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Vaccination of colorectal cancer patients with modified vaccinia ankara encoding the tumor antigen 5T4 (TroVax) given alongside chemotherapy induces potent immune responses.
Harrop R, Drury N, Shingler W, Chikoti P, Redchenko I, Carroll MW, Kingsman SM, Naylor S, Melcher A, Nicholls J, Wassan H, Habib N, Anthoney A. Harrop R, et al. Among authors: kingsman sm. Clin Cancer Res. 2007 Aug 1;13(15 Pt 1):4487-94. doi: 10.1158/1078-0432.CCR-07-0704. Clin Cancer Res. 2007. PMID: 17671134 Clinical Trial.
Phase I study of MetXia-P450 gene therapy and oral cyclophosphamide for patients with advanced breast cancer or melanoma.
Braybrooke JP, Slade A, Deplanque G, Harrop R, Madhusudan S, Forster MD, Gibson R, Makris A, Talbot DC, Steiner J, White L, Kan O, Naylor S, Carroll MW, Kingsman SM, Harris AL. Braybrooke JP, et al. Among authors: kingsman sm. Clin Cancer Res. 2005 Feb 15;11(4):1512-20. doi: 10.1158/1078-0432.CCR-04-0155. Clin Cancer Res. 2005. PMID: 15746054 Clinical Trial.
Vaccination of colorectal cancer patients with modified vaccinia Ankara delivering the tumor antigen 5T4 (TroVax) induces immune responses which correlate with disease control: a phase I/II trial.
Harrop R, Connolly N, Redchenko I, Valle J, Saunders M, Ryan MG, Myers KA, Drury N, Kingsman SM, Hawkins RE, Carroll MW. Harrop R, et al. Among authors: kingsman sm. Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3416-24. doi: 10.1158/1078-0432.CCR-05-2732. Clin Cancer Res. 2006. PMID: 16740766 Clinical Trial.
Vaccination of colorectal cancer patients with TroVax given alongside chemotherapy (5-fluorouracil, leukovorin and irinotecan) is safe and induces potent immune responses.
Harrop R, Drury N, Shingler W, Chikoti P, Redchenko I, Carroll MW, Kingsman SM, Naylor S, Griffiths R, Steven N, Hawkins RE. Harrop R, et al. Among authors: kingsman sm. Cancer Immunol Immunother. 2008 Jul;57(7):977-86. doi: 10.1007/s00262-007-0428-7. Cancer Immunol Immunother. 2008. PMID: 18060404 Free PMC article. Clinical Trial.
149 results