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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 2
1998 1
2000 2
2001 2
2003 3
2004 3
2005 2
2006 3
2007 3
2008 2
2009 8
2010 4
2011 2
2012 3
2013 7
2014 8
2015 7
2016 13
2017 16
2018 15
2019 20
2020 23
2021 17
2022 17
2023 28
2024 9

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203 results

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Page 1
Computational benchmarking of putative KIFC1 inhibitors.
Sharma N, Setiawan D, Hamelberg D, Narayan R, Aneja R. Sharma N, et al. Med Res Rev. 2023 Mar;43(2):293-318. doi: 10.1002/med.21926. Epub 2022 Sep 14. Med Res Rev. 2023. PMID: 36104980 Review.
Many molecules have been identified as KIFC1 inhibitors because of their centrosome declustering activity in cancer cells. ...The current review aims to collate and present an in-depth analysis of known KIFC1 inhibitors and their biological activities. Additionally, …
Many molecules have been identified as KIFC1 inhibitors because of their centrosome declustering activity in cancer cells. ...The cur …
KIFC1: a promising chemotherapy target for cancer treatment?
Xiao YX, Yang WX. Xiao YX, et al. Oncotarget. 2016 Jul 26;7(30):48656-48670. doi: 10.18632/oncotarget.8799. Oncotarget. 2016. PMID: 27102297 Free PMC article. Review.
In this review we summarize a recent collection of information so as to provide a generalized picture of ideas and mechanisms against and in favor of KIFC1 as a chemotherapy target. And we also drew the conclusion that KIFC1 is a promising chemotherapy target for so …
In this review we summarize a recent collection of information so as to provide a generalized picture of ideas and mechanisms against and in …
Kinesin motor KIFC1 is required for tubulin acetylation and actin-dependent spindle migration in mouse oocyte meiosis.
Shan MM, Zou YJ, Pan ZN, Zhang HL, Xu Y, Ju JQ, Sun SC. Shan MM, et al. Development. 2022 Mar 1;149(5):dev200231. doi: 10.1242/dev.200231. Epub 2022 Mar 11. Development. 2022. PMID: 35142352
Mass spectroscopy analysis revealed that KIFC1 also associated with several actin nucleation factors and we found that KIFC1 was essential for the distribution of actin filaments, which further affected spindle migration. ...Exogenous KIFC1 mRNA supplement co …
Mass spectroscopy analysis revealed that KIFC1 also associated with several actin nucleation factors and we found that KIFC1 w …
KIFC1 Regulates the Trajectory of Neuronal Migration.
Muralidharan H, Guha S, Madugula K, Patil A, Bennison SA, Sun X, Toyo-Oka K, Baas PW. Muralidharan H, et al. J Neurosci. 2022 Mar 16;42(11):2149-2165. doi: 10.1523/JNEUROSCI.1708-21.2022. Epub 2022 Jan 19. J Neurosci. 2022. PMID: 35046122 Free PMC article.
For these studies, we used rat migratory neurons in vitro and developing mouse brain in vivo, together with RNA interference and ectopic expression of mutant forms of KIFC1. We found that crosslinking of microtubules into a nonsliding mode by KIFC1 is necessary for …
For these studies, we used rat migratory neurons in vitro and developing mouse brain in vivo, together with RNA interference and ectopic exp …
KIFC1 promotes proliferation and pseudo-bipolar division of ESCC through the transportation of Aurora B kinase.
Du B, Wei L, Wang J, Li Y, Huo J, Wang J, Wang P. Du B, et al. Aging (Albany NY). 2023 Nov 8;15(21):12633-12650. doi: 10.18632/aging.205203. Epub 2023 Nov 8. Aging (Albany NY). 2023. PMID: 37955677 Free PMC article.
To investigate the expression and function of KIFC1 in ESCC, we conducted immunohistochemical staining on 30 pairs of para-carcinoma tissue and cancerous tissues, revealing a significant increase in KIFC1 expression in ESCC tissues. Using siRNA to knock down KIFC …
To investigate the expression and function of KIFC1 in ESCC, we conducted immunohistochemical staining on 30 pairs of para-carcinoma …
KIFC1 promotes aerobic glycolysis in endometrial cancer cells by regulating the c-myc pathway.
Zhou K, Lin J, Dai M, He Y, Xu J, Lin Q. Zhou K, et al. J Bioenerg Biomembr. 2021 Dec;53(6):703-713. doi: 10.1007/s10863-021-09924-1. Epub 2021 Nov 3. J Bioenerg Biomembr. 2021. PMID: 34729671
Finally, KIFC1 knockdown inhibits tumor growth in vivo. The upregulation of KIFC1 was correlated with poor prognosis in EC. ...KIFC1 may be a potential target for the diagnosis and therapy of EC....
Finally, KIFC1 knockdown inhibits tumor growth in vivo. The upregulation of KIFC1 was correlated with poor prognosis in EC. .. …
ELK1/KIFC1 axis promotes breast cancer cell proliferation by regulating glutathione metabolism.
Yang B, Wang H, Xiao J, Chen W, Chen W. Yang B, et al. J Obstet Gynaecol Res. 2023 Aug;49(8):2175-2184. doi: 10.1111/jog.15710. Epub 2023 Jun 20. J Obstet Gynaecol Res. 2023. PMID: 37339943
RESULTS: This study demonstrated the upregulation of ELK1 and KIFC1 in BC and found that ELK1 could bind to the KIFC1 promoter to promote KIFC1 transcription. ...CONCLUSION: ELK1 was a transcriptional factor of KIFC1. ELK1/KIFC1 axis reduced ROS …
RESULTS: This study demonstrated the upregulation of ELK1 and KIFC1 in BC and found that ELK1 could bind to the KIFC1 promoter …
KIFC1 Is Associated with Basal Type, Cisplatin Resistance, PD-L1 Expression and Poor Prognosis in Bladder Cancer.
Sekino Y, Pham QT, Kobatake K, Kitano H, Ikeda K, Goto K, Hayashi T, Nakahara H, Sentani K, Oue N, Yasui W, Teishima J, Hinata N. Sekino Y, et al. J Clin Med. 2021 Oct 21;10(21):4837. doi: 10.3390/jcm10214837. J Clin Med. 2021. PMID: 34768355 Free PMC article.
This study aimed to analyze KIFC1 expression and examine KIFC1 involvement in cisplatin resistance in bladder cancer (BC). Immunohistochemistry showed that 37 of 78 (47.4%) BC cases were positive for KIFC1. KIFC1-positive cases were associated with hig …
This study aimed to analyze KIFC1 expression and examine KIFC1 involvement in cisplatin resistance in bladder cancer (BC). Imm …
KIFC1 regulates ZWINT to promote tumor progression and spheroid formation in colorectal cancer.
Akabane S, Oue N, Sekino Y, Asai R, Thang PQ, Taniyama D, Sentani K, Yukawa M, Toda T, Kimura KI, Egi H, Shimizu W, Ohdan H, Yasui W. Akabane S, et al. Pathol Int. 2021 Jul;71(7):441-452. doi: 10.1111/pin.13098. Epub 2021 Apr 5. Pathol Int. 2021. PMID: 33819373
This study aimed to analyze the expression and biological function of KIFC1 in CRC. Immunohistochemically, 67 (52%) of 129 CRC cases were positive for KIFC1 and statistically associated with poorer overall survival. ...Both KIFC1 and ZWINT knockdown cells att …
This study aimed to analyze the expression and biological function of KIFC1 in CRC. Immunohistochemically, 67 (52%) of 129 CRC cases …
KIFC1 functions in nuclear reshaping and midpiece formation during the spermatogenesis of small yellow croaker Larimichthys polyactis.
Zheng X, Gao X, Wang J, Du C, Hou C, Xie Q, Lou B, Liu F, Zhu J. Zheng X, et al. Anim Reprod Sci. 2021 Mar;226:106702. doi: 10.1016/j.anireprosci.2021.106702. Epub 2021 Jan 23. Anim Reprod Sci. 2021. PMID: 33581918
The C-terminal kinesin motor protein (KIFC1) has essential functions in spermatogenesis. To evaluate molecular mechanisms of KIFC1 during teleost fish spermatogenesis, there was cloning and sequencing the kifc1 cDNA in the testis of Larimichthys polyactis. .. …
The C-terminal kinesin motor protein (KIFC1) has essential functions in spermatogenesis. To evaluate molecular mechanisms of KIFC1 …
203 results