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ApoE suppresses atherosclerosis by reducing lipid accumulation in circulating monocytes and the expression of inflammatory molecules on monocytes and vascular endothelium.
Gaudreault N, Kumar N, Posada JM, Stephens KB, Reyes de Mochel NS, Eberlé D, Olivas VR, Kim RY, Harms MJ, Johnson S, Messina LM, Rapp JH, Raffai RL. Gaudreault N, et al. Among authors: kim ry. Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):264-72. doi: 10.1161/ATVBAHA.111.238964. Epub 2011 Nov 3. Arterioscler Thromb Vasc Biol. 2012. PMID: 22053073 Free PMC article.
Inducible ApoE gene repair in hypomorphic ApoE mice deficient in the low-density lipoprotein receptor promotes atheroma stabilization with a human-like lipoprotein profile.
Eberlé D, Luk FS, Kim RY, Olivas VR, Kumar N, Posada JM, Li K, Gaudreault N, Rapp JH, Raffai RL. Eberlé D, et al. Among authors: kim ry. Arterioscler Thromb Vasc Biol. 2013 Aug;33(8):1759-67. doi: 10.1161/ATVBAHA.112.300605. Epub 2013 Jun 20. Arterioscler Thromb Vasc Biol. 2013. PMID: 23788760 Free PMC article.
Immunosuppression With FTY720 Reverses Cardiac Dysfunction in Hypomorphic ApoE Mice Deficient in SR-BI Expression That Survive Myocardial Infarction Caused by Coronary Atherosclerosis.
Luk FS, Kim RY, Li K, Ching D, Wong DK, Joshi SK, Imhof I, Honbo N, Hoover H, Zhu BQ, Lovett DH, Karliner JS, Raffai RL. Luk FS, et al. Among authors: kim ry. J Cardiovasc Pharmacol. 2016 Jan;67(1):47-56. doi: 10.1097/FJC.0000000000000312. J Cardiovasc Pharmacol. 2016. PMID: 26322923 Free PMC article.
454 results