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A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis.
Beckett EL, Stevens RL, Jarnicki AG, Kim RY, Hanish I, Hansbro NG, Deane A, Keely S, Horvat JC, Yang M, Oliver BG, van Rooijen N, Inman MD, Adachi R, Soberman RJ, Hamadi S, Wark PA, Foster PS, Hansbro PM. Beckett EL, et al. Among authors: keely s. J Allergy Clin Immunol. 2013 Mar;131(3):752-62. doi: 10.1016/j.jaci.2012.11.053. Epub 2013 Feb 4. J Allergy Clin Immunol. 2013. PMID: 23380220 Free PMC article.
Regulation of IL-12p40 by HIF controls Th1/Th17 responses to prevent mucosal inflammation.
Marks E, Naudin C, Nolan G, Goggins BJ, Burns G, Mateer SW, Latimore JK, Minahan K, Plank M, Foster PS, Callister R, Veysey M, Walker MM, Talley NJ, Radford-Smith G, Keely S. Marks E, et al. Among authors: keely s. Mucosal Immunol. 2017 Sep;10(5):1224-1236. doi: 10.1038/mi.2016.135. Epub 2017 Jan 25. Mucosal Immunol. 2017. PMID: 28120851 Free article.
Defects in NLRP6, autophagy and goblet cell homeostasis are associated with reduced duodenal CRH receptor 2 expression in patients with functional dyspepsia.
Bruce JK, Burns GL, Sinn Soh W, Nair PM, Sherwin S, Fan K, Dowling LR, Goggins BJ, Koloski N, Potter M, Bollipo S, Foster R, Gan LT, Veysey M, Philpott DJ, Girardin SE, Holtmann G, Kaiko GE, Walker MM, Talley NJ, Keely S. Bruce JK, et al. Among authors: keely s. Brain Behav Immun. 2022 Mar;101:335-345. doi: 10.1016/j.bbi.2022.01.019. Epub 2022 Jan 31. Brain Behav Immun. 2022. PMID: 35093492
Type 2 and type 17 effector cells are increased in the duodenal mucosa but not peripheral blood of patients with functional dyspepsia.
Burns GL, Bruce JK, Minahan K, Mathe A, Fairlie T, Cameron R, Naudin C, Nair PM, Potter MDE, Irani MZ, Bollipo S, Foster R, Gan LT, Shah A, Koloski NA, Foster PS, Horvat JC, Veysey M, Holtmann G, Powell N, Walker MM, Talley NJ, Keely S. Burns GL, et al. Among authors: keely s. Front Immunol. 2023 Jan 6;13:1051632. doi: 10.3389/fimmu.2022.1051632. eCollection 2022. Front Immunol. 2023. PMID: 36685573 Free PMC article.
263 results