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Gefapixant in two randomised dose-escalation studies in chronic cough.
Smith JA, Kitt MM, Butera P, Smith SA, Li Y, Xu ZJ, Holt K, Sen S, Sher MR, Ford AP. Smith JA, et al. Among authors: kitt mm. Eur Respir J. 2020 Mar 20;55(3):1901615. doi: 10.1183/13993003.01615-2019. Print 2020 Mar. Eur Respir J. 2020. PMID: 31949115 Free article. Clinical Trial.
Author response: The human cough reflex has separate, distinct pathways.
Morice AH, Kitt MM, Ford AP, Tershakovec AM, Wu WC, Brindle K, Thompson R, Thackray-Nocera S, Wright C. Morice AH, et al. Among authors: kitt mm. Eur Respir J. 2020 Feb 6;55(2):1902312. doi: 10.1183/13993003.02312-2019. Print 2020 Feb. Eur Respir J. 2020. PMID: 32029646 Free article. No abstract available.
Gefapixant, a P2X3 receptor antagonist, for the treatment of refractory or unexplained chronic cough: a randomised, double-blind, controlled, parallel-group, phase 2b trial.
Smith JA, Kitt MM, Morice AH, Birring SS, McGarvey LP, Sher MR, Li YP, Wu WC, Xu ZJ, Muccino DR, Ford AP; Protocol 012 Investigators. Smith JA, et al. Among authors: kitt mm. Lancet Respir Med. 2020 Aug;8(8):775-785. doi: 10.1016/S2213-2600(19)30471-0. Epub 2020 Feb 25. Lancet Respir Med. 2020. PMID: 32109425 Clinical Trial.
The discovery and development of gefapixant.
Ford AP, Dillon MP, Kitt MM, Gever JR. Ford AP, et al. Among authors: kitt mm. Auton Neurosci. 2021 Nov;235:102859. doi: 10.1016/j.autneu.2021.102859. Epub 2021 Jul 31. Auton Neurosci. 2021. PMID: 34403981
Clinical trial: the efficacy and tolerability of velusetrag, a selective 5-HT4 agonist with high intrinsic activity, in chronic idiopathic constipation - a 4-week, randomized, double-blind, placebo-controlled, dose-response study.
Goldberg M, Li YP, Johanson JF, Mangel AW, Kitt M, Beattie DT, Kersey K, Daniels O. Goldberg M, et al. Aliment Pharmacol Ther. 2010 Nov;32(9):1102-12. doi: 10.1111/j.1365-2036.2010.04456.x. Epub 2010 Sep 22. Aliment Pharmacol Ther. 2010. PMID: 21039672 Free article. Clinical Trial.
Effects of integrelin, a platelet glycoprotein IIb/IIIa receptor antagonist, in unstable angina. A randomized multicenter trial.
Schulman SP, Goldschmidt-Clermont PJ, Topol EJ, Califf RM, Navetta FI, Willerson JT, Chandra NC, Guerci AD, Ferguson JJ, Harrington RA, Lincoff AM, Yakubov SJ, Bray PF, Bahr RD, Wolfe CL, Yock PG, Anderson HV, Nygaard TW, Mason SJ, Effron MB, Fatterpacker A, Raskin S, Smith J, Brashears L, Gottdiener P, du Mee C, Kitt MM, Gerstenblith G. Schulman SP, et al. Among authors: kitt mm. Circulation. 1996 Nov 1;94(9):2083-9. doi: 10.1161/01.cir.94.9.2083. Circulation. 1996. PMID: 8901655 Clinical Trial.
80 results