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1998 3
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Showing results for kevin single
Your search for Kevin Bingle retrieved no results
Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy.
Couturier CP, Ayyadhury S, Le PU, Nadaf J, Monlong J, Riva G, Allache R, Baig S, Yan X, Bourgey M, Lee C, Wang YCD, Wee Yong V, Guiot MC, Najafabadi H, Misic B, Antel J, Bourque G, Ragoussis J, Petrecca K. Couturier CP, et al. Nat Commun. 2020 Jul 8;11(1):3406. doi: 10.1038/s41467-020-17186-5. Nat Commun. 2020. PMID: 32641768 Free PMC article.
Our understanding of these processes, and how they relate to glioblastoma heterogeneity, is limited. To overcome these limitations, we performed single-cell RNA sequencing on 53586 adult glioblastoma cells and 22637 normal human fetal brain cells, and compared the lineage …
Our understanding of these processes, and how they relate to glioblastoma heterogeneity, is limited. To overcome these limitations, we perfo …
Anaphylaxis.
McLendon K, Sternard BT. McLendon K, et al. 2023 Jan 26. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Jan 26. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 29489197 Free Books & Documents.
Historically, anaphylactic reactions were categorized as IgE-mediated responses, while anaphylactoid reactions were categorized as IgE-independent events. Recently, these terms have been consolidated into a single diagnosis of anaphylaxis. Regardless of causation, the resu …
Historically, anaphylactic reactions were categorized as IgE-mediated responses, while anaphylactoid reactions were categorized as IgE-indep …
Paramyxovirus.
Park GYS, Tishkowski K. Park GYS, et al. 2023 Jul 10. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Jul 10. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 33620863 Free Books & Documents.
Paramyxoviruses are enveloped, single-stranded negative-sense RNA viruses that replicate in the cytoplasm. ...
Paramyxoviruses are enveloped, single-stranded negative-sense RNA viruses that replicate in the cytoplasm. ...
Global morbidity and mortality of central nervous system tuberculosis: a systematic review and meta-analysis.
Navarro-Flores A, Fernandez-Chinguel JE, Pacheco-Barrios N, Soriano-Moreno DR, Pacheco-Barrios K. Navarro-Flores A, et al. J Neurol. 2022 Jul;269(7):3482-3494. doi: 10.1007/s00415-022-11052-8. Epub 2022 Mar 15. J Neurol. 2022. PMID: 35288778 Free PMC article. Review.
BACKGROUND: Tuberculosis (TB) is the second most common cause of death due to a single infectious agent worldwide after COVID-19. Up to 15% of the cases are extrapulmonary, and if it is located in the central nervous system (CNS-TB), it presents high morbidity and mortalit …
BACKGROUND: Tuberculosis (TB) is the second most common cause of death due to a single infectious agent worldwide after COVID-19. Up …
Techniques for Single-Molecule mRNA Imaging in Living Cells.
Czaplinski K. Czaplinski K. Adv Exp Med Biol. 2017;978:425-441. doi: 10.1007/978-3-319-53889-1_22. Adv Exp Med Biol. 2017. PMID: 28523559 Review.
These techniques are also limited in their ability to examine intracellular spatial orientation of molecular activity, which is often a critical component to the regulation of biological processes, particularly in cells with unique spatial relationships, such as neurons. This mak …
These techniques are also limited in their ability to examine intracellular spatial orientation of molecular activity, which is often a crit …
Mutational spectrum of DMD mutations in dystrophinopathy patients: application of modern diagnostic techniques to a large cohort.
Flanigan KM, Dunn DM, von Niederhausern A, Soltanzadeh P, Gappmaier E, Howard MT, Sampson JB, Mendell JR, Wall C, King WM, Pestronk A, Florence JM, Connolly AM, Mathews KD, Stephan CM, Laubenthal KS, Wong BL, Morehart PJ, Meyer A, Finkel RS, Bonnemann CG, Medne L, Day JW, Dalton JC, Margolis MK, Hinton VJ; United Dystrophinopathy Project Consortium; Weiss RB. Flanigan KM, et al. Hum Mutat. 2009 Dec;30(12):1657-66. doi: 10.1002/humu.21114. Hum Mutat. 2009. PMID: 19937601 Free PMC article.
We note that 60% of these patients would be predicted to benefit from skipping of a single DMD exon using antisense oligonucleotide therapy, and 62% would be predicted to benefit from an inclusive multiexonskipping approach directed toward exons 45 through 55....
We note that 60% of these patients would be predicted to benefit from skipping of a single DMD exon using antisense oligonucleotide t …
Real-time 3D single molecule tracking.
Hou S, Exell J, Welsher K. Hou S, et al. Nat Commun. 2020 Jul 17;11(1):3607. doi: 10.1038/s41467-020-17444-6. Nat Commun. 2020. PMID: 32680983 Free PMC article.
Active feedback tracking is further applied to single proteins and nucleic acids, directly measuring the diffusion of various lengths (99 to 1385 bp) of single DNA molecules at rates up to 10 m(2)/s. In addition, 3D-SMART is able to quantify the occupancy of sing …
Active feedback tracking is further applied to single proteins and nucleic acids, directly measuring the diffusion of various lengths …
Biochemistry, Dihydrotestosterone.
Kinter KJ, Amraei R, Anekar AA. Kinter KJ, et al. 2023 Jul 30. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Jul 30. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 32491566 Free Books & Documents.
Applying the knowledge on dihydrotestosterone-related processes spans from the prenatal development of organs to aging-related complications in males. A clinician can single-handedly tackle the issues throughout the age spectrum. This hormone finds its utility as an essent …
Applying the knowledge on dihydrotestosterone-related processes spans from the prenatal development of organs to aging-related complications …
Targeting mutant KRAS.
Erlanson DA, Webster KR. Erlanson DA, et al. Curr Opin Chem Biol. 2021 Jun;62:101-108. doi: 10.1016/j.cbpa.2021.02.010. Epub 2021 Apr 7. Curr Opin Chem Biol. 2021. PMID: 33838397 Review.
Since 2018, five compounds have entered the clinic targeting a single mutant form of KRAS, G12C. Here, we review each of these compounds along with additional approaches to targeting this and other mutants. ...
Since 2018, five compounds have entered the clinic targeting a single mutant form of KRAS, G12C. Here, we review each of these compou …
Wound Irrigation.
Lewis K, Pay JL. Lewis K, et al. 2023 Mar 27. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Mar 27. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 30860757 Free Books & Documents.
Wound irrigation is an essential part of wound management and is the single greatest intervention in wound care that can reduce the risk of infection. ...
Wound irrigation is an essential part of wound management and is the single greatest intervention in wound care that can reduce the r …
784 results