salvi E, de Greef BTA, Sopacua M, Hoeijmakers JGJ, Lindsey P, Waxman SG, Lauria G, Faber CG, Smeets HJM, Gerrits MM. Ślęczkowska M, et al. Int J Mol Sci. 2022 Nov 15;23(22):14095. doi: 10.3390/ijms232214095. Int J Mol Sci. 2022. PMID: 36430572 Free PMC article.
Patients with SFN (n = 414) were analyzed for ANO1, ANO3, HCN1, KCNA2, KCNA4, KCNK18, KCNN1, KCNQ3, KCNQ5, KCNS1, TRPA1, TRPM8, TRPV1, TRPV3 and TRPV4 variants by single-molecule molecular inversion probes-next-generation sequencing. ...
Patients with SFN (n = 414) were analyzed for ANO1, ANO3, HCN1, KCNA2, KCNA4, KCNK18, KCNN1, KCNQ3, KCNQ5, KCNS1, TRPA1, TRPM8, TRPV1 …
172 results