Klippel A - Search Results

1

A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium.

Santel A, Aleku M, Keil O, Endruschat J, Esche V, Fisch G, Dames S, Löffler K, Fechtner M, Arnold W, Giese K, Klippel A, Kaufmann J. Santel A, et al. Among authors: klippel a. Gene Ther. 2006 Aug;13(16):1222-34. doi: 10.1038/sj.gt.3302777. Epub 2006 Apr 20. Gene Ther. 2006. PMID: 16625243

2

RNA interference in the mouse vascular endothelium by systemic administration of siRNA-lipoplexes for cancer therapy.

Santel A, Aleku M, Keil O, Endruschat J, Esche V, Durieux B, Löffler K, Fechtner M, Röhl T, Fisch G, Dames S, Arnold W, Giese K, Klippel A, Kaufmann J. Santel A, et al. Among authors: klippel a. Gene Ther. 2006 Sep;13(18):1360-70. doi: 10.1038/sj.gt.3302778. Epub 2006 Apr 20. Gene Ther. 2006. PMID: 16625242

3

Functional studies of the PI(3)-kinase signalling pathway employing synthetic and expressed siRNA.

Czauderna F, Fechtner M, Aygün H, Arnold W, Klippel A, Giese K, Kaufmann J. Czauderna F, et al. Among authors: klippel a. Nucleic Acids Res. 2003 Jan 15;31(2):670-82. doi: 10.1093/nar/gkg141. Nucleic Acids Res. 2003. PMID: 12527776 Free PMC article.

4

Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells.

Czauderna F, Fechtner M, Dames S, Aygün H, Klippel A, Pronk GJ, Giese K, Kaufmann J. Czauderna F, et al. Among authors: klippel a. Nucleic Acids Res. 2003 Jun 1;31(11):2705-16. doi: 10.1093/nar/gkg393. Nucleic Acids Res. 2003. PMID: 12771196 Free PMC article.

5

Inducible shRNA expression for application in a prostate cancer mouse model.

Czauderna F, Santel A, Hinz M, Fechtner M, Durieux B, Fisch G, Leenders F, Arnold W, Giese K, Klippel A, Kaufmann J. Czauderna F, et al. Among authors: klippel a. Nucleic Acids Res. 2003 Nov 1;31(21):e127. doi: 10.1093/nar/gng127. Nucleic Acids Res. 2003. PMID: 14576327 Free PMC article.

6

Knockdown of MTP18, a novel phosphatidylinositol 3-kinase-dependent protein, affects mitochondrial morphology and induces apoptosis.

Tondera D, Santel A, Schwarzer R, Dames S, Giese K, Klippel A, Kaufmann J. Tondera D, et al. Among authors: klippel a. J Biol Chem. 2004 Jul 23;279(30):31544-55. doi: 10.1074/jbc.M404704200. Epub 2004 May 20. J Biol Chem. 2004. PMID: 15155745 Free article.

7

PKN3 is required for malignant prostate cell growth downstream of activated PI 3-kinase.

Leenders F, Möpert K, Schmiedeknecht A, Santel A, Czauderna F, Aleku M, Penschuck S, Dames S, Sternberger M, Röhl T, Wellmann A, Arnold W, Giese K, Kaufmann J, Klippel A. Leenders F, et al. Among authors: klippel a. EMBO J. 2004 Aug 18;23(16):3303-13. doi: 10.1038/sj.emboj.7600345. Epub 2004 Jul 29. EMBO J. 2004. PMID: 15282551 Free PMC article.

8

Identification of novel effectors of invasive cell growth downstream of phosphoinositide 3-kinase.

Kaufmann J, Pronk G, Giese K, Klippel A. Kaufmann J, et al. Among authors: klippel a. Biochem Soc Trans. 2004 Apr;32(Pt 2):355-9. doi: 10.1042/bst0320355. Biochem Soc Trans. 2004. PMID: 15046608 Review.

9

Unravelling novel intracellular pathways in cell-based assays.

Giese K, Kaufmann J, Pronk GJ, Klippel A. Giese K, et al. Among authors: klippel a. Drug Discov Today. 2002 Feb 1;7(3):179-86. doi: 10.1016/s1359-6446(01)02126-2. Drug Discov Today. 2002. PMID: 11815234 Review.

10

REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase.

Schwarzer R, Tondera D, Arnold W, Giese K, Klippel A, Kaufmann J. Schwarzer R, et al. Among authors: klippel a. Oncogene. 2005 Feb 10;24(7):1138-49. doi: 10.1038/sj.onc.1208236. Oncogene. 2005. PMID: 15592522

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