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Method for generation of homogeneous multicellular tumor spheroids applicable to a wide variety of cell types.
Kelm JM, Timmins NE, Brown CJ, Fussenegger M, Nielsen LK. Kelm JM, et al. Biotechnol Bioeng. 2003 Jul 20;83(2):173-80. doi: 10.1002/bit.10655. Biotechnol Bioeng. 2003. PMID: 12768623
Heterologous protein production capacity of mammalian cells cultivated as monolayers and microtissues.
Sanchez-Bustamante CD, Kelm JM, Mitta B, Fussenegger M. Sanchez-Bustamante CD, et al. Among authors: kelm jm. Biotechnol Bioeng. 2006 Jan 5;93(1):169-80. doi: 10.1002/bit.20679. Biotechnol Bioeng. 2006. PMID: 16255048
Self-assembly of sensory neurons into ganglia-like microtissues.
Kelm JM, Ittner LM, Born W, Djonov V, Fussenegger M. Kelm JM, et al. J Biotechnol. 2006 Jan 2;121(1):86-101. doi: 10.1016/j.jbiotec.2005.07.009. Epub 2005 Sep 6. J Biotechnol. 2006. PMID: 16144726
An in vitro osteosarcoma 3D microtissue model for drug development.
Rimann M, Laternser S, Gvozdenovic A, Muff R, Fuchs B, Kelm JM, Graf-Hausner U. Rimann M, et al. Among authors: kelm jm. J Biotechnol. 2014 Nov 10;189:129-35. doi: 10.1016/j.jbiotec.2014.09.005. Epub 2014 Sep 16. J Biotechnol. 2014. PMID: 25234575
Towards automated production and drug sensitivity testing using scaffold-free spherical tumor microtissues.
Drewitz M, Helbling M, Fried N, Bieri M, Moritz W, Lichtenberg J, Kelm JM. Drewitz M, et al. Among authors: kelm jm. Biotechnol J. 2011 Dec;6(12):1488-96. doi: 10.1002/biot.201100290. Epub 2011 Nov 21. Biotechnol J. 2011. PMID: 22102438
InXy and SeXy, compact heterologous reporter proteins for mammalian cells.
Fluri DA, Kelm JM, Lesage G, Baba MD, Fussenegger M. Fluri DA, et al. Among authors: kelm jm. Biotechnol Bioeng. 2007 Oct 15;98(3):655-67. doi: 10.1002/bit.21461. Biotechnol Bioeng. 2007. PMID: 17461419
VEGF profiling and angiogenesis in human microtissues.
Kelm JM, Diaz Sanchez-Bustamante C, Ehler E, Hoerstrup SP, Djonov V, Ittner L, Fussenegger M. Kelm JM, et al. J Biotechnol. 2005 Aug 4;118(2):213-29. doi: 10.1016/j.jbiotec.2005.03.016. J Biotechnol. 2005. PMID: 15951040
3D spherical microtissues and microfluidic technology for multi-tissue experiments and analysis.
Kim JY, Fluri DA, Marchan R, Boonen K, Mohanty S, Singh P, Hammad S, Landuyt B, Hengstler JG, Kelm JM, Hierlemann A, Frey O. Kim JY, et al. Among authors: kelm jm. J Biotechnol. 2015 Jul 10;205:24-35. doi: 10.1016/j.jbiotec.2015.01.003. Epub 2015 Jan 12. J Biotechnol. 2015. PMID: 25592049
In vitro vascularization of human connective microtissues.
Kelm JM, Moritz W, Schmidt D, Hoerstrup SP, Fussenegger M. Kelm JM, et al. Methods Mol Med. 2007;140:153-66. doi: 10.1007/978-1-59745-443-8_9. Methods Mol Med. 2007. PMID: 18085208
A novel concept for scaffold-free vessel tissue engineering: self-assembly of microtissue building blocks.
Kelm JM, Lorber V, Snedeker JG, Schmidt D, Broggini-Tenzer A, Weisstanner M, Odermatt B, Mol A, Z√ľnd G, Hoerstrup SP. Kelm JM, et al. J Biotechnol. 2010 Jul 1;148(1):46-55. doi: 10.1016/j.jbiotec.2010.03.002. Epub 2010 Mar 17. J Biotechnol. 2010. PMID: 20223267
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