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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c.
Liu X, Kim CN, Yang J, Jemmerson R, Wang X. Liu X, et al. Among authors: kim cn. Cell. 1996 Jul 12;86(1):147-57. doi: 10.1016/s0092-8674(00)80085-9. Cell. 1996. PMID: 8689682
'Loop' domain deletional mutant of Bcl-xL is as effective as p29Bcl-xL in inhibiting radiation-induced cytosolic accumulation of cytochrome c (cyt c), caspase-3 activity, and apoptosis.
Burri SH, Kim CN, Fang G, Chang BS, Perkins C, Harris W, Davis LW, Thompson CB, Bhalla KN. Burri SH, et al. Among authors: kim cn. Int J Radiat Oncol Biol Phys. 1999 Jan 15;43(2):423-30. doi: 10.1016/s0360-3016(98)00385-x. Int J Radiat Oncol Biol Phys. 1999. PMID: 10030271
Temporal relationship of CDK1 activation and mitotic arrest to cytosolic accumulation of cytochrome C and caspase-3 activity during Taxol-induced apoptosis of human AML HL-60 cells.
Ibrado AM, Kim CN, Bhalla K. Ibrado AM, et al. Among authors: kim cn. Leukemia. 1998 Dec;12(12):1930-6. doi: 10.1038/sj.leu.2401218. Leukemia. 1998. PMID: 9844922
Overexpression of Apaf-1 promotes apoptosis of untreated and paclitaxel- or etoposide-treated HL-60 cells.
Perkins C, Kim CN, Fang G, Bhalla KN. Perkins C, et al. Among authors: kim cn. Cancer Res. 1998 Oct 15;58(20):4561-6. Cancer Res. 1998. PMID: 9788601
"Loop" domain is necessary for taxol-induced mobility shift and phosphorylation of Bcl-2 as well as for inhibiting taxol-induced cytosolic accumulation of cytochrome c and apoptosis.
Fang G, Chang BS, Kim CN, Perkins C, Thompson CB, Bhalla KN. Fang G, et al. Among authors: kim cn. Cancer Res. 1998 Aug 1;58(15):3202-8. Cancer Res. 1998. PMID: 9699642
Overexpression of Bcl-X(L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis.
Kim CN, Wang X, Huang Y, Ibrado AM, Liu L, Fang G, Bhalla K. Kim CN, et al. Cancer Res. 1997 Aug 1;57(15):3115-20. Cancer Res. 1997. PMID: 9242435
Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked.
Yang J, Liu X, Bhalla K, Kim CN, Ibrado AM, Cai J, Peng TI, Jones DP, Wang X. Yang J, et al. Among authors: kim cn. Science. 1997 Feb 21;275(5303):1129-32. doi: 10.1126/science.275.5303.1129. Science. 1997. PMID: 9027314
Purification and characterization of an interleukin-1beta-converting enzyme family protease that activates cysteine protease P32 (CPP32).
Liu X, Kim CN, Pohl J, Wang X. Liu X, et al. Among authors: kim cn. J Biol Chem. 1996 Jun 7;271(23):13371-6. J Biol Chem. 1996. PMID: 8662833
Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor and Ara-C exert synergistic toxicity against human AML HL-60 cells.
Kim CN, Bhalla K, Kreitman RJ, Willingham MC, Hall P, Tagge EP, Jia T, Frankel AE. Kim CN, et al. Leuk Res. 1999 Jun;23(6):527-38. doi: 10.1016/s0145-2126(99)00039-9. Leuk Res. 1999. PMID: 10374846
Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling.
Balachandran S, Kim CN, Yeh WC, Mak TW, Bhalla K, Barber GN. Balachandran S, et al. Among authors: kim cn. EMBO J. 1998 Dec 1;17(23):6888-902. doi: 10.1093/emboj/17.23.6888. EMBO J. 1998. PMID: 9843495 Free PMC article.
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