Kirschner K - Search Results

1

Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion.

Kent DG, Li J, Tanna H, Fink J, Kirschner K, Pask DC, Silber Y, Hamilton TL, Sneade R, Simons BD, Green AR. Kent DG, et al. Among authors: kirschner k. PLoS Biol. 2013;11(6):e1001576. doi: 10.1371/journal.pbio.1001576. Epub 2013 Jun 4. PLoS Biol. 2013. PMID: 23750118 Free PMC article.

2

Cytokine-induced megakaryocytic differentiation is regulated by genome-wide loss of a uSTAT transcriptional program.

Park HJ, Li J, Hannah R, Biddie S, Leal-Cervantes AI, Kirschner K, Flores Santa Cruz D, Sexl V, Göttgens B, Green AR. Park HJ, et al. Among authors: kirschner k. EMBO J. 2016 Mar 15;35(6):580-94. doi: 10.15252/embj.201592383. Epub 2015 Dec 23. EMBO J. 2016. PMID: 26702099 Free PMC article.

3

SC3: consensus clustering of single-cell RNA-seq data.

Kiselev VY, Kirschner K, Schaub MT, Andrews T, Yiu A, Chandra T, Natarajan KN, Reik W, Barahona M, Green AR, Hemberg M. Kiselev VY, et al. Among authors: kirschner k. Nat Methods. 2017 May;14(5):483-486. doi: 10.1038/nmeth.4236. Epub 2017 Mar 27. Nat Methods. 2017. PMID: 28346451 Free PMC article.

4

Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

Kirschner K, Chandra T, Kiselev V, Flores-Santa Cruz D, Macaulay IC, Park HJ, Li J, Kent DG, Kumar R, Pask DC, Hamilton TL, Hemberg M, Reik W, Green AR. Kirschner K, et al. Cell Rep. 2017 May 23;19(8):1503-1511. doi: 10.1016/j.celrep.2017.04.074. Cell Rep. 2017. PMID: 28538171 Free PMC article.

5

Multiplexing for Oxidative Bisulfite Sequencing (oxBS-seq).

Kirschner K, Krueger F, Green AR, Chandra T. Kirschner K, et al. Methods Mol Biol. 2018;1708:665-678. doi: 10.1007/978-1-4939-7481-8_34. Methods Mol Biol. 2018. PMID: 29224169 Free article.

6

p57Kip2 regulates embryonic blood stem cells by controlling sympathoadrenal progenitor expansion.

Kapeni C, Nitsche L, Kilpatrick AM, Wilson NK, Xia K, Mirshekar-Syahkal B, Chandrakanthan V, Malouf C, Pimanda JE, Göttgens B, Kirschner K, Tomlinson SR, Ottersbach K. Kapeni C, et al. Among authors: kirschner k. Blood. 2022 Aug 4;140(5):464-477. doi: 10.1182/blood.2021014853. Blood. 2022. PMID: 35653588 Free PMC article.

7

Notch Signaling Mediates Secondary Senescence.

Teo YV, Rattanavirotkul N, Olova N, Salzano A, Quintanilla A, Tarrats N, Kiourtis C, Müller M, Green AR, Adams PD, Acosta JC, Bird TG, Kirschner K, Neretti N, Chandra T. Teo YV, et al. Among authors: kirschner k. Cell Rep. 2019 Apr 23;27(4):997-1007.e5. doi: 10.1016/j.celrep.2019.03.104. Cell Rep. 2019. PMID: 31018144 Free PMC article.

8

Identification of curaxin as a potential new therapeutic for JAK2 V617F mutant patients.

Pearson S, Blance R, Yan F, Hsieh YC, Geary B, Amaral FMR, Somervaille TCP, Kirschner K, Whetton AD, Pierce A. Pearson S, et al. Among authors: kirschner k. PLoS One. 2023 May 30;18(5):e0286412. doi: 10.1371/journal.pone.0286412. eCollection 2023. PLoS One. 2023. PMID: 37253035 Free PMC article.

9

Unraveling Heterogeneity in the Aging Hematopoietic Stem Cell Compartment: An Insight From Single-cell Approaches.

Yang F, Nourse C, Helgason GV, Kirschner K. Yang F, et al. Among authors: kirschner k. Hemasphere. 2023 May 26;7(6):e895. doi: 10.1097/HS9.0000000000000895. eCollection 2023 Jun. Hemasphere. 2023. PMID: 37304939 Free PMC article. Review.

10

Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53.

Kirschner K, Samarajiwa SA, Cairns JM, Menon S, Pérez-Mancera PA, Tomimatsu K, Bermejo-Rodriguez C, Ito Y, Chandra T, Narita M, Lyons SK, Lynch AG, Kimura H, Ohbayashi T, Tavaré S, Narita M. Kirschner K, et al. PLoS Genet. 2015 Mar 19;11(3):e1005053. doi: 10.1371/journal.pgen.1005053. eCollection 2015 Mar. PLoS Genet. 2015. PMID: 25790137 Free PMC article.

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