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Prediction of in vitro metabolic stability of calcitriol analogs by QSAR.
Jensen BF, Sørensen MD, Kissmeyer AM, Björkling F, Sonne K, Engelsen SB, Nørgaard L. Jensen BF, et al. Among authors: kissmeyer am. J Comput Aided Mol Des. 2003 Dec;17(12):849-59. doi: 10.1023/b:jcam.0000021861.31978.da. J Comput Aided Mol Des. 2003. PMID: 15124933
Enhanced biological activity of 1alpha,25-dihydroxy-20-epi-vitamin D3, the C-20 epimer of 1alpha,25-dihydroxyvitamin D3, is in part due to its metabolism into stable intermediary metabolites with significant biological activity.
Siu-Caldera ML, Sekimoto H, Peleg S, Nguyen C, Kissmeyer AM, Binderup L, Weiskopf A, Vouros P, Uskoković MR, Reddy GS. Siu-Caldera ML, et al. Among authors: kissmeyer am. J Steroid Biochem Mol Biol. 1999 Dec 15;71(3-4):111-21. doi: 10.1016/s0960-0760(99)00130-2. J Steroid Biochem Mol Biol. 1999. PMID: 10659699
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