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Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response.
Behrendt R, Schumann T, Gerbaulet A, Nguyen LA, Schubert N, Alexopoulou D, Berka U, Lienenklaus S, Peschke K, Gibbert K, Wittmann S, Lindemann D, Weiss S, Dahl A, Naumann R, Dittmer U, Kim B, Mueller W, Gramberg T, Roers A. Behrendt R, et al. Among authors: kim b. Cell Rep. 2013 Aug 29;4(4):689-96. doi: 10.1016/j.celrep.2013.07.037. Epub 2013 Aug 22. Cell Rep. 2013. PMID: 23972988 Free PMC article.
SAMHD1 prevents autoimmunity by maintaining genome stability.
Kretschmer S, Wolf C, König N, Staroske W, Guck J, Häusler M, Luksch H, Nguyen LA, Kim B, Alexopoulou D, Dahl A, Rapp A, Cardoso MC, Shevchenko A, Lee-Kirsch MA. Kretschmer S, et al. Among authors: kim b. Ann Rheum Dis. 2015 Mar;74(3):e17. doi: 10.1136/annrheumdis-2013-204845. Epub 2014 Jan 20. Ann Rheum Dis. 2015. PMID: 24445253 Free PMC article.
Restriction of diverse retroviruses by SAMHD1.
Gramberg T, Kahle T, Bloch N, Wittmann S, Müllers E, Daddacha W, Hofmann H, Kim B, Lindemann D, Landau NR. Gramberg T, et al. Among authors: kim b. Retrovirology. 2013 Mar 5;10:26. doi: 10.1186/1742-4690-10-26. Retrovirology. 2013. PMID: 23497255 Free PMC article.
Host SAMHD1 protein promotes HIV-1 recombination in macrophages.
Nguyen LA, Kim DH, Daly MB, Allan KC, Kim B. Nguyen LA, et al. Among authors: kim b, kim dh. J Biol Chem. 2014 Jan 31;289(5):2489-96. doi: 10.1074/jbc.C113.522326. Epub 2013 Dec 18. J Biol Chem. 2014. PMID: 24352659 Free PMC article.
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